Eradication of large human B cell tumors in nude mice with unconjugated CD20 monoclonal antibodies and interleukin 2

Autor: Erik Hooijberg, Jj, Sein, Pc, Den Berk, Aa, Hart, Ma, Valk, Wm, Kast, Cj, Melief, Hekman A

Publikováno v: Europe PubMed Central

Since antibody-dependent cellular cytotoxicity is considered an important mechanism by which mAbs may exert their antitumor effects, it seems likely that these antitumor effects can be enhanced by the activation of the appropriate effector cell popul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dea78bebb8bc45e70d4805b651005c6c
https://pubmed.ncbi.nlm.nih.gov/7540106

Kras-2 alleles, mutations, and lung tumor susceptibility in the mouse--an evaluation

Autor: Remond Fijneman, Ra, Ophoff, Aa, Hart, Demant P

Publikováno v: Europe PubMed Central

Lung Tumor Susceptibility (LTS) in the mouse has been shown to be influenced by loci within the Major Histocompatibility Complex (MHC) and the Kras-2 regions. In crosses between susceptible and resistant strains, one allele of Kras-2 has been linked

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::58c743b1ba3d802d25fc40bd8093768f
http://europepmc.org/abstract/med/8152802

Patterns of Care and Outcomes of Rectal Cancer Patients from the Iowa Cancer Registry: Role of Hospital Volume and Tumor Location.

Autor: Goffredo P; Division of Colon & Rectal Surgery, University of Minnesota, Minneapolis, MN, USA., Hart AA; Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Tran CG; Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Kahl AR; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA.; Iowa Cancer Registry, University of Iowa College of Public Health, Iowa City, IA, USA., Gao X; Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Del Vecchio NJ; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Charlton ME; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA.; Iowa Cancer Registry, University of Iowa College of Public Health, Iowa City, IA, USA., Hassan I; Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Imran-hassan@uiowa.edu.

Publikováno v: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract [J Gastrointest Surg] 2023 Jun; Vol. 27 (6), pp. 1228-1237. Date of Electronic Publication: 2023 Mar 22.

A Genotype-Phenotype Analysis of Glutathione Peroxidase 4 in Human Atrial Myocardium and Its Association with Postoperative Atrial Fibrillation.

Autor: Berdaweel IA; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA., Hart AA; Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA., Jatis AJ; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA., Karlan N; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA., Akhter SA; Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina Heart Institute, Greenville, NC 28592, USA., Gaine ME; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA., Smith RM; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA., Anderson EJ; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA 52242, USA.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2022 Apr 06; Vol. 11 (4). Date of Electronic Publication: 2022 Apr 06.

Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen-Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design.

Autor: Eron SJ; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Huang H; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Agafonov RV; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Fitzgerald ME; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Patel J; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Michael RE; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Lee TD; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Hart AA; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Shaulsky J; Dassault Systèmes BIOVIA, 5005 Wateridge Vista Dr, San Diego, California 92121, United States., Nasveschuk CG; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Phillips AJ; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Fisher SL; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States., Good A; C4 Therapeutics, Inc., 490 Arsenal Way Suite 200, Watertown, Massachusetts 02472, United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2021 Nov 19; Vol. 16 (11), pp. 2228-2243. Date of Electronic Publication: 2021 Sep 28.