Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Aaron D. Bossler"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundExon 20 (ex20) in-frame insertions or duplications (ins/dup) in epidermal growth factor receptor (EGFR) and its analog erb-b2 receptor tyrosine kinase 2 (ERBB2) are each detected in 1.5% of non–small cell lung cancer (NSCLC). Unlike EGFR
Externí odkaz:
https://doaj.org/article/dcaa01430e4a4de0b6ad039da4f3b63e
Autor:
Muhammad Furqan, Taher Abu-Hejleh, Laura M. Stephens, Stacey M. Hartwig, Sarah L. Mott, Casey F. Pulliam, Michael Petronek, John B. Henrich, Melissa A. Fath, Jon C. Houtman, Steven M. Varga, Kellie L. Bodeker, Aaron D. Bossler, Andrew M. Bellizzi, Jun Zhang, Varun Monga, Hariharasudan Mani, Marina Ivanovic, Brian J. Smith, Margaret M. Byrne, William Zeitler, Brett A. Wagner, Garry R. Buettner, Joseph J. Cullen, John M. Buatti, Douglas R. Spitz, Bryan G. Allen
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102318- (2022)
Purpose: Platinum-based chemotherapy with or without immunotherapy is the mainstay of treatment for advanced stage non-small cell lung cancer (NSCLC) lacking a molecular driver alteration. Pre-clinical studies have reported that pharmacological ascor
Externí odkaz:
https://doaj.org/article/3029ad560b984a928c853c72d0650fca
Autor:
Kevin Cheung, Aaron D. Bossler, Sarah L. Mott, Megan Zeisler, Julie McKillip, Yousef Zakharia, Brian L. Swick, Jennifer G. Powers
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
To improve understanding of the genetic signature of early-stage melanomas in Veterans, hotspot mutation profiling using next-generation sequencing (NGS) was performed on melanoma tissue samples from patients at the Iowa City Veterans Affairs Medical
Externí odkaz:
https://doaj.org/article/94645381cbcf478cb50e2dbeaa1a1c2a
Publikováno v:
Human Pathology Reports, Vol 27, Iss , Pp 300582- (2022)
The 5th edition of the WHO classification of Soft Tissue and Bone tumors recognizes lipoblastoma as a benign adipocytic tumor with excellent prognosis and a recurrence rate of 13–46%. The characteristic genomic alteration that helps separate lipobl
Externí odkaz:
https://doaj.org/article/bec17b865b7d48ccbce903eb4c29f4a3
Autor:
Austin A. Larson, Peter R. Baker, Miroslav P. Milev, Craig A. Press, Ronald J. Sokol, Mary O. Cox, Jacqueline K. Lekostaj, Aaron A. Stence, Aaron D. Bossler, Jennifer M. Mueller, Keshika Prematilake, Thierry Fotsing Tadjo, Charles A. Williams, Michael Sacher, Steven A. Moore
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background Transport protein particle (TRAPP) is a supramolecular protein complex that functions in localizing proteins to the Golgi compartment. The TRAPPC11 subunit has been implicated in muscle disease by virtue of homozygous and compound
Externí odkaz:
https://doaj.org/article/34eec2f6491f4e40885be0912b53e061
Autor:
Kim A. Brogden, Deepak Parashar, Andrea R. Hallier, Terry Braun, Fang Qian, Naiyer A. Rizvi, Aaron D. Bossler, Mohammed M. Milhem, Timothy A. Chan, Taher Abbasi, Shireen Vali
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background Programmed Death Ligand 1 (PD-L1) is a co-stimulatory and immune checkpoint protein. PD-L1 expression in non-small cell lung cancers (NSCLC) is a hallmark of adaptive resistance and its expression is often used to predict the outc
Externí odkaz:
https://doaj.org/article/5b7c0066d3c74f23970d90eaf7ec7bec
Autor:
John M. Rieth, Umang Swami, Sarah L. Mott, Mario Zanaty, Michael D. Henry, Aaron D. Bossler, Jeremy D. Greenlee, Yousef Zakharia, Marion Vanneste, Brooke Jennings, Mohammed M. Milhem
Publikováno v:
Cancers, Vol 13, Iss 7, p 1489 (2021)
Brain metastases commonly develop in melanoma and are associated with poor overall survival of about five to nine months. Fortunately, new therapies, including immune checkpoint inhibitors and BRAF/MEK inhibitors, have been developed. The aim of this
Externí odkaz:
https://doaj.org/article/c0236969886c41e6a7e0ec0912a1890f
Autor:
Umang Swami, Adithya Chennamadhavuni, Nicholas Borcherding, Aaron D. Bossler, Sarah L. Mott, Rohan Garje, Yousef Zakharia, Mohammed Milhem
Publikováno v:
Antibiotics, Vol 9, Iss 11, p 740 (2020)
Recently antibiotic exposure has been associated with worse outcomes in patients undergoing treatment with antibodies directed against programmed cell death protein-1 (PD-1). We reviewed data of 1264 patients enrolled at Melanoma Skin and Ocular Tiss
Externí odkaz:
https://doaj.org/article/84ce59a7f372487eb5211a5bd898c6fe
Autor:
Kim A. Brogden, Deepak Parashar, Andrea R. Hallier, Terry Braun, Fang Qian, Naiyer A. Rizvi, Aaron D. Bossler, Mohammed M. Milhem, Timothy A. Chan, Taher Abbasi, Shireen Vali
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-1 (2018)
Abstract It has been highlighted that in the original manuscript [1] Table S3 ‘An example of the predictive computational modeling process. Specific details on an annexure section of the PD-L1 pathway show the step-by-step reactions, mechanisms, an
Externí odkaz:
https://doaj.org/article/2ddeeb35995842d88abc16cb96811584