Výsledky vyhledávání - "Aaron, Griffin"

DIPG-57. A systems biology approach to defining and targeting master regulator dependencies from bulk and single-Cell RNA-seq in diffuse midline glioma (DMG)

Autor: Ester Calvo Fernández, Junqiang Wang, Aaron Griffin, Hanna Minns, Hong-Jian Wei, Xu Zhang, Luca Szalontay, Prabhjot Mundi, Cheng-Chia Wu, Robyn Gartrell, Stergios Zacharoulis, Andrea Califano, Jovana Pavisic

Publikováno v: Neuro-Oncology. 24:i31-i32

Diffuse midline glioma (DMG) are fatal pediatric brain tumors with no effective systemic therapies. Molecular profiling demonstrates epigenetic dysregulation and heterogeneity, and novel approaches are needed to identify promising drugs and drug comb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0695ea2583772f83047689dfd4ce16a3
https://doi.org/10.1093/neuonc/noac079.114

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Deuteration of nonexchangeable protons on proteins affects their thermal stability, side‐chain dynamics, and hydrophobicity

Autor: Aaron Griffin, Robert S. Hodges, Parker J. Nichols, Liliya Vugmeyster, Christopher J. McKnight, Beat Vögeli, Isaac B. Falconer, Colin T. Mant

Publikováno v: Protein Sci

We have investigated the effect of deuteration of non‐exchangeable protons on protein global thermal stability, hydrophobicity, and local flexibility using well‐known thermostable model systems such as the villin headpiece subdomain (HP36) and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bb9fdd1283873977cb67841bda483e
https://europepmc.org/articles/PMC7314392/

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Autor: Parker J. Nichols, Liliya Vugmeyster, Dmitry Ostrovsky, C. James McKnight, Beat Vögeli, Shibani Bhattacharya, Aaron Griffin

Publikováno v: Journal of Biomolecular NMR. 72:39-54

We investigated correlated µs-ms time scale motions of neighboring 13C'-15N and 13Cα-13Cβ nuclei in both protonated and perdeuterated samples of GB3. The techniques employed, NMR relaxation due to cross-correlated chemical shift modulations, speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::88d403c4f4031d53052799033b02ef02
https://doi.org/10.1007/s10858-018-0205-2

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Bioremediation Strategies Aimed at Stimulating Chlorinated Solvent Dehalogenation Can Lead to Microbially-Mediated Toluene Biogenesis

Autor: J Bryan McReynolds, Samuel J Reynolds, William M. Moe, M Aaron Griffin

Publikováno v: Environmental Science & Technology. 52:9311-9319

In situ bioremediation practices that include subsurface addition of fermentable electron donors to stimulate reductive dechlorination by anaerobic bacteria have become widely employed to combat chlorinated solvent contamination in groundwater. At a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18fc50d059310c4b4718f90a7a90da1
https://doi.org/10.1021/acs.est.8b02081

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An ex vivo comparison of over-the-counter cerumenolytics for ear wax

Autor: Bernard C. S. Whitfield, Timothy Tynan, Aaron Griffin

Publikováno v: Australian Journal of Otolaryngology. 3:33-33

Background: Ear wax (cerumen) impaction is a common reason why patients present to general practitioners (GPs) and ear, nose and throat (ENT) specialists. However, there is no consensus on the effectiveness of the variety of cerumenolytics commonly a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a990347ead14542d8f7426f15f9418e2
https://doi.org/10.21037/ajo-20-50

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Correlated motions of C'-N and C

Autor: Liliya, Vugmeyster, Aaron, Griffin, Dmitry, Ostrovsky, Shibani, Bhattacharya, Parker J, Nichols, C James, McKnight, Beat, Vögeli

Publikováno v: Journal of biomolecular NMR. 72(1-2)

We investigated correlated μs-ms time scale motions of neighboring (13)C’─(15)N and (13)C(α)─(13)C(β) nuclei in both protonated and perdeuterated samples of GB3. The techniques employed, NMR relaxation due to cross-correlated chemical shift

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0fe45896c18c97db6f61d20acf531802
https://pubmed.ncbi.nlm.nih.gov/30121872

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Schneiderian-Type Papilloma of the Middle Ear: A Review of the Literature

Autor: Natalie Dixon, Peter Gochee, Nathan Schaefer, Aaron Griffin, Andrew Little, Jessica Chong

Publikováno v: International Surgery. 100:989-993

Schneiderian-type papilloma of the middle ear is a rare finding. We present a 46-year-old Aboriginal man with a large tympanic membrane perforation and a Schneiderian-type papilloma filling the middle ear. The aim of this study is to familiarize clin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbca1ed873abf0b1499b6fd2b8e4851
https://doi.org/10.9738/intsurg-d-14-00242.1

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Mastoidectomy indications and incidence in the indigenous population of Far North Queensland

Autor: Thomas Placanica, Philip Jumeau, Vibhuti Mahanta, Aaron Griffin

Publikováno v: Australian Journal of Otolaryngology. 1:24-24

Background: To review all mastoidectomies performed over a 10-year period in one tertiary hospital in Australia and evaluate the incidence and indications of operations in the Indigenous population. Methods: A retrospective review combining clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afdf81a33f0b43d52e5383896e65befc
https://doi.org/10.21037/ajo.2018.09.04

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