Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Aaron B Morton"'
Autor:
Kurt J Sollanek, Jatin G Burniston, Andreas N Kavazis, Aaron B Morton, Michael P Wiggs, Bumsoo Ahn, Ashley J Smuder, Scott K Powers
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0171007 (2017)
Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, prolonged MV results in the rapid development of diaphragmatic atrophy and weakness. Importantly, endurance exercise training results in a diap
Externí odkaz:
https://doaj.org/article/8cf0b63be931476caa141b57912096f6
Autor:
Patrick J. Ryan, Selina Uranga, Sean T. Stanelle, Megan H. Lewis, Colleen L. O’Reilly, Jessica M. Cardin, J. William Deaver, Aaron B. Morton, James D. Fluckey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The mammalian target of rapamycin (mTOR), and specifically the mTOR complex 1 (mTORC1) is the central regulator of anabolism in skeletal muscle. Among the many functions of this kinase complex is the inhibition of the catabolic process of au
Externí odkaz:
https://doaj.org/article/b60b8b98c6a8486fa42bf4074924f521
Publikováno v:
Skeletal Muscle, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Background Acute injury to skeletal muscle damages myofibers and fragment capillaries, impairing contractile function and local perfusion. Myofibers and microvessels regenerate from satellite cells and from surviving microvessel fragments, r
Externí odkaz:
https://doaj.org/article/10e6b44d88254f3ebdff90fcad9cbb25
Autor:
Noriko Ichinoseki‐Sekine, Ashley J. Smuder, Aaron B. Morton, James M. Hinkley, Andres Mor Huertas, Scott K. Powers
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 6, Pp 2139-2145 (2021)
Abstract Mechanical ventilation (MV) is a clinical tool providing adequate alveolar ventilation in patients that require respiratory support. Although a life‐saving intervention for critically ill patients, prolonged MV results in the rapid develop
Externí odkaz:
https://doaj.org/article/7d170cf563a6460aa9f8669b55a66868
Autor:
Stephanie E. Hall, Bumsoo Ahn, Ashley J. Smuder, Aaron B. Morton, J. Matthew Hinkley, Michael P. Wiggs, Kurt J. Sollanek, Hayden Hyatt, Scott K. Powers
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 2, Pp 481-486 (2021)
Mechanical ventilation (MV) is a life‐saving intervention for many critically ill patients. Unfortunately, prolonged MV results in the rapid development of inspiratory muscle weakness due to diaphragmatic atrophy and contractile dysfunction (termed
Externí odkaz:
https://doaj.org/article/c3a90701f29349d0b55040dbe124d970
Autor:
Aaron B. Morton, Charles E. Norton, Nicole L. Jacobsen, Charmain A. Fernando, D. D. W. Cornelison, Steven S. Segal
Publikováno v:
Skeletal Muscle, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Background Local injection of BaCl2 is an established model of acute injury to study the regeneration of skeletal muscle. However, the mechanism by which BaCl2 causes muscle injury is unresolved. Because Ba2+ inhibits K+ channels, we hypothe
Externí odkaz:
https://doaj.org/article/75dc1513bd7544928f2446c4fda39ba7
Autor:
Ashley J. Smuder, Aaron B. Morton, Stephanie E. Hall, Michael P. Wiggs, Bumsoo Ahn, Nicholas R. Wawrzyniak, Kurt J. Sollanek, Kisuk Min, Oh Sung Kwon, W. Bradley Nelson, Scott K. Powers
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 4, Pp 767-781 (2019)
Abstract Background Mechanical ventilation (MV) is a life‐saving measure for patients in respiratory failure. However, prolonged MV results in significant diaphragm atrophy and contractile dysfunction, a condition referred to as ventilator‐induce
Externí odkaz:
https://doaj.org/article/0ef51348f7ce49edbbf5cbde5d8d4b76
Autor:
Aaron B. Morton, Ashley J. Smuder, Michael P. Wiggs, Stephanie E. Hall, Bumsoo Ahn, J. Matthew Hinkley, Noriko Ichinoseki-Sekine, Andres Mor Huertas, Mustafa Ozdemir, Toshinori Yoshihara, Nicholas R. Wawrzyniak, Scott K. Powers
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 402-413 (2019)
Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, prolonged MV results in rapid diaphragmatic atrophy and contractile dysfunction, collectively termed ventilator-induced diaphragm dysfunction (
Externí odkaz:
https://doaj.org/article/65091f6caf7e47ae9b34c6082630e30b
Autor:
Ashley J. Smuder, Sara M. Turner, Cassandra M. Schuster, Aaron B. Morton, J. Matthew Hinkley, David D. Fuller
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7219 (2020)
Oxidative damage to the diaphragm as a result of cervical spinal cord injury (SCI) promotes muscle atrophy and weakness. Respiratory insufficiency is the leading cause of morbidity and mortality in cervical spinal cord injury (SCI) patients, emphasiz
Externí odkaz:
https://doaj.org/article/35cbc3a8d48a43a8b40bcc5f8e2129b5
Autor:
Scott K. Powers, Noriko Ichinoseki-Sekine, Ashley J. Smuder, James Matthew Hinkley, Aaron B. Morton, Andres Mor Huertas
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 6, Pp 2139-2145 (2021)
Clinical and Translational Science, Vol 14, Iss 6, Pp 2139-2145 (2021)
Mechanical ventilation (MV) is a clinical tool providing adequate alveolar ventilation in patients that require respiratory support. Although a life-saving intervention for critically ill patients, prolonged MV results in the rapid development of ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3721e4fff8914466dc2d89492c03dac2
http://europepmc.org/articles/PMC8604213
http://europepmc.org/articles/PMC8604213