Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Aaron D, Hernday"'
Autor:
Ruihao Li, Jordan C Rozum, Morgan M Quail, Mohammad N Qasim, Suzanne S Sindi, Clarissa J Nobile, Réka Albert, Aaron D Hernday
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1010991 (2023)
Genetic regulatory networks (GRNs) regulate the flow of genetic information from the genome to expressed messenger RNAs (mRNAs) and thus are critical to controlling the phenotypic characteristics of cells. Numerous methods exist for profiling mRNA tr
Externí odkaz:
https://doaj.org/article/123eb2a399af4c0a8e21b32cf070d08e
Autor:
Karen A. Conrad, Hyunjeong Kim, Mohammad Qasim, Amel Djehal, Aaron D. Hernday, Laurent Désaubry, Jason M. Rauceo
Publikováno v:
Pathogens, Vol 12, Iss 1, p 126 (2023)
Invasive fungal infections caused by Candida species remain a significant public health problem worldwide. The increasing prevalence of drug-resistant infections and a limited arsenal of antifungal drugs underscore the need for novel interventions. H
Externí odkaz:
https://doaj.org/article/526376f0a0d9415ea385864e2868926d
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT Candida auris is a multidrug-resistant human fungal pathogen that has recently emerged worldwide. It can cause life-threatening disseminated infections in humans, with mortality rates upwards of 50%. The molecular mechanisms underlying its m
Externí odkaz:
https://doaj.org/article/c87d273ebce6428bb2be7c866b50c945
Autor:
Thaddeus D Seher, Namkha Nguyen, Diana Ramos, Priyanka Bapat, Clarissa J Nobile, Suzanne S Sindi, Aaron D Hernday
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 9 (2021)
AbstractCRISPR/Cas-induced genome editing is a powerful tool for genetic engineering, however, targeting constraints limit which loci are editable with this method. Since the length of a DNA sequence impacts the likelihood it overlaps a unique target
Externí odkaz:
https://doaj.org/article/bd5dcecd14504b02be8e696e95152d11
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Candida albicans is a commensal member of the human microbiota that colonizes multiple niches in the body including the skin, oral cavity, and gastrointestinal and genitourinary tracts of healthy individuals. It is also the most common human fungal p
Externí odkaz:
https://doaj.org/article/f9fb9ac62c054d9abad91db3f9478574
Publikováno v:
Journal of Fungi, Vol 7, Iss 1, p 37 (2021)
Candida albicans, a diploid polymorphic fungus, has evolved a unique heritable epigenetic program that enables reversible phenotypic switching between two cell types, referred to as “white” and “opaque”. These cell types are established and m
Externí odkaz:
https://doaj.org/article/d404b5073b5440238d3869893a976832
Publikováno v:
Journal of Fungi, Vol 6, Iss 3, p 129 (2020)
The sensing and efficient utilization of environmental nutrients are critical for the survival of microorganisms in environments where nutrients are limited, such as within mammalian hosts. Candida albicans is a common member of the human microbiota
Externí odkaz:
https://doaj.org/article/e224103e60ff4f0d8d07b47b590a554f
Publikováno v:
Journal of Fungi, Vol 6, Iss 1, p 14 (2020)
Biofilms, structured and densely packed communities of microbial cells attached to surfaces, are considered to be the natural growth state for a vast majority of microorganisms. The ability to form biofilms is an important virulence factor for most p
Externí odkaz:
https://doaj.org/article/a4424f9569e642fb94afe2af6b97ebca
Publikováno v:
mSphere, Vol 2, Iss 2 (2017)
ABSTRACT Candida albicans is the most common fungal pathogen of humans. Historically, molecular genetic analysis of this important pathogen has been hampered by the lack of stable plasmids or meiotic cell division, limited selectable markers, and ine
Externí odkaz:
https://doaj.org/article/f4dc70938e6b4a3f9c720f58bed2963e
Autor:
Aaron D. Hernday, Clarissa J. Nobile, Suzanne S. Sindi, Craig L. Ennis, Akshay D. Paropkari, Ashley Valle Arevalo, Mohammad N. Qasim
Publikováno v:
Journal of Visualized Experiments.