Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Aaron D Hernday"'
Autor:
Ruihao Li, Jordan C Rozum, Morgan M Quail, Mohammad N Qasim, Suzanne S Sindi, Clarissa J Nobile, Réka Albert, Aaron D Hernday
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1010991 (2023)
Genetic regulatory networks (GRNs) regulate the flow of genetic information from the genome to expressed messenger RNAs (mRNAs) and thus are critical to controlling the phenotypic characteristics of cells. Numerous methods exist for profiling mRNA tr
Externí odkaz:
https://doaj.org/article/123eb2a399af4c0a8e21b32cf070d08e
Autor:
Thaddeus D Seher, Namkha Nguyen, Diana Ramos, Priyanka Bapat, Clarissa J Nobile, Suzanne S Sindi, Aaron D Hernday
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 9 (2021)
AbstractCRISPR/Cas-induced genome editing is a powerful tool for genetic engineering, however, targeting constraints limit which loci are editable with this method. Since the length of a DNA sequence impacts the likelihood it overlaps a unique target
Externí odkaz:
https://doaj.org/article/bd5dcecd14504b02be8e696e95152d11
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003210 (2013)
The ability to switch between yeast and filamentous forms is central to Candida albicans biology. The yeast-hyphal transition is implicated in adherence, tissue invasion, biofilm formation, phagocyte escape, and pathogenesis. A second form of morphol
Externí odkaz:
https://doaj.org/article/ad1adb734da6471d93b7aeb2a04c129b
Autor:
Jing Xie, Li Tao, Clarissa J Nobile, Yaojun Tong, Guobo Guan, Yuan Sun, Chengjun Cao, Aaron D Hernday, Alexander D Johnson, Lixin Zhang, Feng-Yan Bai, Guanghua Huang
Publikováno v:
PLoS Biology, Vol 11, Iss 3, p e1001525 (2013)
Phenotypic transitions play critical roles in host adaptation, virulence, and sexual reproduction in pathogenic fungi. A minority of natural isolates of Candida albicans, which are homozygous at the mating type locus (MTL, a/a or α/α), are known to
Externí odkaz:
https://doaj.org/article/8552ba6072fd4e6693325686041714a9
Autor:
Brian B Tuch, Quinn M Mitrovich, Oliver R Homann, Aaron D Hernday, Cinna K Monighetti, Francisco M De La Vega, Alexander D Johnson
Publikováno v:
PLoS Genetics, Vol 6, Iss 8, p e1001070 (2010)
The differentiation of cells into distinct cell types, each of which is heritable for many generations, underlies many biological phenomena. White and opaque cells of the fungal pathogen Candida albicans are two such heritable cell types, each though
Externí odkaz:
https://doaj.org/article/615cf890f5d94e6a882187ded0329f96
Autor:
Clarissa J Nobile, Jeniel E Nett, Aaron D Hernday, Oliver R Homann, Jean-Sebastien Deneault, Andre Nantel, David R Andes, Alexander D Johnson, Aaron P Mitchell
Publikováno v:
PLoS Biology, Vol 7, Iss 6, p e1000133 (2009)
A biofilm is a surface-associated population of microorganisms embedded in a matrix of extracellular polymeric substances. Biofilms are a major natural growth form of microorganisms and the cause of pervasive device-associated infection. This report
Externí odkaz:
https://doaj.org/article/ad136d62b4264889b5cada28f1c3bc01
Publikováno v:
PLoS Biology, Vol 6, Iss 2, p e38 (2008)
It is widely suspected that gene regulatory networks are highly plastic. The rapid turnover of transcription factor binding sites has been predicted on theoretical grounds and has been experimentally demonstrated in closely related species. We combin
Externí odkaz:
https://doaj.org/article/f036d69329d147cfbd9d554969bc1d9a
Autor:
Karen A. Conrad, Hyunjeong Kim, Mohammad Qasim, Amel Djehal, Aaron D. Hernday, Laurent Désaubry, Jason M. Rauceo
Publikováno v:
Pathogens; Volume 12; Issue 1; Pages: 126
Pathogens
Pathogens, 2023, 12 (1), pp.126. ⟨10.3390/pathogens12010126⟩
Pathogens
Pathogens, 2023, 12 (1), pp.126. ⟨10.3390/pathogens12010126⟩
Invasive fungal infections caused by Candida species remain a significant public health problem worldwide. The increasing prevalence of drug-resistant infections and a limited arsenal of antifungal drugs underscore the need for novel interventions. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac5a66f4734132ed1833250c534069b
https://www.mdpi.com/2076-0817/12/1/126
https://www.mdpi.com/2076-0817/12/1/126
Autor:
Aaron D. Hernday, Clarissa J. Nobile, Suzanne S. Sindi, Craig L. Ennis, Akshay D. Paropkari, Ashley Valle Arevalo, Mohammad N. Qasim
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254479ce33a6df7952aeddd72d87087b
https://doi.org/10.3791/63655
https://doi.org/10.3791/63655
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
Microbiology spectrum, vol 9, iss 3
Microbiology Spectrum
Microbiology spectrum, vol 9, iss 3
Microbiology Spectrum
Candida auris is a multidrug-resistant human fungal pathogen that has recently emerged worldwide. It can cause life-threatening disseminated infections in humans, with mortality rates upwards of 50%. The molecular mechanisms underlying its multidrug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e0c06432924ef254fa5a5c2767850e
https://journals.asm.org/doi/10.1128/Spectrum.01820-21
https://journals.asm.org/doi/10.1128/Spectrum.01820-21