Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Aaron Diaz"'
Autor:
Saket Jain, Jonathan W. Rick, Rushikesh S. Joshi, Angad Beniwal, Jordan Spatz, Sabraj Gill, Alexander Chih-Chieh Chang, Nikita Choudhary, Alan T. Nguyen, Sweta Sudhir, Eric J. Chalif, Jia-Shu Chen, Ankush Chandra, Alexander F. Haddad, Harsh Wadhwa, Sumedh S. Shah, Serah Choi, Josie L. Hayes, Lin Wang, Garima Yagnik, Joseph F. Costello, Aaron Diaz, Dieter Henrik Heiland, Manish K. Aghi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 5 (2023)
Cancer-associated fibroblasts (CAFs) were presumed absent in glioblastoma given the lack of brain fibroblasts. Serial trypsinization of glioblastoma specimens yielded cells with CAF morphology and single-cell transcriptomic profiles based on their la
Externí odkaz:
https://doaj.org/article/14cced134af940a49b4d6fa72e0c4da9
Autor:
Laura Pinton, Elena Masetto, Marina Vettore, Samantha Solito, Sara Magri, Marta D’Andolfi, Paola Del Bianco, Giovanna Lollo, Jean-Pierre Benoit, Hideho Okada, Aaron Diaz, Alessandro Della Puppa, Susanna Mandruzzato
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background Systemic and local immune suppression plays a significant role in glioma progression. Glioma microenvironment contains both brain-resident microglial cells (MG) and bone marrow-derived macrophages (BMDM), but the study of their fu
Externí odkaz:
https://doaj.org/article/c92e2118ef024d7281d5ce47a312ac6b
Autor:
Sören Müller, Gary Kohanbash, S. John Liu, Beatriz Alvarado, Diego Carrera, Aparna Bhaduri, Payal B. Watchmaker, Garima Yagnik, Elizabeth Di Lullo, Martina Malatesta, Nduka M. Amankulor, Arnold R. Kriegstein, Daniel A. Lim, Manish Aghi, Hideho Okada, Aaron Diaz
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Tumor-associated macrophages (TAMs) are abundant in gliomas and immunosuppressive TAMs are a barrier to emerging immunotherapies. It is unknown to what extent macrophages derived from peripheral blood adopt the phenotype of brain-
Externí odkaz:
https://doaj.org/article/b3ec0e0d5c1c43f3ad2d248d295ddd67
Autor:
Sören Müller, Aaron Diaz
Publikováno v:
Frontiers in Genetics, Vol 8 (2017)
Critical cancer mutations are often regional and mosaic, confounding the efficacy of targeted therapeutics. Single cell mRNA sequencing (scRNA-seq) has enabled unprecedented studies of intra-tumor heterogeneity and its role in cancer progression, met
Externí odkaz:
https://doaj.org/article/b7fc3ffcd5e14cc0a3d1ded90bbc69a5
Autor:
Miyuki Suzawa, Diego A Miranda, Karmela A Ramos, Kenny K-H Ang, Emily J Faivre, Christopher G Wilson, Laura Caboni, Michelle R Arkin, Yeong-Sang Kim, Robert J Fletterick, Aaron Diaz, John S Schneekloth Jr, Holly A Ingraham
Publikováno v:
eLife, Vol 4 (2015)
SUMO-modification of nuclear proteins has profound effects on gene expression. However, non-toxic chemical tools that modulate sumoylation in cells are lacking. Here, to identify small molecule sumoylation inhibitors we developed a cell-based screen
Externí odkaz:
https://doaj.org/article/7fcdc3aaa9fb4a71988d03b8b7445de9
Autor:
Julie Hunkapiller, Yin Shen, Aaron Diaz, Gerard Cagney, David McCleary, Miguel Ramalho-Santos, Nevan Krogan, Bing Ren, Jun S Song, Jeremy F Reiter
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002576 (2012)
Polycomb repressive complex 2 (PRC2) trimethylates lysine 27 of histone H3 (H3K27me3) to regulate gene expression during diverse biological transitions in development, embryonic stem cell (ESC) differentiation, and cancer. Here, we show that Polycomb
Externí odkaz:
https://doaj.org/article/98757e8406d4491a99381d58e6311d59
Autor:
Isha Mondal, Oishika Das, Raymond Sun, Jian Gao, Bohyeon Yu, Aaron Diaz, Jinan Behnan, Abhishek Dubey, Zhipeng Meng, Emad Eskandar, Beisi Xu, Rongze Olivia. Lu, Winson S. Ho
Publikováno v:
Cancer Research.
Glioblastoma (GBM) is an immunologically “cold” tumor that does not respond to current immunotherapy. Here, we demonstrate a fundamental role for the α-isoform of the catalytic subunit of protein phosphatase-2A (PP2Ac) in regulating glioma immun
Autor:
Mendiburo, Aarón Díaz
Publikováno v:
In Norteamérica January-June 2015 10(1):229-236
Autor:
Emiliano De la Torre Pacheco M.D., Mariana Mercado Bracho M.D., Aaron Diaz Navar M.D., Francisco López Olivera Leyva M.D., Emilio Chavez Uriarte M.D., Jaime Villarreal Estrada M.D.
Background: Ileal perforation after electrical burn is a rare but serious complication that leads to high morbidity and mortality if there is a delay in diagnosis and management. We present a 50-year-old male who presented an electrical burn after ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6889bafd8932e23c7e042c9f94c37659
Autor:
Mendiburo, Aarón Díaz
Publikováno v:
In Norteamérica July-December 2014 9(2):33-58