Synergistic Potential of Zidovudine Drug Encapsulating in g-C3N4 Nanosheet: A Quantum Mechanical Investigation for Enhanced HIV/AIDS Therapy.

Autor: Ashiq, Mehreen, Zahid, Muhammad Nauman, Malik, Yumna, Alghamdi, Abeer Ahmed, Abdelmohsen, Shaimaa A. M., Iqbal, Javed

Publikováno v: BioNanoScience; Dec2024, Vol. 14 Issue 5, p5436-5457, 22p

Probing the Molecular Mechanisms of AZT Drug Resistance Mediated by HIV-1 Reverse Transcriptase Using a Transient Kinetic Analysis

Autor: Joseph A. Vaccaro, Eisuke Murakami, Aravind Basavapathruni, Dagny Ulrich, Karen S. Anderson, Chung K. Chu, Adrian S. Ray, Raymond F. Schinazi

Publikováno v: Biochemistry. 42:8831-8841

Several hypotheses have been proposed to explain the development of resistance to the anti-HIV drug AZT. Clinical findings show that AZT resistance mutations in HIV-1 reverse transcriptase (RT) not only reduce susceptibility to thymidine analogues bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc3c0203626b2941226efae552a854e
https://doi.org/10.1021/bi034435l

AZT Drug Resistance Conferred by a Dipeptide Insertion in the Fingers of HIV-1 Reverse Transcriptase Involves Multiple Mechanisms

Autor: Li, An, Johnson, Kenneth A.

Publikováno v: In Biophysical Journal 29 January 2013 104(2) Supplement 1:76a-76a

Aplicación de métodos numéricos utilizando MATLAB al modelado del fármaco AZT y la supervivencia con SIDA

Autor: Rodríguez González, Ihosvany, Bermudez Peña, Anié

Publikováno v: Innovation and Software; Vol 1 No 1 (2020): March-August; 26-38
Innovación y Software; Vol. 1 Núm. 1 (2020): Marzo-Agosto; 26-38
Revistas-Universidad La Salle
Universidad La Salle
instacron:USALLE

In our work we conducted a study for solving differential equations an application to modeling in a particular case of the biopharmaceutical sector, which was necessary at the time realize the importance of the application of this drug in a disease t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::75db96ae31b47516875605258d7e791c
https://n2t.net/ark:/42411/s1/a12

Desenvolvimento de dispersões sólidas e nanopartículas poliméricas mucoadesivas de Zidovudina e avaliação da interação biológica com a mucosa intestinal

Autor: Pedreiro, Liliane Neves [UNESP]

Publikováno v: AlephRepositório Institucional da UNESPUniversidade Estadual PaulistaUNESP.

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Externí odkaz: http://hdl.handle.net/11449/132166