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pro vyhledávání: '"Aaron Chanas-Larue"'
Autor:
James B. Johnston, Elizabeth S. Henson, Aaron Chanas-Larue, Spencer B. Gibson, Gloria E. Villalpando-Rodriguez
Publikováno v:
Leukemia research. 96
Lysosomes in chronic lymphocytic leukemia (CLL) cells have previously been identified as a promising target for therapeutic intervention in combination with targeted therapies. Recent studies have shown that antihistamines can induce lysosomal membra
Autor:
Spencer B. Gibson, Rebecca Dielschneider, James B. Johnston, Subhadip Das, Aaron Chanas-Larue
Publikováno v:
Leukemia Research. 70:79-86
Lysosomes are the most acidic vesicles within mammalian cells and are promising targets for the treatment of breast cancer, glioblastomas and acute myeloid leukemia (AML). Our previous studies have shown that chronic lymphocytic leukemia (CLL) cells
Publikováno v:
Cancer Research. 78:3976-3976
Chronic Lymphocytic Leukemia (CLL) is a B-cell derived cancer and is the most commonly diagnosed leukemia in older adults. Several survival signals contribute to the accumulation of CLL cells including constitutive activation the B-cell receptor (BCR