In silico exploration of phytocompounds from AYUSH-64 medicinal plants against SARS CoV-2 RNA-dependent RNA polymerase

Autor: Cheemanapalli, Srinivasulu ^{a, 1}, Golla, Ramanjaneyulu ^{b, 1, ⁎}, Pagidi, Sudhakar ^c, Pantangi, Seshapani ^d

Publikováno v: In Journal of Ayurveda and Integrative Medicine November-December 2024 15(6)

Disease Characteristics, Care-Seeking Behavior, and Outcomes Associated With the Use of AYUSH-64 in COVID-19 Patients in Home Isolation in India: A Community-Based Cross-Sectional Analysis

Autor: Narayanam Srikanth, Adarsh Kumar, Bhogavalli Chandrasekhararao, Richa Singhal, Babita Yadav, Shruti Khanduri, Sophia Jameela, Amit Kumar Rai, Arunabh Tripathi, Rakesh Rana, Azeem Ahmad, Bhagwan Sahai Sharma, Ankit Jaiswal, Rajesh Kotecha, State Level Collaborators, Tanuja Nesari, Mahesh Vyas, Umesh Tagade, Anup Thakar, Nilesh Bhatt, Kalpesh Dattani, Sagar Bhinde, Sanjeev Sharma, Pawan Kumar Godatwar, Nisha Ojha, H.M.L. Meena, Harish Bhakuni, Pradeep Kumar Goswami, Bishnu Choudhury, K Nishanth, AJV Sai Prasad, Sujata Dhoke, K Midhuna Mohan, Savita Gopod, Arvind Kumar, Ekta Dogra, G.K. Bora, K S Pravin, Pravin Masarom Radheshyam, P.L. Bharati, Jeuti Rani Das, Vimal Tewari, Deepika Tewari, Ritika Mishra, Kuldeep, D.S. Rotwar, Anil Ahvad, Sumed Paikrao, Amit Madan, Nandini Jadhav, Vikas Nariyal, Kavita Vyas, Anubha Chandla, Vineeta Negi, Chris Antony, Vipin Sharma, Poonam Mohod, Subhash Sharma, Meenakshi Suri, Aaditya Shah, G.V. Ramana, C Tejaswini, Raghavendra, S.K. Giri, Shashidhar Doddamani, M.N Shubhashree, Srinibash Sahoo, K.M. Pratap Shankar, Parvathy.G. Nair, Devi R Nair, V. Krishna Kumar, P.P. Pradeep Kumar, E Remya, A P Karthika, T.P Sinimol, P P Meghna, Praveen Balakrishnan, Emy.S. Surendran, Varsha Sumedhan, Amit Kumar, S.B. Singh, Neelam Singh, Anil Mangal, Deepa Sharma, Laxman Bhurke, Dattatray Dighe, Kuldeep Choudhary, Saylee Deshmukh, Sneha Marlewar, Shyam Kale, U.R. Shekhar Namboori, Savita Sharma, Priya Thakre, Prashant Shinde, Balaji Potbare, Deepak Rahangdale, Gwachung Magh, G.C. Bhuyan, P. Panda, K.K. Ratha, Krishna Rao, S Indu, A.K. Panda, Banamali Das, Susmita Ota, Rinku Tomar, Harbans Singh, Sandeep Baheti, Sanjeev Kumar, S Mahesh, Sangeeta Sangvikar, S.K. Vedi, Swati Sharma, V.B. Kumawat, Suhash Choudhary, Monika Kumari, P P Indu, Rahul D. Ghuse, Shriprakash, Shrawan Kumar Sahu, Ashok Kumar Sinha, P. Srinivas, K. Prameela Devi, S Asha, Sojeetra Niral, Karisma Singh, Kamble Pallavi, Ravi Ranjan Singh, Anjali B Prasad, Mayur Surana, Sanjay Kumar Singh, Harit Kumari, A.K. Srivastava, Tarun Kumar, Deepshikha Arya, D.S. Sahu, Tushar Kanti Mondal, L.D. Barik, Suparna Saha, Ranjita Ekka, Shakti Bhushan, Achintya Mitra, Saroj Kumar Debnath, Debajyoti Das, M Akashlal, A Abhayadev, Hemant Gupta, Ajay P Yadav, Asim Ali Khan, Munawar H Kazmi, Minhaj, Rahat Raza, Md.Nafees Khan, Md. Ishtiyaq Alam, Haseeb Alam Lari, N. Zaheer Ahmed, Hakimuddin Khan, Younis Iftikhar, Seema Akbar, Sheeren Afza, Mohammad Fazil, Ashok Kumar, Mohd Tarique, Amir Faisal Khan, Aijaz Ahmed, Anil Khurana, S. Karunakara Moorthi, Subhash Kaushik, Nitin Kumar Saklani, B. S. Rawat, Brunda Bezawada, Sunil Ramteke, A.K. Prusty, Liyi Karso, Amit Srivastav, Ratan Chandra Shil, Partha Pratim Pal, Lipipushpa Debata, G. Ravi Chandra Reddy, Sunil Prasad, Uttam Singh, Baidurjya Bhattacharjee, Santosh Kumar Tamang, Ravi kumar Sadarla, Pawan Sharma, Amulya Ratna Sahoo, Vibha, P Prasad, D. Karthikeyan, Raghvendra Rao, Surender Sandhu, Mohan Rao, HS Vadiraj, Ishwar V. Basavaraddi, Ishwar N Achary, K Satyalakshmi, Shivkesh, P. Yuvaraj Paul, Subhas Singh, Austin Jose, Robindra Teron, Imlikumba, Addul Wadud, Abdul Nasir Ansari, Tariq Nadeem Khan, Abdul Moheen, Tsewang Dolma, Tenzin Tenba, Anupam Srivastav, N. Ramakrishnan, Surendra Soni, Ram Shukla, Rohini Salve, M.N. Shaikh, Daxen Trivedi, Shital Bhagiya, Asha Patel, Anup Indoriya, Rachna Gandhi, Naresh Jain, Nirmal Chavada, Rahul Shingadiya, Nilesh Bhadraka, Nrupesh Gupta, Dilip Italiya, Piyush Shah, Maya Chaudhari, Sumit Patel, Bhavin Chaudhari, Mehul Parmar

