Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Aaron, Easterbrook"'
Autor:
Amelie V, Guitart, Theano I, Panagopoulou, Arnaud, Villacreces, Milica, Vukovic, Catarina, Sepulveda, Lewis, Allen, Roderick N, Carter, Louie N, van de Lagemaat, Marcos, Morgan, Peter, Giles, Zuzanna, Sas, Marta Vila, Gonzalez, Hannah, Lawson, Jasmin, Paris, Joy, Edwards-Hicks, Katrin, Schaak, Chithra, Subramani, Deniz, Gezer, Alejandro, Armesilla-Diaz, Jimi, Wills, Aaron, Easterbrook, David, Coman, Chi Wai Eric, So, Donal, O'Carroll, Douglas, Vernimmen, Neil P, Rodrigues, Patrick J, Pollard, Nicholas M, Morton, Andrew, Finch, Kamil R, Kranc
Publikováno v:
Guitart, A V, Panagopoulou, T I, Villacreces, A, Vukovic, M, Sepulveda, C, Allen, L, Carter, R N, van de Lagemaat, L N, Morgan, M, Giles, P, Sas, Z, Gonzalez, M V, Lawson, H, Paris, J, Edwards-Hicks, J, Schaak, K, Subramani, C, Gezer, D, Armesilla-Diaz, A, Wills, J, Easterbrook, A, Coman, D, So, C W E, O'Carroll, D, Vernimmen, D, Rodrigues, N P, Pollard, P J, Morton, N M, Finch, A & Kranc, K R 2017, ' Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions ', The Journal of experimental medicine, vol. 214, no. 3, pp. 719-735 . https://doi.org/10.1084/jem.20161087
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Guitart et al. performed an in vivo genetic dissection of the Krebs cycle enzyme fumarate hydratase (Fh1) in the hematopoietic system. Their investigations revealed multifaceted functions of Fh1 in the regulation of hematopoietic stem cell biology an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b414ecb67ecfd079f28382a9e58a2a5b
https://kclpure.kcl.ac.uk/en/publications/606e0f65-93b1-4f5f-9846-41292a145066
https://kclpure.kcl.ac.uk/en/publications/606e0f65-93b1-4f5f-9846-41292a145066
Autor:
David R. Thorburn, Aaron Easterbrook, Joyce Y Wu, Maria Panayi, Miranda Durkie, Wendy Salter, Simone Tregoning, David Coman
Publikováno v:
Twin Research and Human Genetics. 16:1117-1120
Fumarase deficiency is a rare autosomal recessive inborn error of metabolism of the Krebs Tricarboxylic Acid cycle. A heavy neurological disease burden is imparted by fumarase deficiency, commonly manifesting as microcephaly, dystonia, global develop