Subcutaneously administered dexmedetomidine is efficiently absorbed and is associated with attenuated cardiovascular effects in healthy volunteers.

Autor: Uusalo P; Department of Anaesthesiology and Intensive Care, University of Turku, P.O. Box 51, (Kiinamyllynkatu 4-8), 20521, Turku, Finland. pijuus@utu.fi.; Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, Turku, Finland. pijuus@utu.fi., Al-Ramahi D; Institute of Biomedicine, University of Turku, and Unit of Clinical Pharmacology, Turku University Hospital, Turku, Finland., Tilli I; Department of Anaesthesiology and Intensive Care, University of Turku, P.O. Box 51, (Kiinamyllynkatu 4-8), 20521, Turku, Finland., Aantaa RA; Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, Turku, Finland., Scheinin M; Institute of Biomedicine, University of Turku, and Unit of Clinical Pharmacology, Turku University Hospital, Turku, Finland., Saari TI; Department of Anaesthesiology and Intensive Care, University of Turku, P.O. Box 51, (Kiinamyllynkatu 4-8), 20521, Turku, Finland.; Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, Turku, Finland.

Publikováno v: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2018 Aug; Vol. 74 (8), pp. 1047-1054. Date of Electronic Publication: 2018 Apr 17.