Zobrazeno 1 - 10
of 217
pro vyhledávání: '"AZD8055"'
Autor:
Hong Tang, Dilinuer Dilimulati, Zhentao Yang, Ke Zhou, Xiaona Chen, Ruiqi Sun, Ning Wang, Zhi Liang, Suchen Bian, Jialing Zhao, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105099- (2024)
Summary: Background: Hepatocellular carcinoma (HCC) is a highly prevalent and deadly type of cancer, and although pharmacotherapy remains the cornerstone of treatment, therapeutic outcomes are often unsatisfactory. Pharmacological inhibition of mamma
Externí odkaz:
https://doaj.org/article/4d7a06d987e2400bbd6e7f805b9cd9c9
Akademický článek
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Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e14272- (2023)
The increased activity of the mTOR pathway in bladder cancer has been extensively studied, but no satisfactory mTOR inhibitor has been found in bladder cancer. The role of AZD8055, a second-generation mTOR inhibitor, has not been reported in bladder
Externí odkaz:
https://doaj.org/article/9955453bcc1c4e88aef7c83c5b464363
Autor:
Ping Wang, Natalie M. Clark, Trevor M. Nolan, Gaoyuan Song, Olivia G. Whitham, Ching-Yi Liao, Christian Montes-Serey, Diane C. Bassham, Justin W. Walley, Yanhai Yin, Hongqing Guo
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
FERONIA (FER) receptor kinase plays versatile roles in plant growth and development, biotic and abiotic stress responses, and reproduction. Autophagy is a conserved cellular recycling process that is critical for balancing plant growth and stress res
Externí odkaz:
https://doaj.org/article/fb004857ef154aef94e597176407fced
Publikováno v:
New Phytologist, 2019 Jan 01. 221(1), 247-260.
Externí odkaz:
https://www.jstor.org/stable/90026788
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11309 (2022)
Auxenochlorella pyrenoidosa is an efficient photosynthetic microalga with autotrophic growth and reproduction, which has the advantages of rich nutrition and high protein content. Target of rapamycin (TOR) is a conserved protein kinase in eukaryotes
Externí odkaz:
https://doaj.org/article/5276ddb3d9494b849d948b6796727867
Autor:
Eric C. Kauffman, Martin Lang, Soroush Rais-Bahrami, Gopal N. Gupta, Darmood Wei, Youfeng Yang, Carole Sourbier, Ramaprasad Srinivasan
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Renal cell carcinomas (RCC) harboring a TFE3 gene fusion (TfRCC) represent an aggressive subset of kidney tumors. Key signaling pathways of TfRCC are unknown and preclinical in vivo data are lacking. We investigated Akt/mTOR pathw
Externí odkaz:
https://doaj.org/article/696cb64c4fe04f6c9333b63f75d6702e
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7451 (2022)
Target of rapamycin (TOR) is a serine/threonine protein kinase that plays a central regulating role in cell proliferation, growth, and metabolism, but little is known about the TOR signaling pathway in Chlorella sorokiniana. In this study, a Chlorell
Externí odkaz:
https://doaj.org/article/182475559c7d43ea9716b9aec65d7c92
Publikováno v:
Frontiers in Plant Science, Vol 11 (2021)
ABSCISIC ACID INSENSITIVE5 (ABI5) is an important regulator of abscisic acid (ABA) signaling pathway involved in regulating seed germination and postgerminative growth in Arabidopsis, which integrates various phytohormone pathways to balance plant gr
Externí odkaz:
https://doaj.org/article/4001ca4d905a46ab8b1113f30873cdec