Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Aaron Adamson"'
Autor:
Jessica Clague, Greg Wilhoite, Aaron Adamson, Adam Bailis, Jeffrey N Weitzel, Susan L Neuhausen
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25632 (2011)
BRCA1 and BRCA2 are the most well-known breast cancer susceptibility genes. Additional genes involved in DNA repair have been identified as predisposing to breast cancer. One such gene, RAD51C, is essential for homologous recombination repair. Severa
Externí odkaz:
https://doaj.org/article/2efed9ff9673472c86959d1c1b0ecae8
Autor:
Rossana Rico, Adam M. Bailis, Aaron Adamson, Isabelle Y. Lopez, J. Jefferson P. Perry, M. Cristina Negritto, Olivia Lewis, Jason Xu, Nikola Kenjić, Shannon N Owens, Alissa D. Clear, Susan L. Neuhausen, Elise W. Wolf, Glenn M. Manthey
Publikováno v:
Microbial Cell, Vol 7, Iss 10, Pp 270-285 (2020)
RAD52 is a structurally and functionally conserved component of the DNA double-strand break (DSB) repair apparatus from budding yeast to humans. We recently showed that expressing the human gene, HsRAD52 in rad52 mutant budding yeast cells can suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a1a6f64c647269989dd10cced4d536
http://microbialcell.com/researcharticles/2020a-clear-microbial-cell/
http://microbialcell.com/researcharticles/2020a-clear-microbial-cell/
Autor:
Adam M. Bailis, Yuan Chun Ding, Jeremy M. Stark, Aaron Adamson, Carlos Mendez-Dorantes, Susan L. Neuhausen
Publikováno v:
Molecular Oncology, Vol 14, Iss 6, Pp 1124-1133 (2020)
Women who carry pathogenic mutations in BRCA1 and BRCA2 have a lifetime risk of developing breast cancer of up to 80%. However, risk estimates vary in part due to genetic modifiers. We investigated the association of the RAD52 S346X variant as a modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abaa055bd073038a058051bf0b7a6eb9
https://doaj.org/article/cb800f55b01b465182b712f608832d8f
https://doaj.org/article/cb800f55b01b465182b712f608832d8f
Autor:
Susan L. Neuhausen, Scott Huntsman, Eliseo J. Pérez-Stable, Aaron Adamson, Charleen D. Adams, Linda Steele, Donglei Hu, Jeffrey N. Weitzel, Jung Byun, Kevin Gardner, Elad Ziv, Shu Tao, Daniel Schmolze, Anna María Nápoles
Publikováno v:
Cancer Research. 80:P4-09
Background: Latinos represent the largest and fastest-growing minority population in the US; breast cancer is the most common cancer and causes the most cancer deaths in this population. Precision medicine is being applied increasingly to guide breas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8647f4edd1b379cb8b2016d92733bbf1
https://doi.org/10.1158/1538-7445.sabcs19-p4-09-02
https://doi.org/10.1158/1538-7445.sabcs19-p4-09-02
Autor:
Nancy Feldman, Aaron Adamson, Sharon Sand, Charité Ricker, Thomas P. Slavin, Christopher A. Haiman, Scott Huntsman, Jeffrey N. Weitzel, Amie Blanco, Susan L. Neuhausen, Danielle Castillo, Shu Tao, Donglei Hu, Linda Steele, Asaf Maoz, Gary Unzeitig, Bita Nehoray, Elad Ziv, Margalit Rosenblatt
Publikováno v:
Cancer. 125:2829-2836
BACKGROUND Breast cancer (BC) is the most common cancer and related cause of mortality among Hispanics, yet susceptibility has been understudied. BRCA1 and BRCA2 (BRCA) mutations explain less than one-half of hereditary BC, and the proportion associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::845a501d17d5d3b34a3fbcae3b734e9a
https://doi.org/10.1002/cncr.32083
https://doi.org/10.1002/cncr.32083
Autor:
