Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Aaron E Foster"'
Autor:
Xiaomeng Hu, Karl Manner, Rowena DeJesus, Kathy White, Corie Gattis, Priscilla Ngo, Christopher Bandoro, Eleonore Tham, Elaine Y. Chu, Chi Young, Frank Wells, Ronald Basco, Annabelle Friera, Divy Kangeyan, Pascal Beauchesne, William E. Dowdle, Tobias Deuse, Terry J. Fry, Aaron E. Foster, Sonja Schrepfer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Manufacturing autologous chimeric antigen receptor (CAR) T cell therapeutics is complex, and many patients experience treatment delays or cannot be treated at all. Although current allogeneic CAR products have the potential to overcome manuf
Externí odkaz:
https://doaj.org/article/11a7498d8b624c7f9293ade72a94e6d3
Autor:
MyLinh T. Duong, Matthew R. Collinson-Pautz, Eva Morschl, An Lu, Slawomir P. Szymanski, Ming Zhang, Mary E. Brandt, Wei-Chun Chang, Kelly L. Sharp, Steven M. Toler, Kevin M. Slawin, Aaron E. Foster, David M. Spencer, J. Henri Bayle
Publikováno v:
Molecular Therapy: Oncolytics, Vol 12, Iss , Pp 124-137 (2019)
Use of chimeric antigen receptors (CARs) as the basis of targeted adoptive T cell therapies has enabled dramatic efficacy against multiple hematopoietic malignancies, but potency against bulky and solid tumors has lagged, potentially due to insuffici
Externí odkaz:
https://doaj.org/article/2fbebd3dad654aee828c680d5ac36e2b
Autor:
J. Henri Bayle, Aaron E. Foster, David M. Spencer, Kelly L. Sharp, Xiaomei Wang, Fabricio G. Cabrera
Publikováno v:
Mol Ther
Allogeneic, off-the-shelf (OTS) chimeric antigen receptor (CAR) cell therapies have the potential to reduce manufacturing costs and variability while providing broader accessibility to cancer patients and those with other diseases. However, host-vers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28db584d332ff81077518a508b7e85d
https://doi.org/10.1016/j.ymthe.2020.10.019
https://doi.org/10.1016/j.ymthe.2020.10.019
Autor:
Aaron E. Foster, J. Henri Bayle, Xiaomei Wang, Jan L. Medina, Daniel L. Jasinski, David M. Spencer
Publikováno v:
Blood Adv
Natural killer (NK) cells expressing chimeric antigen receptors (CARs) are a promising anticancer immunotherapy, leveraging both innate NK cell antitumor activity and target-specific cytotoxicity. Inducible MyD88/CD40 (iMC) is a potent, rimiducid-reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bad121de5ce3516833aefe12d8f768
https://doi.org/10.1182/bloodadvances.2020001510
https://doi.org/10.1182/bloodadvances.2020001510
Publikováno v:
Cytotherapy. 21:1246-1257
Background Gas Permeable Rapid Expansion (G-Rex) bioreactors have been shown to efficiently expand immune cells intended for therapeutic use, but do not address the complexity of the viral transduction step required for many engineered T-cell product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06540472f519224612f76c24a39161f
https://doi.org/10.1016/j.jcyt.2019.10.006
https://doi.org/10.1016/j.jcyt.2019.10.006
Autor:
Daniel L Galvan, Richard T O'Neil, Aaron E Foster, Leslie Huye, Adham Bear, Cliona M Rooney, Matthew H Wilson
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140744 (2015)
Adoptive transfer of gene modified T cells provides possible immunotherapy for patients with cancers refractory to other treatments. We have previously used the non-viral piggyBac transposon system to gene modify human T cells for potential immunothe
Externí odkaz:
https://doaj.org/article/b8c8c62a7f8847d2ba18d2805d1633d3
Autor:
An Lu, Kelly L. Sharp, Wei-Chun Chang, Kevin M. Slawin, Slawomir P. Szymanski, Steven M. Toler, Ming Zhang, Eva Morschl, David M. Spencer, Matthew R. Collinson-Pautz, My Linh T. Duong, J. Henri Bayle, Mary E. Brandt, Aaron E. Foster
Publikováno v:
Molecular Therapy: Oncolytics, Vol 12, Iss, Pp 124-137 (2019)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Use of chimeric antigen receptors (CARs) as the basis of targeted adoptive T cell therapies has enabled dramatic efficacy against multiple hematopoietic malignancies, but potency against bulky and solid tumors has lagged, potentially due to insuffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea3ccbe3a4f7ff4b8f73320ec846449
http://www.sciencedirect.com/science/article/pii/S2372770518300469
http://www.sciencedirect.com/science/article/pii/S2372770518300469
Autor:
Aaron E. Foster, Mary E. Brandt, Kevin M. Slawin, David M. Spencer, Matthew R. Collinson-Pautz, Pei-Yi Lin, Mariam Khalil, Nicholas P. Shinners, My Linh T. Duong, J. Henri Bayle, Aruna Mahendravada, Wei-Chun Chang, Ming Zhang, An Lu, Jeannette Crisostomo
Publikováno v:
Leukemia
Successful adoptive chimeric antigen receptor (CAR) T-cell therapies against hematological malignancies require CAR-T expansion and durable persistence following infusion. Balancing increased CAR-T potency with safety, including severe cytokine-relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e30e133078c58b79fdbde0dbc893bc7
https://doi.org/10.1038/s41375-019-0417-9
https://doi.org/10.1038/s41375-019-0417-9
Autor:
Faith Brianne Buchanan, Winnie W. Y. Lau, Kaitlin Morrison, Natalie S Grover, Robert S. Hagan, Barbara Savoldo, Spencer Laing, James M. Coghill, John A. West, Matthew C. Foster, Gianpietro Dotti, Paul M. Armistead, Clio Rubinos, Catherine Cheng, Aaron E. Foster, Jonathan S. Serody, Anastasia Ivanova
Publikováno v:
Blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b2086bc61ec56eab71283b6ee443fc
https://pubmed.ncbi.nlm.nih.gov/33624095
https://pubmed.ncbi.nlm.nih.gov/33624095
Autor:
Adham S Bear, Laura C Kennedy, Joseph K Young, Serena K Perna, Joao Paulo Mattos Almeida, Adam Y Lin, Phillip C Eckels, Rebekah A Drezek, Aaron E Foster
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69073 (2013)
Ablative treatments such as photothermal therapy (PTT) are attractive anticancer strategies because they debulk accessible tumor sites while simultaneously priming antitumor immune responses. However, the immune response following thermal ablation is
Externí odkaz:
https://doaj.org/article/5669772c71314b089987371bba19e559