Publikováno v: Frontiers in Public Health, Vol 10 (2022)

BackgroundDuring the second wave of the COVID-19 pandemic in India, the Ministry of Ayush conducted a community study to provide therapeutic care to patients with asymptomatic, mild, and moderate COVID-19 in home isolation based on the empirical evid

Externí odkaz: https://doaj.org/article/ae64239b77ac4a5f845b2816a95b8d66

In silico evaluation of the compounds of the ayurvedic drug, AYUSH-64, for the action against the SARS-CoV-2 main protease

Autor: Thrigulla Saketh Ram, Manne Munikumar, Vankudavath Naik Raju, Parasannanavar Devaraj, Naveen Kumar Boiroju, Rajkumar Hemalatha, P.V.V. Prasad, Manohar Gundeti, Brijesh S. Sisodia, Sharad Pawar, G.P. Prasad, Mukesh Chincholikar, Sumeet Goel, Anupam Mangal, Sudesh Gaidhani, N. Srikanth, K.S. Dhiman

Publikováno v: Journal of Ayurveda and Integrative Medicine, Vol 13, Iss 1, Pp 100413- (2022)

Background: Outbreak of Corona Virus Disease in late 2019 (COVID-19) has become a pandemic global Public health emergency. Since there is no approved anti-viral drug or vaccine declared for the disease and investigating existing drugs against the COV

Externí odkaz: https://doaj.org/article/7cc59cfad0a94eb9b1ac39d17d74c02e

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In vitro effect of Withania somnifera, AYUSH-64, and remdesivir on the activity of CYP-450 enzymes: Implications for possible herb−drug interactions in the management of COVID-19

Autor: Siva Swapna Kasarla, Swapnil P. Borse, Yashwant Kumar, Neha Sharma, Madhu Dikshit

Publikováno v: Frontiers in Pharmacology. 13

Ayurvedic medicines Withania somnifera Dunal (ashwagandha) and AYUSH-64 have been used for the prevention and management of COVID-19 in India. The present study explores the effect of Ashwagandha and AYUSH-64 on important human CYP enzymes (CYP3A4, C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b6cd7c8428eae577ab07cb3f5b8d48