Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Aadilah Omar"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8600-8610 (2024)
Colorectal cancer (CRC), found in the intestinal tract, is initiated and progresses through various mechanisms, including the dysregulation of signaling pathways. Several signaling pathways, such as EGFR and MAPK, involved in cell proliferation, migr
Externí odkaz:
https://doaj.org/article/62301b02d61b410d9f76d9f7035ffef6
Autor:
Carlo Berrino, Aadilah Omar
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5397-5419 (2024)
The Sonic Hedgehog (Shh) signalling pathway plays a critical role in normal development and tissue homeostasis, guiding cell differentiation, proliferation, and survival. Aberrant activation of this pathway, however, has been implicated in the pathog
Externí odkaz:
https://doaj.org/article/46abf58053ee4560a0b16f66088da405
Publikováno v:
Current Cancer Therapy Reviews. 19:138-155
Background: The Hedgehog (HH) pathway is a key regulator of many important processes in vertebrate embryonic development, including stem cell maintenance, cell differentiation, tissue polarity and cell proliferation. During pathway activation, Ptch n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8686dcbfa200a5b267b067f1148fc67c
https://doi.org/10.2174/1573394718666220822175032
https://doi.org/10.2174/1573394718666220822175032
Autor:
Aadilah Omar, Clement Penny, Paul Ruff, Amber Khan, Kumar Subramanian, Jeyalakshmi Kandhavelu
Publikováno v:
MicroRNA. 8:68-75
Background:Globally, colorectal cancer (CRC) is the third most common cancer in women and the fourth most common cancer in men. Dysregulation of small non-coding miRNAs have been correlated with colon cancer progression. Since there are increasing re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859dbe56d1cc355ebca6c659c584eda1
https://doi.org/10.2174/2211536607666180803100246
https://doi.org/10.2174/2211536607666180803100246
Publikováno v:
Cancer Research. 77:A21-A21
The existence of Cancer Stem Cells (CSCs) has been proven extensively in recent years. CSCs have been positively identified in, and isolated from colon cancer. They have been found to be resilient to therapy and are highly metastatic and it has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9924cd79e3fd4f25148120417961253
https://doi.org/10.1158/1538-7445.newfront17-a21
https://doi.org/10.1158/1538-7445.newfront17-a21
Autor:
Katarina Jovanovic, Dominika Kolodziejczak, Julia Beck, Karen Vana, Chantal Zuber, Bianca Da Costa Dias, Vusi Mbazima, Juergen A. Richt, Aadilah Omar, Bertram Brenig, Stefan Weiss
Publikováno v:
Journal of Molecular Biology. 402:293-300
Enterocytes, a major cell population of the intestinal epithelium, represent one possible barrier to the entry of prions after oral exposure. We established a cell culture system employing enterocytes from different species to study alimentary prion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ce915d709aa0a87610345e1469ba12
https://doi.org/10.1016/j.jmb.2010.06.055
https://doi.org/10.1016/j.jmb.2010.06.055
Publikováno v:
Journal of molecular biology. 419(1-2)
The 37-kDa/67-kDa laminin receptor [laminin receptor precursor/high-affinity laminin receptor (LRP/LR)] is thought to play a major role in invasion and adhesion, key components of metastatic cancer. Lung cancer, cervical cancer, colon cancer and pros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200732f15bf680f98dea16f62f5c36ef
https://pubmed.ncbi.nlm.nih.gov/22391421
https://pubmed.ncbi.nlm.nih.gov/22391421
Autor:
Bianca Da Costa Dias, Stefan Weiss, Kiashanee Moodley, Vusi Mbazima, Robert Caveney, Katarina Jovanovic, Aadilah Omar, Danielle Gonsalves
Publikováno v:
Expert opinion on therapeutic patents. 21(1)
The 37/67 kDa laminin receptor precursor/laminin receptor (LRP/LR) represents a multifunctional protein located on the cell surface, in the cytosol and the nucleus. The receptor acts as a mediator for cell adhesion, cell proliferation and cell differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cd013edaebcada4b1fd308b7e73d5a
https://pubmed.ncbi.nlm.nih.gov/21110766
https://pubmed.ncbi.nlm.nih.gov/21110766
Publikováno v:
Scopus-Elsevier
The 37-kDa/67 kDa laminin receptor (LRP/LR) represents a multifunctional protein. It is a receptor for viruses such as Dengue viruses, Alphaviruses and Adeno-associated viruses (AAV), as well as the cellular prion protein (PrPc) and infectious prions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33536795b86eac2262fcbe5ed03c50c
https://doi.org/10.2741/3667
https://doi.org/10.2741/3667
Autor:
Omar, Aadilah1 (AUTHOR) aadilah.omar@wits.ac.za, Marques, Natasia1 (AUTHOR), Crawford, Nicole1 (AUTHOR)
Publikováno v:
Cancers. Feb2024, Vol. 16 Issue 3, p546. 19p.