Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Aaron, Beach"'
Autor:
Lisa N. Kasiewicz, Souvik Biswas, Aaron Beach, Huilan Ren, Chaitali Dutta, Anne Marie Mazzola, Ellen Rohde, Alexandra Chadwick, Christopher Cheng, Sara P. Garcia, Sowmya Iyer, Yuri Matsumoto, Amit V. Khera, Kiran Musunuru, Sekar Kathiresan, Padma Malyala, Kallanthottathil G. Rajeev, Andrew M. Bellinger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Lipid nanoparticles have demonstrated utility in hepatic delivery of a range of therapeutic modalities and typically deliver their cargo via low-density lipoprotein receptor-mediated endocytosis. For patients lacking sufficient low-density l
Externí odkaz:
https://doaj.org/article/3005b2e0a2d6495d964d5dc6d482dff2
Autor:
Kallanthottathil G. Rajeev, Nicole M. Gaudelli, Yusuf S. Nasrullah, Soumyashree A. Gangopadhyay, Andrew M. Bellinger, Sara P. Garcia, James Madsen, Jamie E. DeNizio, Athul Sanjeev, Lisa N. Kasiewicz, Giuseppe Ciaramella, Aaron Beach, Ellen Rohde, Anne Marie Mazzola, Thomas V. Colace, Kui Wang, Sowmya Iyer, Caroline W. Reiss, Padma Malyala, Steven H. Y. Fan, Victoria Clendaniel, Christopher J. Cheng, Jennifer Lavoie, Taiji Mizoguchi, Yuri Matsumoto, Madeleine Shay, Kiran Musunuru, Leslie E. Stolz, Maurine C. Braun, Chaitali Dutta, Ying K. Tam, Joseph Nneji, Ryan Garrity, Alexandra C. Chadwick, Souvik Biswas, Michael Amaonye, John D. Ganey, Mary R. Stahley, Huilan Ren, Huei-Mei Chen, Kathleen Berth, Sekar Kathiresan
Publikováno v:
Nature. 593:429-434
Gene-editing technologies, which include the CRISPR–Cas nucleases1–3 and CRISPR base editors4,5, have the potential to permanently modify disease-causing genes in patients6. The demonstration of durable editing in target organs of nonhuman primat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202cb5c958a9c7ceda5f4b4bf29aa718
https://doi.org/10.1038/s41586-021-03534-y
https://doi.org/10.1038/s41586-021-03534-y
Autor:
Sven Putnis, Brett Fritsch, Danè Dabirrahmani, Joseph Cadman, Thomas Neri, Richard Appleyard, Brian M. Devitt, Samuel Grasso, Aaron Beach, David Parker, Takeshi Oshima, Myles Coolican
Publikováno v:
Journal of ISAKOS. 6:66-73
Given the common occurrence of residual laxity and re-injury post anterior cruciate ligament reconstruction (ACLR), additional anterolateral procedures are increasingly used in combination with an ACLR. Despite the perception that there is a risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96b04e45684dd54aa072dc2c589998c
https://doi.org/10.1136/jisakos-2019-000368
https://doi.org/10.1136/jisakos-2019-000368
Autor:
Thomas Neri, Richard Appleyard, Aaron Beach, Myles Coolican, Takeshi Oshima, Danè Dabirrahmani, Sven Putnis, Samuel Grasso, Joseph Cadman, Brian M. Devitt, David Parker, Brett Fritsch
Publikováno v:
Journal of ISAKOS. 6:74-81
Objective The optimal anterolateral procedure to control anterolateral rotational laxity of the knee is still unknown. The objective was to compare the ability of five anterolateral procedures performed in combination with anterior cruciate ligament
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303c1a385f9d7e9ab24be9d5ccc258e9
https://doi.org/10.1136/jisakos-2019-000360
https://doi.org/10.1136/jisakos-2019-000360
Autor:
David Parker, Aaron Beach
Publikováno v:
Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, Vol 9, Iss C, Pp 19-20 (2017)
Externí odkaz:
https://doaj.org/article/9fad21f94bc5400d83d542ce1d509c80
Autor:
Ellen Rohde, Christopher J. Cheng, Souvik Biswas, Anne Marie Mazzola, Kallanthottathil G. Rajeev, Aaron Beach, Huilan Ren, Lisa N. Kasiewicz, Chaitali Dutta, Padma Malyala, Kiran Musunuru, Sekar Kathiresan, Andrew M. Bellinger, Alexandra C. Chadwick
Standard lipid nanoparticles (LNPs) deliver gene editing cargoes to hepatocytes through receptor-mediated uptake via the low-density lipoprotein receptor (LDLR). Homozygous familial hypercholesterolemia (HoFH) is a morbid genetic disease characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37b45fcbbf0d5ddb47b59a097a02d6ce
https://doi.org/10.1101/2021.11.08.467731
https://doi.org/10.1101/2021.11.08.467731
Publikováno v:
Journal of ISAKOS. 4:285-289
Introduction The tibial footprint of the anterior cruciate ligament (ACL) overlaps with the anterior lateral meniscal root (ALMR), and there is a possibility that an anatomical tibial tunnel reaming might damage the attachment of ALMR. The aim of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdcc3b575ead07ddded06728676ce417
https://doi.org/10.1136/jisakos-2019-000303
https://doi.org/10.1136/jisakos-2019-000303
Publikováno v:
The Knee. 26:1010-1019
Determine whether the tibiofemoral motion and electromyographic activity of the knee differs in patients with a medial pivot implant, compared to those with cruciate-retaining and posterior-stabilised designs, during knee extension after Total Knee A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d50c030a5106062b72e853281f065a
https://doi.org/10.1016/j.knee.2019.07.008
https://doi.org/10.1016/j.knee.2019.07.008
Publikováno v:
Clinics in Sports Medicine. 38:235-246
Multiligament knee injuries remain a challenge for the treating surgeon and little is known about the injury patterns and factors determining clinical and gait outcomes after multiligament knee reconstruction (MLKR). This article aims to identify spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb07a5f8452176785ac12885b167a78e
https://doi.org/10.1016/j.csm.2018.11.010
https://doi.org/10.1016/j.csm.2018.11.010
Publikováno v:
Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, Vol 6, Iss C, p 38 (2016)
Externí odkaz:
https://doaj.org/article/ebfa93a9f9da441ea7f7f775ec0c23ed