Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Aaron B. Bogutz"'
Autor:
Kentaro Mochizuki, Jafar Sharif, Kenjiro Shirane, Kousuke Uranishi, Aaron B. Bogutz, Sanne M. Janssen, Ayumu Suzuki, Akihiko Okuda, Haruhiko Koseki, Matthew C. Lorincz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Germline genes are repressed by DNA methylation and histone marks. Here, the authors show that specific germline genes hypomethylated pre-implantation are enriched for PRC1.6, H2AK119ub1 and H3K9me3, which coordinately repress their expression.
Externí odkaz:
https://doaj.org/article/006b6218cf214219b0b8f0d42574bd86
Autor:
Takamasa Ito, Musashi Kubiura-Ichimaru, Yuri Murakami, Aaron B. Bogutz, Louis Lefebvre, Isao Suetake, Shoji Tajima, Masako Tada
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
DNA methylation (DNAme; 5-methylcytosine, 5mC) plays an essential role in mammalian development, and the 5mC profile is regulated by a balance of opposing enzymatic activities: DNA methyltransferases (DNMTs) and Ten-eleven translocation dioxygenases
Externí odkaz:
https://doaj.org/article/99641d88b0f941718b248c99fdd478dc
Autor:
Aaron B. Bogutz, Julie Brind’Amour, Hisato Kobayashi, Kristoffer N. Jensen, Kazuhiko Nakabayashi, Hiroo Imai, Matthew C. Lorincz, Louis Lefebvre
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Although many species-specific imprinted genes have been identified, how the evolutionary switch from biallelic to imprinted expression occurs is still unknown. Here authors find that lineage-specific ERVs active as oocyte promoters can induce de nov
Externí odkaz:
https://doaj.org/article/23eab72a42084803b96998d94acb4a07
Autor:
Julien Richard Albert, Tasuku Koike, Hamid Younesy, Richard Thompson, Aaron B. Bogutz, Mohammad M. Karimi, Matthew C. Lorincz
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-19 (2018)
Abstract Background Allele-specific transcriptional regulation, including of imprinted genes, is essential for normal mammalian development. While the regulatory regions controlling imprinted genes are associated with DNA methylation (DNAme) and spec
Externí odkaz:
https://doaj.org/article/f26e4823969c49ed9bdf9abec90c6f27
Autor:
Akihiko Okuda, Ayumu Suzuki, Kentaro Mochizuki, Kenjiro Shirane, Haruhiko Koseki, Kousuke Uranishi, Aaron B. Bogutz, Jafar Sharif, Matthew C. Lorincz, Sanne M. Janssen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Silencing of a subset of germline genes is dependent upon DNA methylation (DNAme) post-implantation. However, these genes are generally hypomethylated in the blastocyst, implicating alternative repressive pathways before implantation. Indeed, in embr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfe3e3a5f168ba1ac4cb64125ae8894
https://doaj.org/article/006b6218cf214219b0b8f0d42574bd86
https://doaj.org/article/006b6218cf214219b0b8f0d42574bd86
Autor:
Julien Richard Albert, Wan Kin Au Yeung, Hiroyuki Sasaki, Aaron B. Bogutz, Keisuke Toriyama, Matthew C. Lorincz, Hisato Kobayashi, Ryutaro Hirasawa, Julie Brind’Amour
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
De novo DNA methylation (DNAme) during mammalian spermatogenesis yields a densely methylated genome, with the exception of CpG islands (CGIs), which are hypomethylated in sperm. While the paternal genome undergoes widespread DNAme loss before the fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4218426f8c004f8a54f660b3732ec83a
https://doaj.org/article/128797e6956e467bae7bb0618d815a9b
https://doaj.org/article/128797e6956e467bae7bb0618d815a9b
Autor:
Ivan Sadowski, Aaron B. Bogutz
Publikováno v:
BioTechniques. 69(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a15ff77690e4d3f42699603e2be8341
https://pubmed.ncbi.nlm.nih.gov/33228394
https://pubmed.ncbi.nlm.nih.gov/33228394
Autor:
Julien Richard Albert, Hisato Kobayashi, Keisuke Toriyama, Wan Kin Au Yeung, Julie Brind’Amour, Matthew C. Lorincz, Hiroyuki Sasaki, Aaron B. Bogutz, Ryutaro Hirasawa
De novo DNA methylation (DNAme) during mammalian spermatogenesis yields a densely methylated genome, with the exception of CpG islands (CGIs), which are hypomethylated in sperm. Following fertilization, the paternal genome undergoes widespread DNAme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c8e8ca8a7696e5dfa62bcb9752ea6e
https://doi.org/10.1101/2020.03.26.009977
https://doi.org/10.1101/2020.03.26.009977
Autor:
Matthew C. Lorincz, Hiroo Imai, Hisato Kobayashi, Louis Lefebvre, Kazuhiko Nakabayashi, Julie Brind’Amour, Kristoffer N. Jensen, Aaron B. Bogutz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Imprinted genes are expressed from a single parental allele, with the other allele often silenced by DNA methylation (DNAme) established in the germline. While species-specific imprinted orthologues have been documented, the molecular mechanisms unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be94babcccbc08a2845983a23eb3aa6a
https://doi.org/10.1038/s41467-019-13662-9
https://doi.org/10.1038/s41467-019-13662-9
Autor:
Bhavya Venkatesh, Amanda Haage, Caitlin Mitchell, Aaron B. Bogutz, Catherine D. Van Raamsdonk, Louis Lefebvre, Guy Tanentzapf, Wenjun Deng, Kelsey Wagner, Katharine Goodwin
Publikováno v:
Development (Cambridge, England). 147(14)
Melanoblasts disperse throughout the skin and populate hair follicles through long-range cell migration. During migration, cells undergo cycles of coordinated attachment and detachment from the Extra-Cellular Matrix (ECM). Embryonic migration process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e61678c5f1a9b3db0fdd12cb70b5840
https://pubmed.ncbi.nlm.nih.gov/32580934
https://pubmed.ncbi.nlm.nih.gov/32580934