[Marburg virus: the first determined nucleotide sequence of two genes]

Autor: Aa, Bukreev, Aa, Kolykhalov, Viktor Volchkov, Vm, Blinov, Sv, Netesov, Ls, Sandakhchiev

Publikováno v: Europe PubMed Central

The preparations of purified Marburg virus were isolated from blood plasma of infected guinea pigs and characterized. Viral RNA was extracted from the virions. The cDNA was synthesized on the isolated RNA matrix by the reverse transcriptase with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cee798ab5ae36003b03152ff1059d4c3
https://pubmed.ncbi.nlm.nih.gov/1857371

[Study of the structural-functional organization of the natural variola virus genome. I. Cloning HindIII- and XhoI-fragments of viral DNA and sequencing HindIII -M, -L, -I fragments]

Autor: Sn, Shchelkunov, Vm, Blinov, Alexei Totmenin, Ss, Marennikova, Aa, Kolykhalov, Iv, Frolov, Ve, Chizhikov, Vv, Gutorov, Pv, Gashnikov, Ef, Belanov

Publikováno v: Europe PubMed Central

HindIII and XhoI genome fragments of variola major virus strain India-1967 were inserted into the bacterial plasmids and cosmid. Sequencing and computer analysis of the region of HindIII M, L, and I DNA fragments of the virus studied have been carrie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::68195cb7152cf0ba52f87a3eb8bb3493
http://europepmc.org/abstract/med/1335120

Delayed low-dose oral administration of 4'-fluorouridine inhibits pathogenic arenaviruses in animal models of lethal disease.

Autor: Welch SR; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Spengler JR; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Westover JB; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84322, USA., Bailey KW; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84322, USA., Davies KA; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.; Zoonotic and Emerging Disease Research Unit, National Bio and Agro-Defense Facility, US Department of Agriculture, Manhattan, KS 66506, USA., Aida-Ficken V; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Bluemling GR; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Boardman KM; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84322, USA., Wasson SR; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84322, USA., Mao S; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Kuiper DL; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Hager MW; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Saindane MT; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Andrews MK; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Krueger RE; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Sticher ZM; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Jung KH; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84322, USA., Chatterjee P; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Shrivastava-Ranjan P; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Lo MK; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Coleman-McCray JD; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Sorvillo TE; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Genzer SC; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Scholte FEM; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Kelly JA; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Jenks MH; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., McMullan LK; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Albariño CG; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Montgomery JM; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Painter GR; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Natchus MG; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Kolykhalov AA; Emory Institute for Drug Development (EIDD), Emory University, Atlanta, GA 30322, USA., Gowen BB; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84322, USA., Spiropoulou CF; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Flint M; Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 Nov 20; Vol. 16 (774), pp. eado7034. Date of Electronic Publication: 2024 Nov 20.

4'-Fluorouridine inhibits alphavirus replication and infection in vitro and in vivo .

Autor: Yin P; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA., May NA; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA., Lello LS; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Fayed A; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA., Parks MG; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA., Drobish AM; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA., Wang S; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Andrews M; Emory Institute for Drug Development (EIDD), Atlanta, Georgia, USA., Sticher Z; Emory Institute for Drug Development (EIDD), Atlanta, Georgia, USA., Kolykhalov AA; Emory Institute for Drug Development (EIDD), Atlanta, Georgia, USA., Natchus MG; Emory Institute for Drug Development (EIDD), Atlanta, Georgia, USA., Painter GR; Emory Institute for Drug Development (EIDD), Atlanta, Georgia, USA.; Drug Innovations Ventures at Emory (DRIVE), Atlanta, Georgia, USA.; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia, USA., Merits A; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Kielian M; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA., Morrison TE; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.

Publikováno v: MBio [mBio] 2024 Jun 12; Vol. 15 (6), pp. e0042024. Date of Electronic Publication: 2024 May 03.

Modeling Heartland virus disease in mice and therapeutic intervention with 4'-fluorouridine.

Autor: Westover JB; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, USA.; Institute for Antiviral Research, Utah State University, Logan, Utah, USA., Jung KH; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, USA.; Institute for Antiviral Research, Utah State University, Logan, Utah, USA., Alkan C; Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, USA., Boardman KM; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, USA.; Institute for Antiviral Research, Utah State University, Logan, Utah, USA., Van Wettere AJ; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, USA.; Utah Veterinary Diagnostic Laboratory, Logan, Utah, USA., Martens C; Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Rojas I; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, USA.; Institute for Antiviral Research, Utah State University, Logan, Utah, USA., Hicks P; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Thomas AJ; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, USA.; Center for Integrated BioSystems, Utah State University, Logan, Utah, USA., Saindane MT; Emory Institute for Drug Development, Emory University, Atlanta, Georgia, USA., Bluemling GR; Emory Institute for Drug Development, Emory University, Atlanta, Georgia, USA., Mao S; Emory Institute for Drug Development, Emory University, Atlanta, Georgia, USA., Kolykhalov AA; Emory Institute for Drug Development, Emory University, Atlanta, Georgia, USA.; Drug Innovation Ventures at Emory (DRIVE), Atlanta, Georgia, USA., Natchus MG; Emory Institute for Drug Development, Emory University, Atlanta, Georgia, USA., Bates P; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Painter GR; Emory Institute for Drug Development, Emory University, Atlanta, Georgia, USA.; Drug Innovation Ventures at Emory (DRIVE), Atlanta, Georgia, USA.; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, USA., Ikegami T; Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, USA.; The Sealy Institute for Vaccine Sciences, The University of Texas Medical Branch, Galveston, Texas, USA.; The Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas, USA., Gowen BB; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, USA.; Institute for Antiviral Research, Utah State University, Logan, Utah, USA.

Publikováno v: Journal of virology [J Virol] 2024 Apr 16; Vol. 98 (4), pp. e0013224. Date of Electronic Publication: 2024 Mar 21.