Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Aadithya Kannan"'
Autor:
Chloe Hu, José G. Napolitano, Shengli Ma, Frank Hrovat, Mark Ragains, David Russell, Aadithya Kannan, Ian Shieh, Dennis Leung, Ajit S. Narang
Publikováno v:
Journal of Pharmaceutical Sciences. 111:2172-2179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bad238c1b834f0fa3ef641e40021c92
https://doi.org/10.1016/j.xphs.2022.05.019
https://doi.org/10.1016/j.xphs.2022.05.019
Autor:
Aadithya Kannan, Jamie Giddings, Shrenik Mehta, Tiffany Lin, Anthony Tomlinson, Kyle Ritchie, Ian Shieh, Miguel Saggu, Nidhi Doshi
Publikováno v:
Pharmaceutical Research. 39:563-575
Polysorbates (PS) contain polyoxyethylene (POE) sorbitan/isosorbide fatty acid esters that can partially hydrolyze over time in liquid drug products to generate degradants and a remaining intact PS fraction with a modified ester distribution. The deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6321cd3827aa74bb2b52b436d4bca7a
https://doi.org/10.1007/s11095-022-03217-x
https://doi.org/10.1007/s11095-022-03217-x
Autor:
Aadithya Kannan, Michael Chinn, Saeed Izadi, Andrew Maier, James Dvornicky, Mark Fedesco, Eric Day, Asif Ladiwala, Ann Woys
Publikováno v:
Journal of pharmaceutical sciences.
In the manufacturing of therapeutic monoclonal antibodies (mAbs), the final steps of the purification process are typically ultrafiltration/diafiltration (UF/DF), dilution, and conditioning. These steps are developed such that the final drug substanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052fc350c1a955bd6ea3a5d7411b42a0
https://pubmed.ncbi.nlm.nih.gov/36336103
https://pubmed.ncbi.nlm.nih.gov/36336103
Publikováno v:
Molecular Pharmaceutics. 18:1656-1665
Monoclonal antibody (mAb) therapies are rapidly growing for the treatment of various diseases like cancer and autoimmune disorders. Many mAb drug products are sold as prefilled syringes and vials with liquid formulations. Typically, the walls of pref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd87e7e2c96dc1b7b2dadb0415df8ed
https://doi.org/10.1021/acs.molpharmaceut.0c01113
https://doi.org/10.1021/acs.molpharmaceut.0c01113
Publikováno v:
Langmuir. 36:11836-11844
Surfactants in aqueous solutions self-assemble in the presence of salt, to form long, flexible, wormlike micelles (WLM). WLM solutions exhibit viscoelastic properties and are used in many applications, such as for cosmetic products, drag reduction, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2ae92c1ff7fa081a941eef69c91884
https://doi.org/10.1021/acs.langmuir.0c01861
https://doi.org/10.1021/acs.langmuir.0c01861
Publikováno v:
Journal of Colloid and Interface Science. 575:298-305
The dynamics of air bubbles spreading on the underside of solid substrates is an important scientific problem with numerous applications. This work explores the spreading of bubbles against an ultra-thin, porous ultra-high-molecular-weight polyethyle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0faff1cc25f754ac240ceb7e0e93e565
https://doi.org/10.1016/j.jcis.2020.04.086
https://doi.org/10.1016/j.jcis.2020.04.086
Autor:
Aadithya Kannan, Milad Kamkar, Gerald G. Fuller, Parisa Bazazi, Vineeth Chandran Suja, Seyed Hossein Hejazi, Uttandaraman Sundararaj
Publikováno v:
Journal of Colloid and Interface Science. 576:252-263
Hypothesis The properties of oil-in-water emulsions are influenced by the rheology of the aqueous phase (continuous phase) and the rheology of the oil-water interfaces. The bulk and interfacial rheological parameters can be tuned by incorporating nan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b745e9571c7f306d36a8e0d07d28399f
https://doi.org/10.1016/j.jcis.2020.04.105
https://doi.org/10.1016/j.jcis.2020.04.105
Autor:
Satyam Anand, Javier Tajuelo, Zhen Yao, Aadithya Kannan, Gerald G. Fuller, Mariana Rodríguez-Hakim
Publikováno v:
Journal of Rheology. 64:799-816
Asphaltenes are a class of high molecular weight aromatic compounds found in crude oil. They adsorb onto toluene-water interfaces and induce a spontaneous emulsification phenomenon, whereby stable water-in-oil emulsions form without the need of an ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ead961224595492259e2f4719a9a89
https://doi.org/10.1122/1.5145307
https://doi.org/10.1122/1.5145307
Autor:
Catherine M. Meis, Ben S. Ou, Abigail K. Grosskopf, David M. Maahs, Anton A. A. Autzen, Eric A. Appel, Caitlin L. Maikawa, Joseph L. Mann, Aadithya Kannan, Gerald G. Fuller
Publikováno v:
Biomacromolecules
There are 150 million people with diabetes worldwide who require insulin replacement therapy, and the prevalence of diabetes is rising the fastest in middle- and low-income countries. The current formulations require costly refrigerated transport and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baaf93a74e3753b5e20df5e34d36de78
https://pubmed.ncbi.nlm.nih.gov/34213889
https://pubmed.ncbi.nlm.nih.gov/34213889
Publikováno v:
Journal of Colloid and Interface Science. 550:128-138
Monoclonal antibodies (mAbs) are therapeutic proteins used in the treatment of many diseases due to their specificity in binding targets. Aggregation of these molecules is a major challenge in their formulation development. MAbs spontaneously adsorb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141b2c043cd5fdabdd2d793676ea4a6d
https://doi.org/10.1016/j.jcis.2019.04.060
https://doi.org/10.1016/j.jcis.2019.04.060