Zobrazeno 1 - 10
of 59
pro vyhledávání: '"AURKA Gene"'
Publikováno v:
Cancer Medicine, Vol 10, Iss 18, Pp 6428-6441 (2021)
Cancer Medicine
Cancer Medicine
Introduction The AURKA gene encodes a protein kinase involved in cell cycle regulation and plays an oncogenic role in many cancers. The main objective of this study is to analyze AURKA expression in 13 common cancers and its role in prognostic and dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b995e1df0c53e6e95fb80a5e4ba701c
https://doaj.org/article/004c6e11865645a2b85e581732b2e87d
https://doaj.org/article/004c6e11865645a2b85e581732b2e87d
Publikováno v:
Oncotarget
The involvement of non-coding RNAs (ncRNAs) in cellular physiology and disease pathogenesis is becoming increasingly relevant in recent years specifically in cancer research. Breast cancer (BC) has become a health concern and accounts for most of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4da54112eca3d56146a92b934fef7b7
https://doi.org/10.18632/oncotarget.27811
https://doi.org/10.18632/oncotarget.27811
Publikováno v:
International Journal of Current Research and Review. :19-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aeec65d82cc5c08c88b66a460a5fe26
https://doi.org/10.31782/ijcrr.2020.sp107
https://doi.org/10.31782/ijcrr.2020.sp107
Autor:
Nicholas D. Serra, Brian Elgart, William C Lester, Ben Hale, Ann O. Sperry, Christopher B. Geyer, Taylor Johnson, Rong Wang
Publikováno v:
Biol Reprod
Aurora A kinase (AURKA) is an important regulator of cell division and is required for assembly of the mitotic spindle. We recently reported the unusual finding that this mitotic kinase is also found on the sperm flagellum. To determine its requireme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818fc1e8c7a4db1bf4d48b32cfee2aac
https://europepmc.org/articles/PMC8689116/
https://europepmc.org/articles/PMC8689116/
Autor:
Jing He, Wen Fu, Tiesong Zhang, Tongyi Lu, Ao Lin, Jinhong Zhu, Huimin Xia, Guochang Liu, Li Li, Jiabin Liu
Publikováno v:
Journal of Oncology, Vol 2019 (2019)
Journal of Oncology
Journal of Oncology
Wilms tumor is the most common type of renal malignancy in children. Previous studies have demonstrated that single nucleotide polymorphisms (SNPs) in the AURKA gene could predispose to several human malignancies. We recruited 145 cases and 531 cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2054a0012251e59fa02eed28001718
https://doi.org/10.1155/2019/9074908
https://doi.org/10.1155/2019/9074908
Autor:
Hiroyuki Katayama, Alastair M. Thompson, Aysegul A. Sahin, Kazuharu Kai, Tasneem Bawa-Khalfe, Kwong Kwok Wong, Luisa M. Solis, CM Abbott, Ignacio I. Wistuba, W Tian, David H. Hawke, L Qin, Kaori Sasai, Roland Rad, Shiraj Sen, Warapen Treekitkarnmongkol, Jonathan M. Lee, Y Jltsumori
Publikováno v:
Cancer Research. 79:P1-05
The AURKA gene, encoding Aurora kinase-A (Aurora-A), is frequently amplified and overexpressed across multiple cancer types correlating with poor prognosis. Although the AURKA gene is frequently amplified in human cancers, underlying mechanism(s) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::688f8c4579f20c63f7f8c655d2892654
https://doi.org/10.1158/1538-7445.sabcs18-p1-05-05
https://doi.org/10.1158/1538-7445.sabcs18-p1-05-05
Publikováno v:
Modern Technologies in Medicine
The aim of the study was to identify and quantify lymphocytes with asynchronous replication of the AURKA and TP53 genes in cancer patients versus controls and to assess the diagnostic capabilities of this approach. Materials and Methods The study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed6d5ad87c0629138f97ca3d15ebe6e
https://pubmed.ncbi.nlm.nih.gov/34603753
https://pubmed.ncbi.nlm.nih.gov/34603753
Autor:
Yiqi Wu, Minghui Zhang, Jian Zhou, Jinan Gong, Yang Zhang, Weiwei Yang, Tianzhen Wang, Baocong Shan, Yuanyuan Zhu, Guangyou Wang, Xiaoyu Qi, Xiaobo Li, Ran Zhao
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2020 (2020)
BioMed Research International, Vol 2020 (2020)
AURKA, a cell cycle-regulated kinase, is associated with malignant transformation and progression in many cancer types. We analyzed the expression change of AURKA in pan-cancer and its effect on the prognosis of cancer patients using the TCGA dataset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc85fe77b1229107a01476d592b2f44
http://europepmc.org/articles/PMC7439175
http://europepmc.org/articles/PMC7439175
Autor:
Huan Yu, Xinan Sheng, Zhihong Chi, Jun Guo, Yan Kong, Jiayi Yu, Lu Si, Jie Dai, Meng Ma, Junya Yan, Tianxiao Xu, Huan Tang, Chuanliang Cui, Xiaowen Wu, Longwen Xu
Publikováno v:
Journal of Cancer. 9:1267-1276
Background:AURKA kinase is an essential serine/threonine kinase for mitosis and chromosome stability. The aberrant amplification and overexpression of AURKA are commonly observed in various types of cancer, including cutaneous melanoma. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3bd4c73a90f41830d851d41942e97a0
https://doi.org/10.7150/jca.24013
https://doi.org/10.7150/jca.24013
Autor:
Chin-Jung Hsu, Chia-Hsuan Chou, Hsiao-Chi Tsai, Shun-Fa Yang, Bin Wang, Hsiang-Lin Lee, Whei-Ling Chiang, Chih-Hsin Tang, Chen-Ming Su
Publikováno v:
International Journal of Medical Sciences
Hepatocellular carcinoma (HCC) is a liver malignancy and a major cause of cancer mortality worldwide. AURKA (aurora kinase A) is a mitotic serine/threonine kinase that functions as an oncogene and plays a critical role in hepatocarcinogenesis. We rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aaee38fd78ee0249b54d9ed3d24abf3
http://europepmc.org/articles/PMC5765730
http://europepmc.org/articles/PMC5765730