Zobrazeno 1 - 10
of 173
pro vyhledávání: '"AV-1451"'
Autor:
Michael J. Pontecorvo, C. Dirk Keene, Thomas G. Beach, Thomas J. Montine, Anupa K. Arora, Michael D. Devous, Michael Navitsky, Ian Kennedy, Abhinay D. Joshi, Ming Lu, Geidy E. Serrano, Lucia I. Sue, Anthony J. Intorcia, Shannon E. Rose, Angela Wilson, Leanne Hellstern, Natalie Coleman, Matthew Flitter, Patricia Aldea, Adam S. Fleisher, Mark A. Mintun, Andrew Siderowf
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Background The objective of this study was to make a quantitative comparison of flortaucipir PET retention with pathological tau and β-amyloid across a range of brain regions at autopsy. Methods Patients with dementia (two with clinical dia
Externí odkaz:
https://doaj.org/article/c560e3ec351446138c0423bbda783d83
Akademický článek
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Autor:
Christina B. Young, Susan M. Landau, Theresa M. Harrison, Kathleen L. Poston, Elizabeth C. Mormino
Publikováno v:
NeuroImage, Vol 243, Iss , Pp 118553- (2021)
Tau PET has allowed for critical insights into in vivo patterns of tau accumulation and change in individuals early in the Alzheimer's disease (AD) continuum. A key methodological step in tau PET analyses is the selection of a reference region, but t
Externí odkaz:
https://doaj.org/article/a75fe8eccb224803b4829ec4c0a73e8a
Autor:
Christopher G. Schwarz, Terry M. Therneau, Stephen D. Weigand, Jeffrey L. Gunter, Val J. Lowe, Scott A. Przybelski, Matthew L. Senjem, Hugo Botha, Prashanthi Vemuri, Kejal Kantarci, Bradley F. Boeve, Jennifer L. Whitwell, Keith A. Josephs, Ronald C. Petersen, David S. Knopman, Clifford R. Jack, Jr
Publikováno v:
NeuroImage, Vol 238, Iss , Pp 118259- (2021)
Since tau PET tracers were introduced, investigators have quantified them using a wide variety of automated methods. As longitudinal cohort studies acquire second and third time points of serial within-person tau PET data, determining the best pipeli
Externí odkaz:
https://doaj.org/article/876d2dc8070a43d89899380f4fd80a25
Autor:
Jacob Ziontz, Murat Bilgel, Andrea T. Shafer, Abhay Moghekar, Wendy Elkins, Jessica Helphrey, Gabriela Gomez, Danielle June, Michael A. McDonald, Robert F. Dannals, Babak Behnam Azad, Luigi Ferrucci, Dean F. Wong, Susan M. Resnick
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 637-645 (2019)
Abstract Introduction Tau pathology, a hallmark of Alzheimer's disease, is observed in the brains of virtually all individuals over 70 years. Methods Using 18F‐AV‐1451 (18F‐flortaucipir) positron emission tomography, we evaluated tau pathology
Externí odkaz:
https://doaj.org/article/c72b594430654196b0394bb5b1f54f3f
Autor:
Marta Marquié, Cinthya Agüero, Ana C. Amaral, Alberto Villarejo-Galende, Prianca Ramanan, Michael Siao Tick Chong, Nil Sáez-Calveras, Rachel E. Bennett, Eline E. Verwer, Sally Ji Who Kim, Maeva Dhaynaut, Victor E. Alvarez, Keith A. Johnson, Ann C. McKee, Matthew P. Frosch, Teresa Gómez-Isla
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Introduction Chronic traumatic encephalopathy (CTE) is a tauopathy associated to repetitive head trauma. There are no validated in vivo biomarkers of CTE and a definite diagnosis can only be made at autopsy. Recent studies have shown that po
Externí odkaz:
https://doaj.org/article/9039b5f7fb4e47e382c4f828adc7d929
Autor:
Val J. Lowe, Tyler J. Bruinsma, Hoon‐Ki Min, Emily S. Lundt, Ping Fang, Matthew L. Senjem, Bradley F. Boeve, Keith A. Josephs, Mukesh K. Pandey, Melissa E. Murray, Kejal Kantarci, David T. Jones, Christopher G. Schwarz, David S. Knopman, Ronald C. Petersen, Clifford R. Jack Jr.
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 210-216 (2018)
Abstract Introduction Medial temporal lobe (MTL) uptake on tau–positron emission tomography (PET) is seen not only in Alzheimer's disease (AD) dementia but also in the aging population. The relationship of these findings to the development of AD de
Externí odkaz:
https://doaj.org/article/27e59870c74d4a9facc689b5ee9ab949
Autor:
Laetitia Lemoine, Antoine Leuzy, Konstantinos Chiotis, Elena Rodriguez‐Vieitez, Agneta Nordberg
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 232-236 (2018)
Abstract Ligands targeting tau for use with positron emission tomography have rapidly been developed during the past several years, enabling the in vivo study of tau pathology in patients with Alzheimer's disease and related non‐Alzheimer's disease
Externí odkaz:
https://doaj.org/article/fd8069f8708645ec9a73f901730add67
Autor:
Marta Marquié, Eline E. Verwer, Avery C. Meltzer, Sally Ji Who Kim, Cinthya Agüero, Jose Gonzalez, Sara J. Makaretz, Michael Siao Tick Chong, Prianca Ramanan, Ana C. Amaral, Marc D. Normandin, Charles R. Vanderburg, Stephen N. Gomperts, Keith A. Johnson, Matthew P. Frosch, Teresa Gómez-Isla
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-13 (2017)
Abstract [F-18]-AV-1451 is a novel positron emission tomography (PET) tracer with high affinity to neurofibrillary tau pathology in Alzheimer’s disease (AD). PET studies have shown increased tracer retention in patients clinically diagnosed with de
Externí odkaz:
https://doaj.org/article/34773be917864314bff60df6ef23259c
Autor:
Anne Maass, Susan Landau, Suzanne L. Baker, Andy Horng, Samuel N. Lockhart, Renaud La Joie, Gil D. Rabinovici, William J. Jagust
Publikováno v:
NeuroImage, Vol 157, Iss , Pp 448-463 (2017)
The recent development of tau-specific positron emission tomography (PET) tracers enables in vivo quantification of regional tau pathology, one of the key lesions in Alzheimer's disease (AD). Tau PET imaging may become a useful biomarker for clinical
Externí odkaz:
https://doaj.org/article/c8f2f0e4fba14d088d776fe3fa45666f