Výsledky vyhledávání - "Aadil El Firar"

Supplementary Figure 3 from Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Autor: Marc Laburthe, Thérèse Lehy, Dominique Henin, Pierre Bedossa, Valérie Paradis, Francine Walker, Véronique Descatoire, Christiane Rouyer-Fessard, Magali Fasseu, Aadil El Firar, Thierry Voisin

Supplementary Figure 3 from Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169f27e8e2df7133dce8d4f1a8babfdd
https://doi.org/10.1158/0008-5472.22390047.v1

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Supplementary Figure 1 from Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Supplementary Figure 1 from Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc94ca9d2abd1677854ae7624ac4200
https://doi.org/10.1158/0008-5472.22390053.v1

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Supplementary Figure 4 from Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Supplementary Figure 4 from Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d708e59d07c9559a9c9f2455d7bcac8
https://doi.org/10.1158/0008-5472.22390044.v1

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Supplementary Figure 2 from Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Supplementary Figure 2 from Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d10c6f3b34b56a92194ad817cbfe5f
https://doi.org/10.1158/0008-5472.22390050

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Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Autor: Aadil El Firar, Marc Laburthe, Véronique Descatoire, Pierre Bedossa, Thérèse Lehy, Thierry Voisin, Dominique Hénin, Christiane Rouyer-Fessard, Magali Fasseu, Francine Walker, Valérie Paradis

Publikováno v: Cancer Research. 71:3341-3351

Resistance to apoptosis is a recurrent theme in colon cancer. We have shown previously that the 7-transmembrane spanning receptor OX1R for orexins promotes robust apoptosis in the human colon cancer cell line HT29 through an entirely novel mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccf2457f116974e2d979d81ce2dfd4f
https://doi.org/10.1158/0008-5472.can-10-3473

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Orexins Control Intestinal Glucose Transport by Distinct Neuronal, Endocrine, and Direct Epithelial Pathways

Autor: Robert Ducroc, Marc Laburthe, Thierry Voisin, Aadil El Firar

Publikováno v: Diabetes. 56:2494-2500

OBJECTIVE—Orexins are neuropeptides involved in energy homeostasis. We investigated the effect of orexin A (OxA) and orexin B (OxB) on intestinal glucose transport in the rat. RESEARCH DESIGN AND METHODS AND RESULTS—Injection of orexins led to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea3fa932da82307143f01edddf46d2c
https://doi.org/10.2337/db07-0614

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Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis

Autor: Christiane Rouyer-Fessard, Marc Laburthe, Thierry Voisin, Aadil El Firar, Mariano A. Ostuni, Alain Couvineau

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 23(12)

The orexin neuropeptides promote robust apoptosis in cancer cells. We have recently shown that the 7-transmembrane-spanning orexin receptor OX1R mediates apoptosis through an original mechanism. OX1R is equipped with a tyrosine-based inhibitory motif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95681f963d304d453b664499331c3caa
https://pubmed.ncbi.nlm.nih.gov/19661287

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Orexin-induced apoptosis: the key role of the seven-transmembrane domain orexin type 2 receptor

Autor: Virgile Avondo, Marc Laburthe, Thierry Voisin, Aadil El Firar

Publikováno v: Endocrinology. 147(10)

Orexin-A and orexin-B are regulatory peptides involved in the control of feeding, sleep-wakefulness, and exerting various endocrine and metabolic actions. Recently we demonstrated that orexins, acting at OX(1) receptor (OX(1)R), are proapoptotic pept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26abdc76b364b2498cce8a439d6ae666
https://pubmed.ncbi.nlm.nih.gov/16857748

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