Zobrazeno 1 - 10
of 20
pro vyhledávání: '"ATTILA MAKÓ"'
Autor:
Attila Makó, Mónika Vastag, Sándor Kolok, Attila Cselenyák, Imre Bata, Bence Farkas, Gábor Szántó
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:3896-3904
Purinergic P2X3 receptors are trimeric ligand-gated ion channels whose antagonism is an appealing yet challenging and not fully validated drug development idea. With the aim of identification of an orally active, potent human P2X3 receptor antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5d790915743231efd881e1e7d2ede4
https://doi.org/10.1016/j.bmcl.2016.07.009
https://doi.org/10.1016/j.bmcl.2016.07.009
Autor:
Éva Bozó, Imre Bata, Ferenc Baska, Réka Mohácsi, Dalma Kurkó, Attila Makó, Katalin Domány-Kovács, Attila Cselenyák, Gábor Szántó, Krisztina Szondiné Kordás
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:127416
Solid preclinical evidence links vasopressin to social behavior in animals, so, extensive work has been initiated to find new vasopressin V1a receptor antagonists which can improve deteriorated social behavior in humans and can treat the core symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b500b74c3418c200ecf2575060519c
https://doi.org/10.1016/j.bmcl.2020.127416
https://doi.org/10.1016/j.bmcl.2020.127416
Autor:
Istvan Vago, Gábor Szántó, Attila Makó, Mónika Vastag, Sándor Kolok, Bence Farkas, Imre Bata, Tamás Hergert
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(16)
Numerous potent P2X3 antagonists have been discovered and the therapeutic potential of P2X3 antagonism already comprises proof-of-concept data obtained in clinical trials with the most advanced compound. We have lately reported the discovery and opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c25dc8b1bfcef41d1e0bfcd2bb8419
https://pubmed.ncbi.nlm.nih.gov/27426300
https://pubmed.ncbi.nlm.nih.gov/27426300
Publikováno v:
Letters in Organic Chemistry. 7:424-431
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7568dbb5229a0378e7b689b0684359d9
https://doi.org/10.2174/157017810791824865
https://doi.org/10.2174/157017810791824865
Autor:
Attila Makó, Áron Szöllősy, Péter Bakó, László Hegedűs, László Drahos, György Keglevich, Zsolt Rapi
Publikováno v:
Tetrahedron: Asymmetry. 21:919-925
The chiral monoaza-15-crown-5 lariat ethers annellated to methyl-4,6-O-benzylidene-α- d -glucopyranoside-1 or mannopyranoside 2 have been applied as phase-transfer catalysts in the epoxidation of substituted chalcones and chalcone analogues with ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69a450f297ed376ba70a3e2bf5d8ff56
https://doi.org/10.1016/j.tetasy.2010.05.009
https://doi.org/10.1016/j.tetasy.2010.05.009
Publikováno v:
Arkivoc. 2009:165-179
The synthesis of novel chiral monoaza-15-crown-5 compounds (1-4) with pyridine-ring starting from methyl-4,6-O-benzylidene-α-D-glucopyranoside and methyl-4,6-O-benzylidene-α-Dmannopyranoside by different methods are reported. These crown ethers sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::411cb1bb4731562a5286333679855372
https://doi.org/10.3998/ark.5550190.0010.716
https://doi.org/10.3998/ark.5550190.0010.716
Publikováno v:
Journal of Molecular Structure. 892:336-342
The synthesis of a novel, optically active crown ether derived from α- d -altropyranoside is described. A significantly different asymmetric induction was generated by the α- d -glucopyranoside-, α- d -mannopyranoside- and α- d -altropyranoside-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a56467240836aee90240daac7657fec3
https://doi.org/10.1016/j.molstruc.2008.05.057
https://doi.org/10.1016/j.molstruc.2008.05.057
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 139:525-535
New chiral monoaza-15-crown-5 compounds anellated to methyl-4,6-O-(1-naphthyl)methylene-α-d-glucopyranoside (2a–2b), to methyl-4,6-O-isopropylidene-α-d-glucopyranoside (3a–3b) and to methyl-α-d-glucopyranoside (4a–4b) have been synthesized.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e28c85591a831b2c83845e7cf61dcd6d
https://doi.org/10.1007/s00706-007-0799-7
https://doi.org/10.1007/s00706-007-0799-7
Publikováno v:
Tetrahedron: Asymmetry. 18:1521-1528
The electronic absorption and CD spectra of (−)- trans -chalcone epoxide and its derivatives with methyl and alkoxy substituents at the ortho -positions of the aromatic rings have been measured. The spectra have been assigned with help of the energ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947433ce37d91108167c7c29a962c5c4
https://doi.org/10.1016/j.tetasy.2007.06.034
https://doi.org/10.1016/j.tetasy.2007.06.034
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 55:295-302
The alkali metal- and ammonium picrate extracting ability of d-glucose- and d-mannose-based 15-crown-5 ethers and related lariat ethers was investigated in dichloromethane – water system. A heteroatom was waried in the crown ether containing a 4,6-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea0b3be97133d2d8c9b2c2db95085de6
https://doi.org/10.1007/s10847-006-9051-z
https://doi.org/10.1007/s10847-006-9051-z