Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Aaron D. Viny"'
Autor:
Vianne R. Gao, Rui Yang, Arnav Das, Renhe Luo, Hanzhi Luo, Dylan R. McNally, Ioannis Karagiannidis, Martin A. Rivas, Zhong-Min Wang, Darko Barisic, Alireza Karbalayghareh, Wilfred Wong, Yingqian A. Zhan, Christopher R. Chin, William S. Noble, Jeff A. Bilmes, Effie Apostolou, Michael G. Kharas, Wendy Béguelin, Aaron D. Viny, Danwei Huangfu, Alexander Y. Rudensky, Ari M. Melnick, Christina S. Leslie
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Identifying cell-type-specific 3D chromatin interactions between regulatory elements can help decipher gene regulation and interpret disease-associated non-coding variants. However, achieving this resolution with current 3D genomics technolo
Externí odkaz:
https://doaj.org/article/9058f5eecd4a4599ae65bc3feace0303
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 3, Pp 337-347 (2021)
Acute myeloid leukemia (AML) affects tens of thousands of patients a year, yet survival rates are as low as 25% in certain populations. This poor survival rate is partially due to the vast genetic diversity of the disease. Rarely do 2 patients with A
Externí odkaz:
https://doaj.org/article/2965a902d6aa4590ab37676161280f27
Autor:
Katelyn E. Heimbruch, Joseph B. Fisher, Cary T. Stelloh, Emily Phillips, Michael H. Reimer, Adam J. Wargolet, Alison E. Meyer, Kirthi Pulakanti, Aaron D. Viny, Jessica J. Loppnow, Ross L. Levine, John Anto Pulikkan, Nan Zhu, Sridhar Rao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Acute myeloid leukemia (AML) is a high-risk malignancy characterized by a diverse spectrum of somatic genetic alterations. The mechanisms by which these mutations contribute to leukemia development and how this informs the use of targeted th
Externí odkaz:
https://doaj.org/article/4bea0347dc9d49beb5298d2cdd70741f
Autor:
Martin A. Rivas, Ceyda Durmaz, Andreas Kloetgen, Cristopher R. Chin, Zhengming Chen, Bhavneet Bhinder, Amnon Koren, Aaron D. Viny, Christopher D. Scharer, Jeremy M. Boss, Olivier Elemento, Christopher E. Mason, Ari M. Melnick
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The cohesin complex plays critical roles in genomic stability and gene expression through effects on 3D architecture. Cohesin core subunit genes are mutated across a wide cross-section of cancers, but not in germinal center (GC) derived lymphomas. In
Externí odkaz:
https://doaj.org/article/d81425a378284c1c898ba5565c38ac34
Autor:
Brian M. Barth, Weiyuan Wang, Paul T. Toran, Todd E. Fox, Charyguly Annageldiyev, Regina M. Ondrasik, Nicole R. Keasey, Timothy J. Brown, Viola G. Devine, Emily C. Sullivan, Andrea L. Cote, Vasiliki Papakotsi, Su-Fern Tan, Sriram S. Shanmugavelandy, Tye G. Deering, David B. Needle, Stephan T. Stern, Junjia Zhu, Jason Liao, Aaron D. Viny, David J. Feith, Ross L. Levine, Hong-Gang Wang, Thomas P. Loughran, Jr, Arati Sharma, Mark Kester, David F. Claxton
Publikováno v:
Blood Advances, Vol 3, Iss 17, Pp 2598-2603 (2019)
Externí odkaz:
https://doaj.org/article/c4625d35b02b4dee8bf8588d9b18b16d
Autor:
Wenbin Xiao, Aaron D. Goldberg, Christopher A. Famulare, Sean M. Devlin, Nghia T. Nguyen, Sinnifer Sim, Charlene C. Kabel, Minal A. Patel, Erin M. McGovern, Akshar Patel, Jessica Schulman, Andrew J. Dunbar, Zachary D. Epstein-Peterson, Kamal N. Menghrajani, Bartlomiej M. Getta, Sheng F. Cai, Mark B. Geyer, Jacob L. Glass, Justin Taylor, Aaron D. Viny, Ross L. Levine, Yanming Zhang, Sergio A. Giralt, Virginia Klimek, Martin S. Tallman, Mikhail Roshal
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
Measurable residual disease is associated with inferior outcomes in patients with acute myeloid leukemia (AML). Measurable residual disease monitoring enhances risk stratification and may guide therapeutic intervention. The European LeukemiaNet worki
Externí odkaz:
https://doaj.org/article/45ef93eeec2c4b6a887db1c08f553826
Publikováno v:
Case Reports in Rheumatology, Vol 2018 (2018)
Familial Mediterranean fever (FMF) is an inherited disease caused by loss of function mutations in the MEFV gene encoding pyrin, a negative regulator of interleukin-1. The disease is characterized by recurrent fever and self-limited attacks of joint,
Externí odkaz:
https://doaj.org/article/35f61cae17cf4dbfb9e7406fc5a5f7e7
Autor:
Nicole Kucine, Aaron D. Viny, Raajit Rampal, Michael Berger, Nicholas Socci, Agnes Viale, James B. Bussel, Ross L. Levine, Franck Rapaport
Publikováno v:
Haematologica, Vol 101, Iss 6 (2016)
Externí odkaz:
https://doaj.org/article/499d4680b6a04c798e3cd1f98dcaaea7
Autor:
Aaron D. Viny, Michael J. Clemente, Monika Jasek, Medhat Askar, Hemant Ishwaran, Amy Nowacki, Aiwen Zhang, Jaroslaw P. Maciejewski
Publikováno v:
Haematologica, Vol 95, Iss 10 (2010)
Background Large granular lymphocyte leukemia is a semi-autonomous clonal proliferation of cytotoxic T cells accompanied by immune cytopenias and various autoimmune conditions. Due to the rarity of this disease and its association with autoimmune dis
Externí odkaz:
https://doaj.org/article/3d7960d4f001455abd47c30a6f6edea3
Autor:
Maximilian Stahl, Andriy Derkach, Noushin Farnoud, Jan Philipp Bewersdorf, Troy Robinson, Christopher Famulare, Christina Cho, Sean Devlin, Kamal Menghrajani, Minal A. Patel, Sheng F. Cai, Linde A. Miles, Robert L. Bowman, Mark B. Geyer, Andrew Dunbar, Zachary D. Epstein‐Peterson, Erin McGovern, Jessica Schulman, Jacob L. Glass, Justin Taylor, Aaron D. Viny, Eytan M. Stein, Bartlomiej Getta, Maria E. Arcila, Qi Gao, Juliet Barker, Brian C. Shaffer, Esperanza B. Papadopoulos, Boglarka Gyurkocza, Miguel‐Angel Perales, Omar Abdel‐Wahab, Ross L. Levine, Sergio A. Giralt, Yanming Zhang, Wenbin Xiao, Nidhi Pai, Elli Papaemmanuil, Martin S. Tallman, Mikhail Roshal, Aaron D. Goldberg
Publikováno v:
American Journal of Hematology. 98:79-89
Measurable residual disease (MRD) is a powerful prognostic factor in acute myeloid leukemia (AML). However, pre-treatment molecular predictors of immunophenotypic MRD clearance remain unclear. We analyzed a dataset of 211 patients with pre-treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4809b6a39e2e5c18436cf54a982f8f2b
https://doi.org/10.1002/ajh.26757
https://doi.org/10.1002/ajh.26757