Výsledky vyhledávání - "AUC, Area Under the ROC Curve"

Demographic, clinical, and laboratory characteristics of patients with COVID-19 during the second and third waves of the pandemic in Egypt

Autor: Manar Ahmed Kamal, Ragaey A. Eid, Marwa Abdallah Shaker, Abdelrahman M. Attia, Mahmoud O. Hassan

Publikováno v: Journal of Infection and Public Health, Vol 14, Iss 10, Pp 1358-1366 (2021)
Journal of Infection and Public Health

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel virus that belongs to the coronaviruses and causes coronavirus disease 2019 (COVID-19). In this study, we explored the demographic details, clinical features, and rout

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb0a1f670f8f8d7dc123cb78a2aaea0
https://doi.org/10.1016/j.jiph.2021.08.009

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Detecting differentially expressed circular RNAs from multiple quantification methods using a generalized linear mixed model

Autor: Alessia Buratin, Chiara Romualdi, Stefania Bortoluzzi, Enrico Gaffo

Publikováno v: Computational and structural biotechnology journal. 20

Finding differentially expressed circular RNAs (circRNAs) is instrumental to understanding the molecular basis of phenotypic variation between conditions linked to circRNA-involving mechanisms. To date, several methods have been developed to identify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f9a678fc4e04b66bd4e5ae7a095bac
https://pubmed.ncbi.nlm.nih.gov/35664231

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Mucosal immune response in BNT162b2 COVID-19 vaccine recipients

Autor: Lorenzo Azzi, Daniela Dalla Gasperina, Giovanni Veronesi, Mariam Shallak, Giuseppe Ietto, Domenico Iovino, Andreina Baj, Francesco Gianfagna, Vittorio Maurino, Daniele Focosi, Fabrizio Maggi, Marco Mario Ferrario, Francesco Dentali, Giulio Carcano, Angelo Tagliabue, Lorenzo Stefano Maffioli, Roberto Sergio Accolla, Greta Forlani

Publikováno v: EBioMedicine, Vol 75, Iss, Pp 103788-(2022)
EBioMedicine

Summary: Background: Although the BNT162b2 COVID-19 vaccine is known to induce IgG neutralizing antibodies in serum protecting against COVID-19, it has not been studied in detail whether it could generate specific immunity at mucosal sites, which rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb4adce58d3fba0b1536acd3fc892eb
http://hdl.handle.net/11383/2130084

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circHIPK3 promotes oxaliplatin-resistance in colorectal cancer through autophagy by sponging miR-637

Autor: Xin Zheng, Yanlei Wang, Chen Li, Xin Zhang, Yongmei Yang, Xinfeng Liu, Rui Zhao, Yanli Zhang, Yi Zhang

Publikováno v: EBioMedicine

Background Resistance to oxaliplatin-based chemotherapy is a major cause of recurrence in colorectal cancer (CRC) patients. There is increasing evidence indicating that circHIPK3 is involved in the development and progression of tumours. However, lit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e440f70190bb7817ac2f424440e8afe8
http://europepmc.org/articles/PMC6838436

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Interfaces Between Alpha-helical Integral Membrane Proteins: Characterization, Prediction, and Docking

Autor: Jeffrey L. Mendenhall, Bian Li, Jens Meiler

Publikováno v: Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 699-711 (2019)
Computational and Structural Biotechnology Journal

Protein-protein interaction (PPI) is an essential mechanism by which proteins perform their biological functions. For globular proteins, the molecular characteristics of such interactions have been well analyzed, and many computational tools are avai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3823f076e75032c853f75bb7125650
http://www.sciencedirect.com/science/article/pii/S200103701930039X

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Retraction notice

Publikováno v: The Journal of Allergy and Clinical Immunology

Background Loss-of-function mutations in the skin barrier protein filaggrin (FLG) are a major risk for atopic dermatitis (AD). The pathogenic sequence of disturbances in skin barrier function before or during the early development of AD is not fully

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c704314b8252d0a76bf676ddba848ec
https://pubmed.ncbi.nlm.nih.gov/25618747

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Predictive Nomogram for Severe COVID-19 and Identification of Mortality-Related Immune Features

Autor: Xi Zhou, Huafang Wang, Shidai Mu, Yu Hu, Heng Mei, Lisha Ai, Xiaoyan Zhao, Miao Wang, Wei Chen, Li Cai

Publikováno v: The Journal of Allergy and Clinical Immunology. in Practice
The Journal of Allergy and Clinical Immunology: In Practice

Background Patients with severe 2019 novel coronavirus disease (COVID-19) have a high mortality rate. The early identification of severe COVID-19 is of critical concern. In addition, the correlation between the immunological features and clinical out

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574ee20ba38dbc94ed094e38f392c3bd
http://europepmc.org/articles/PMC7640885

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Decrease in hemoglobin level predicts increased risk for severe respiratory failure in COVID-19 patients with pneumonia

Autor: Takushi Higuchi, Kimitaka Akaike, Hiroshi Takahashi, Kazuhiko Fujii, Takuro Sakagami, Aiko Masunaga, Koichiro Fukuda, Taiyo Komatsu, Hajime Iwagoe, Yuka Tajima, Moriyasu Anai, Yusuke Tomita, Sho Saeki, Daiki Naito, Aoi Miyazaki, Hidenori Ichiyasu, Hiroto Kishi, Takefumi Akasaka

Publikováno v: Respiratory Investigation

Background In December 2019, the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), emerged in Wuhan, China, and has since spread throughout the world. This study aimed to investigate the assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e808f10059eb7cab038ece0ba5db1e
http://europepmc.org/articles/PMC7682330

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Fat fractions from high-resolution 3D radial Dixon MRI for predicting metastatic axillary lymph nodes in breast cancer patients

Autor: Erik Morre Pedersen, Kim Sivesgaard, Thomas Winther Buus, Peer Christiansen, Anders Bonde Jensen, Tanja Linde Fris

Publikováno v: Buus, T W, Sivesgaard, K, Fris, T L, Christiansen, P M, Jensen, A B & Pedersen, E M 2020, ' Fat fractions from high-resolution 3D radial Dixon MRI for predicting metastatic axillary lymph nodes in breast cancer patients ', European journal of radiology open, vol. 7, 100284 . https://doi.org/10.1016/j.ejro.2020.100284
European Journal of Radiology Open, Vol 7, Iss, Pp 100284-(2020)
European Journal of Radiology Open

Highlights • High-Resolution 3D radial Dixon MRI allows for the creation of quantitative fat fraction images. • Lymph node fat fractions improves diagnostic performance of MRI to detect axillary lymph node metastases. • Lymph node fat fractions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8a170d7b907b7eee2f53f020254357
https://pure.au.dk/portal/da/publications/fat-fractions-from-highresolution-3d-radial-dixon-mri-for-predicting-metastatic-axillary-lymph-nodes-in-breast-cancer-patients(a59e89fc-97aa-439d-a770-7c56e4665706).html

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