Zobrazeno 1 - 10 of 317 pro vyhledávání: '"AW Harris"'
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Effect of Local Inhibition of Nitric Oxide Synthesis on Forearm Blood Flow and Dorsal Hand Vein Size in Patients with Alcoholic Cirrhosis
Autor: P. Vallance, J. D. Maxwell, AW Harris, Alison Calver
Publikováno v: Clinical Science. 86:203-208
1. Nitric oxide (NO) is a potent endogenous vasodilator and plays a role in the control of resting vascular tone. Patients with cirrhosis have a hyperdynamic circulation with reduced blood pressure and decreased peripheral resistance, and it is possi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96bea0695eeca0ce2e22c57ff1f14ebf
https://doi.org/10.1042/cs0860203
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3
PTU-074 Optimising crohn’s disease treatment based on the rutgeerts’ score 12 months after ileo-colic resection improves clinical outcomes at 3 years compared to standard practice
Autor: BS Kailey, PA Blaker, AW Harris, D Rajashekar, L Macken
Publikováno v: Gut. 64:A93.1-A93
Introduction Clinical relapse of Crohn’s Disease (CD) occurs in 20–30% of patients at 1 year following intestinal resection, increasing by 10% per year without treatment. 1 Work by Rutgeerts’ et al . 2 within a tertiary centre supports the prac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb6914da917e086e4a531c6e57ba1c7e
https://doi.org/10.1136/gutjnl-2015-309861.189
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4
PTU-063 A Prospective Audit Of The Use Of Tacrolimus In Patients With Refractory Subacute Ulcerative Colitis In A District General Hospital
Autor: AW Harris, AS Dhillon
Publikováno v: Gut. 63:A66.1-A66
Introduction Tacrolimus appears to be effective short-term treatment for patients with refractory ulcerative colitis (UC) 1 and is recommended by NICE 2 in suitable patients. We report our experience in a district general hospital out-patient setting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0904b2742e772835613ead9deac26320
https://doi.org/10.1136/gutjnl-2014-307263.137
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5
CD95 (Fas/APO-1) and p53 signal apoptosis independently in diverse cell types
Autor: O'Connor L, Aw, Harris, Andreas Strasser
Publikováno v: Europe PubMed Central
The tumor suppressor p53 exerts its antioncogenic effects in cells chiefly by regulating their progression through the cell cycle and by inducing cell death. It has been claimed that p53-transduced apoptosis involves the death receptor CD95 (Fas/APO-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d988701ea9c48a3c29b60c6e40aca4ba
https://pubmed.ncbi.nlm.nih.gov/10728678
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6
Effect of a bcl-2 transgene on production and localization of precursor B cells in mouse bone marrow
Autor: Janani R, Aw, Harris, Andreas Strasser, Dhanoa S, Plyam R, Dg, Osmond
Publikováno v: Europe PubMed Central
Many B cell precursors die while differentiating in mouse bone marrow. To ascertain the mechanisms involved in this process, populations of B lineage cells and their tissue localization were analyzed in bone marrow of transgenic mice overexpressing t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::971e828b52ff6298ae1fe8567846124c
https://pubmed.ncbi.nlm.nih.gov/9728934
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7
Transcriptional regulation of vav, a gene expressed throughout the hematopoietic compartment
Autor: Ogilvy S, Ag, Elefanty, Visvader J, Ml, Bath, Aw, Harris, Jerry Adams
Publikováno v: Europe PubMed Central
The vav gene is expressed in all hematopoietic but few other cell types. To explore its unusual compartment-wide regulation, we cloned the murine gene, sequenced its promoter region, identified DNase I hypersensitive (HS) sites in the chromatin, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::99993abb41fa1636ef5eb1eeef85b0a1
https://pubmed.ncbi.nlm.nih.gov/9427694
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8
Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo
Autor: Reilly La, O., Aw, Harris, David Tarlinton, Lm, Corcoran, Strasser A
Publikováno v: Europe PubMed Central
B lymphocyte differentiation proceeds through a series of alternating stages of proliferative expansion interspersed with noncycling stationary phases during which cells undergo either positive selection or apoptotic cell death. The molecular control
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5a498c77ebc60966bb7778775b31ca2c
https://pubmed.ncbi.nlm.nih.gov/9278319
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9
Perturbed development of T and B cells in mice expressing an Hlx homeobox transgene
Autor: Jd, Allen, Aw, Harris, Ml, Bath, Andreas Strasser, Scollay R, Jm, Adams
Publikováno v: Europe PubMed Central
Within the lymphoid compartment of mice, the Hlx homeobox gene is expressed only at early stages of B-lymphoid differentiation. To determine whether Hlx influences lymphopoiesis, transgenic mice were developed to enforce Hlx expression throughout the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dc35d5897e2eaa7eeeea12e7826e92d3
https://pubmed.ncbi.nlm.nih.gov/7836739
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10
CD4+8- and CD4-8+ mature thymocytes require different post-selection processing for final development
Autor: Ht, Petrie, Andreas Strasser, Aw, Harris, Hugo P, Shortman K
Publikováno v: Europe PubMed Central
Two primary types of TCR-alpha/beta+ T cells are found in the peripheral lymphoid system; CD4+8- T cells, with MHC-class II restricted TCR, and CD4-8+ T cells, which are MHC-class I restricted. Both lineages develop in the thymus from a series of com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c878ac9e5bf2e25634ef1345a4178fe0
https://pubmed.ncbi.nlm.nih.gov/8101540
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