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of 41
pro vyhledávání: '"Aakash Mahant"'
Autor:
Aakash Mahant Mahant, Fatima Estrada Trejo, Jennifer T. Aguilan, Simone Sidoli, Sallie R. Permar, Betsy C. Herold
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107648- (2023)
Summary: Antibody-dependent cellular cytotoxicity (ADCC) is associated with protection against neonatal herpes. We hypothesized that placental transfer of ADCC-mediating herpes simplex virus (HSV) immunoglobulin G (IgG) is influenced by antigenic tar
Externí odkaz:
https://doaj.org/article/48d8580a2cbb4759a4a1e8fcf61519e0
Autor:
Masayuki Kuraoka, Clare Burn Aschner, Ian W. Windsor, Aakash Mahant Mahant, Scott J. Garforth, Susan Luozheng Kong, Jacqueline M. Achkar, Steven C. Almo, Garnett Kelsoe, Betsy C. Herold
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
There is an unmet need for monoclonal antibodies (mAbs) for prevention or as adjunctive treatment of herpes simplex virus (HSV) disease. Most vaccine and mAb efforts focus on neutralizing antibodies, but for HSV this strategy has proven ineffective.
Externí odkaz:
https://doaj.org/article/4df2398651ce41ada8275773b8c44edc
Publikováno v:
Vaccines, Vol 11, Iss 8, p 1362 (2023)
Herpes simplex viruses (HSV) cause chronic infections with significant morbidity. Prior vaccines, designed to generate neutralizing antibodies (nAbs) targeting glycoprotein D (gD), failed to provide durable protection. We adopted a different strategy
Externí odkaz:
https://doaj.org/article/e2a638bd645d4d09bc9ba285320ba755
Autor:
Aakash Mahant Mahant, Fatima A. Estrada Trejo, Jennifer T Aguilan, Simone Sidoli, Betsy C. Herold
Publikováno v:
Journal of Clinical and Translational Science, Vol 6, Pp 32-33 (2022)
OBJECTIVES/GOALS: Murine and clinical data suggest that antibody-dependent cellular cytotoxicity (ADCC) is associated with greater protection against disseminated neonatal HSV disease. To quantify the relative transfer of Abs with different functions
Externí odkaz:
https://doaj.org/article/084765767aa8492d92f81f4705d2417a
Publikováno v:
Viruses, Vol 13, Iss 7, p 1284 (2021)
Herpes simplex virus (HSV) prevention is a global health priority but, despite decades of research, there is no effective vaccine. Prior efforts focused on generating glycoprotein D (gD) neutralizing antibodies, but clinical trial outcomes were disap
Externí odkaz:
https://doaj.org/article/aab3e2fd1dd04c94a4bd037bd28d057b
Autor:
Aakash Mahant, Narcís Saubi, Yoshiki Eto, Núria Guitart, Josep Ma Gatell, Tomáš Hanke, Joan Joseph
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 8, Pp 1798-1810 (2017)
One of the critical issues that should be addressed in the development of a BCG-based HIV vaccine is genetic plasmid stability. Therefore, to address this issue we have considered using integrative vectors and the auxotrophic mutant of BCG complement
Externí odkaz:
https://doaj.org/article/6f3b9b30d0e64ad89135be2c834ebb54
Autor:
Ferretti, Casara Jean, Cook, Benjamin Lê, Mahant, Aakash Mahant, Chu, Philip, Zhao, Yin, Taylor, Bonnie P., Herold, Betsy C., Hollander, Eric
Publikováno v:
In Neuroscience Applied 2024 3
Autor:
Mahant, Aakash Mahant, Trejo, Fatima Estrada, Aguilan, Jennifer T., Sidoli, Simone, Permar, Sallie R., Herold, Betsy C.
Publikováno v:
In iScience 15 September 2023 26(9)
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Akademický článek
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