Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aarathi Sugathan"'
Autor:
Yijing Zhang, Kathrin Klein, Aarathi Sugathan, Najlla Nassery, Alan Dombkowski, Ulrich M Zanger, David J Waxman
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23506 (2011)
Sex-differences in human liver gene expression were characterized on a genome-wide scale using a large liver sample collection, allowing for detection of small expression differences with high statistical power. 1,249 sex-biased genes were identified
Externí odkaz:
https://doaj.org/article/359e8da2932b42fba0def007546e7558
Autor:
Ian Blumenthal, Bernie Devlin, Joshua Z. Levin, Carl Ernst, Vanessa C. Wheeler, Ashok Ragavendran, Kathryn Roeder, Poornima Manavalan, Aarathi Sugathan, Serkan Erdin, Michael E. Talkowski, Lambertus Klei, James F. Gusella, Jolene R. Guide, Julian Q. Zhou
Publikováno v:
The American Journal of Human Genetics. 94:870-883
Reciprocal copy-number variation (CNV) of a 593 kb region of 16p11.2 is a common genetic cause of autism spectrum disorder (ASD), yet it is not completely penetrant and can manifest in a wide array of phenotypes. To explore its molecular consequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7833441303be8c82a6499f606b8bb3d
https://doi.org/10.1016/j.ajhg.2014.05.004
https://doi.org/10.1016/j.ajhg.2014.05.004
Publikováno v:
Molecular Endocrinology. 23:1242-1254
Phylogenetic footprinting was used to predict functional transcription factor binding sites (TFBS) for signal transducer and activator of transcription (STAT) 5, a GH-activated transcription factor, in the GH-responsive genes IGF-I, SOCS2, and HNF6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b89c29134a430f69b9f2a627fbedd4
https://doi.org/10.1210/me.2008-0449
https://doi.org/10.1210/me.2008-0449
Autor:
Steven D. Sheridan, Stephen J. Haggarty, Marta Biagioli, Serkan Erdin, James F. Gusella, Aarathi Sugathan, Christelle Golzio, Nicholas Katsanis, Michael E. Talkowski, Diane Lucente, Poornima Manavalan, Alexei Stortchevoi, Manolis Kellis, Judith H. Miles, Ian Blumenthal, Ashok Ragavendran, Harrison Brand
Truncating mutations of chromodomain helicase DNA-binding protein 8 (CHD8), and of many other genes with diverse functions, are strong-effect risk factors for autism spectrum disorder (ASD), suggesting multiple mechanisms of pathogenesis. We explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b98fc23caa6b0601577f7411fb6cfea
https://europepmc.org/articles/PMC4210312/
https://europepmc.org/articles/PMC4210312/
Autor:
Aarathi Sugathan, David J. Waxman
Publikováno v:
Molecular and cellular biology. 33(18)
Chromatin state maps were developed to elucidate sex differences in chromatin structure and their impact on sex-differential chromatin accessibility and sex-biased gene expression in mouse liver. Genes in active, inactive, and poised chromatin states
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702c841eaaf155e674f042c72412b523
https://pubmed.ncbi.nlm.nih.gov/23836885
https://pubmed.ncbi.nlm.nih.gov/23836885
Autor:
Alan A. Dombkowski, David J. Waxman, Aarathi Sugathan, Najlla Nassery, Yijing Zhang, Kathrin Klein, Ulrich M. Zanger
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 8, p e23506 (2011)
PLoS ONE, Vol 6, Iss 8, p e23506 (2011)
Sex-differences in human liver gene expression were characterized on a genome-wide scale using a large liver sample collection, allowing for detection of small expression differences with high statistical power. 1,249 sex-biased genes were identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07d26478fed7b42241eaf39a065c340
http://europepmc.org/articles/PMC3155567
http://europepmc.org/articles/PMC3155567
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 95:981-981
Sex differences in liver gene expression are dictated by sex differences in circulating GH profiles. Presently, the pituitary hormone dependence of mouse liver gene expression was investigated on a global scale to discover sex-specific early GH respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553c39c1c1f158f167378e2e543e9f72
https://doi.org/10.1210/jcem.95.2.9993
https://doi.org/10.1210/jcem.95.2.9993