CLINICAL APPLICATION OF PLASMA PROTEIN C DETERMINATION

Autor: RM Bertina, George Zhu, AW Broekmans

Publikováno v: Universal Journal of Pharmaceutical Research.

Objective: Protein C, a vitamin K-dependent coagulation factor, is involved in blood coagulation. Activated protein C inactivates Va and VIIIa and stimulates fibrinolysis. In this process, protein S serve as an important factor for activated protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6265a0faa717a38ad74fc2f724886d81
https://doi.org/10.22270/ujpr.v5i6.509

Development and Regulation of Gene and Cell-Based Therapies in Europe: A Quantification and Reflection.

Autor: Ten Ham RMT; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Hövels AM; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Klungel OH; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Leufkens HGM; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands; Lygature, Utrecht, The Netherlands., Broekmans AW; Lygature, Utrecht, The Netherlands., Hoekman J; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands; Innovation Studies Group, Copernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands. Electronic address: j.hoekman@uu.nl.

Publikováno v: Trends in pharmacological sciences [Trends Pharmacol Sci] 2020 Feb; Vol. 41 (2), pp. 67-71. Date of Electronic Publication: 2020 Jan 13.

The evolution of adaptiveness: balancing speed and evidence.

Autor: Eichler HG; European Medicines Agency (EMA), London, UK., Barker R; Centre for the Advancement of Sustainable Medical Innovation (CASMI), Oxford, UK., Bedlington N; European Patients Forum (EPF), Brussels, Belgium., Bouvy JC; National Institute for Health and Care Excellence (NICE), London, UK., Broekmans AW; Lygature, Utrecht, Netherlands., Bucsics A; Mechanism of Coordinated Access to Orphan Medicinal Products (MoCA), Vienna, Austria., Cerreta F; European Medicines Agency (EMA), London, UK., Corriol-Rohou S; AstraZeneca, Paris, France., Granados A; Sanofi, Barcelona, Catalunya, Spain., Le Cam Y; EURORDIS, Paris, France., Schuurman A; National Health Care Institute (ZIN), Diemen, Netherlands.

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Traceability of Biologics in The Netherlands: An Analysis of Information-Recording Systems in Clinical Practice and Spontaneous ADR Reports.

Autor: Klein K; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands. k.klein@escher-project.org.; TI Pharma Escher, Leiden, The Netherlands. k.klein@escher-project.org.; Exon Consultancy, Amsterdam, The Netherlands. k.klein@escher-project.org., Scholl JH; The Netherlands Pharmacovigilance Centre Lareb, Den Bosch, The Netherlands., Vermeer NS; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.; Medicines Evaluation Board (MEB), Utrecht, The Netherlands., Broekmans AW; TI Pharma Escher, Leiden, The Netherlands., Van Puijenbroek EP; The Netherlands Pharmacovigilance Centre Lareb, Den Bosch, The Netherlands., De Bruin ML; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands. M.L.deBruin@uu.nl.; Medicines Evaluation Board (MEB), Utrecht, The Netherlands. M.L.deBruin@uu.nl., Stolk P; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.; TI Pharma Escher, Leiden, The Netherlands.; Exon Consultancy, Amsterdam, The Netherlands.

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[The new pharmacovigilance legislation in practice].

Autor: Broekmans AW; Vinkel., Mol PG

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