Jovia L Nierenberg, Aaron Adamson, Yuan C. Ding, Yiwey Shieh, Donglei Hu, Scott Huntsman, Esther M. John, Gabriela Torres-Mejia, Christopher A. Haiman, Lawrence H. Kushi, Charite N. Ricker, Linda Steele, Robin Lee, Jeffrey N. Weitzel, Laura Fejerman, Elad Ziv, Susan L. Neuhausen
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 31:PO-164
Introduction: Pathogenic variants (PVs) in high- and intermediate-penetrance breast cancer susceptibility genes have large effects on disease risk. While individual PVs are rare, in aggregate, they markedly contribute to breast cancer risk in women o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c9d4339e9a0418212898116de383c5
https://doi.org/10.1158/1538-7755.disp21-po-164
https://doi.org/10.1158/1538-7755.disp21-po-164
Autor:
Gail E. Tomlinson, Yuan Chun Ding, Aaron Adamson, Susan L. Neuhausen, Esther M. John, Adam M. Bailis, Linda Steele
Publikováno v:
Familial Cancer. 17:187-195
African-American women are more likely to develop aggressive breast cancer at younger ages and experience poorer cancer prognoses than non-Hispanic Caucasians. Deficiency in repair of DNA by homologous recombination (HR) is associated with cancer dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396318c9a571150a43e4497e87881294
https://doi.org/10.1007/s10689-017-0036-4
https://doi.org/10.1007/s10689-017-0036-4
Autor:
Xiwei Wu, Ilana Solomon, Sue Nadesan, Aaron Adamson, Sharon Sand, Shu Tao, Vincent Chung, Nancy Guerrero-Llamas, Jeffrey N. Weitzel, Danielle Castillo, Susan L. Neuhausen, Thomas P. Slavin, Gagandeep Singh, Christina Rybak, Shivali Raja, Bita Nehoray, Kai Yang, Josef Herzog, Mariana Niell-Swiller, Marcia Cruz-Correa, Kathleen R. Blazer, Gloria M. Petersen, Sandra Brown
Publikováno v:
Familial Cancer. 17:235-245
Approximately 5–10% of all pancreatic cancer patients carry a predisposing mutation in a known susceptibility gene. Since >90% of patients present with late stage disease, it is crucial to identify high risk individuals who may be amenable to early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9fa8bb0a4338f8e5f689275c403f83
https://doi.org/10.1007/s10689-017-0019-5
https://doi.org/10.1007/s10689-017-0019-5
Autor:
Aaron Adamson, Elad Ziv, Jeffrey N. Weitzel, Charleen D. Adams, Kevin Gardner, Shu Tao, Eliseo J. Pérez-Stable, Linda Steele, Daniel Schmolze, Jung Byun, Anna M. Nápoles-Springer, Susan L. Neuhausen, Donglei Hu, Scott Huntsman
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:B081-B081
Background: Latinos represent the largest and fastest-growing minority population in the US; breast cancer is the most common cancer and causes the most cancer deaths in this population. Copy number amplifications and deletions are an important deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d3d81a0d199567c85c9cb98dc6b195f
https://doi.org/10.1158/1538-7755.disp19-b081
https://doi.org/10.1158/1538-7755.disp19-b081
Autor:
Jeffrey N, Weitzel, Susan L, Neuhausen, Aaron, Adamson, Shu, Tao, Charité, Ricker, Asaf, Maoz, Margalit, Rosenblatt, Bita, Nehoray, Sharon, Sand, Linda, Steele, Gary, Unzeitig, Nancy, Feldman, Amie M, Blanco, Donglei, Hu, Scott, Huntsman, Danielle, Castillo, Christopher, Haiman, Thomas, Slavin, Elad, Ziv
Publikováno v:
Cancer. 125(16)
Breast cancer (BC) is the most common cancer and related cause of mortality among Hispanics, yet susceptibility has been understudied. BRCA1 and BRCA2 (BRCA) mutations explain less than one-half of hereditary BC, and the proportion associated with ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52f4635ea150d2ab75535331bc61a6bd
https://pubmed.ncbi.nlm.nih.gov/31206622
https://pubmed.ncbi.nlm.nih.gov/31206622