Zobrazeno 1 - 10
of 55
pro vyhledávání: '"ATONAL HOMOLOG"'
Autor:
Jennifer Foulke-Abel, Kelli F. Johnson, Mark Donowitz, Ruxian Lin, Nicholas C. Zachos, Sun Lee, Varsha Singh, Jianyi Yin, Huimin Yu, Yan Rong, Julie In
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 219-232 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims One of the features of ulcerative colitis (UC) is a defect in the protective mucus layer. This has been attributed to a reduced number of goblet cells (GCs). However, it is not known whether abnormal GC mucus secretion also contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9c60b3f44f4ec5b1ede8c2e9a502aa
https://doi.org/10.1016/j.jcmgh.2021.08.010
https://doi.org/10.1016/j.jcmgh.2021.08.010
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Notch signaling coordinates cell differentiation processes in the intestinal epithelium. The transcription factor Nrf2 orchestrates defense mechanisms by regulating cellular redox homeostasis, which, as shown previously in murine li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5ec7721d1b9705691950303dd36e56
https://doi.org/10.1016/j.jcmgh.2020.08.013
https://doi.org/10.1016/j.jcmgh.2020.08.013
Autor:
Min-Shan Chen, Zhaohui Li, Taeko K. Noah, Ying-Wooi Wan, Hari Krishna Yalamanchili, Kristin N. Bell, Eunah Chung, Joo-Seop Park, Maxime M. Mahe, Yuan-Hung Lo, Tiemo J. Klisch, Zhandong Liu, Noah F. Shroyer
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The transcription factor atonal homolog 1 (ATOH1) controls the fate of intestinal progenitors downstream of the Notch signaling pathway. Intestinal progenitors that escape Notch activation express high levels of ATOH1 and commit to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2809660b698d03966ec26e79f4892f33
Autor:
Zengli Liu, Tianli Chen, Rongqi Sun, Yunfei Xu, Bo Qiu, Xiaoming Zhang, Zongli Zhang, Zhipeng Li
Publikováno v:
EBioMedicine
Background: Perihilar cholangiocarcinoma (PHCC) is the most common type of cholangiocarcinoma with the worst prognosis. Radical resection of PHCC is difficult; thus, few effective biomarkers or useful molecular profiles for PHCC have been reported in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155cb7697f054b98040d94d0bc60a157
https://pubmed.ncbi.nlm.nih.gov/31248836
https://pubmed.ncbi.nlm.nih.gov/31248836
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 2, Pp 189-209 (2016)
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 2, Pp 189-209 (2016)
Background & Aims: The embryonic small intestinal epithelium is highly proliferative, and although much is known about mechanisms regulating proliferation in the adult intestine, the mechanisms controlling epithelial cell proliferation in the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82fd5716bbb6773e37720f300cbfbe6
Autor:
Mamoru Watanabe, Ryuichi Okamoto, Yoshinobu Eishi, Tetsuya Nakamura, Nobukatsu Horita, Kiichiro Tsuchiya, Keisuke Kitagaki, Keita Fukushima, Takumi Akashi, Mariko Negi, Eisaku Itoh, Takashi Nagaishi, Yoshihito Kano, Shuji Hibiya, Ryohei Hayashi, Shigeru Oshima
Publikováno v:
Cancer Science
Patients with inflammatory bowel disease (IBD) have an increased risk of developing colitis-associated colorectal cancer (CAC). CAC cells often develop chemoresistance, resulting in a poorer prognosis than that of sporadic colorectal cancer (CRC). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7819b27948a870f5083356951c9865
http://europepmc.org/articles/PMC4556389
http://europepmc.org/articles/PMC4556389
Autor:
Hirosato, Mashima, Noboru, Watanabe, Masanari, Sekine, Satohiro, Matsumoto, Takeharu, Asano, Kazuhito, Yuhashi, Noriyoshi, Sagihara, Shunsuke, Urayoshi, Takeshi, Uehara, Junichi, Fujiwara, Takehiro, Ishii, Rumiko, Tsuboi, Hiroyuki, Miyatani, Hirohide, Ohnishi
Publikováno v:
Biochemistry and Biophysics Reports
Intestinal homeostasis and the coordinated actions of digestion, absorption and excretion are tightly regulated by a number of gastrointestinal hormones. Most of them exert their actions through G-protein-coupled receptors. Recently, we showed that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35e356bf3472af2a120ff894ff223f64
https://pubmed.ncbi.nlm.nih.gov/29387814
https://pubmed.ncbi.nlm.nih.gov/29387814
Autor:
Eamonn Sheridan, Graham R. Taylor, Joanne E. Morgan, Narcis Fernandez-Fuentes, Hussain Jafri, Ahmed Al-Maskari, Özlem Yenice, Colin A. Johnson, Clare V. Logan, Carmel Toomes, Nursel Elcioglu, Manir Ali, Yasmin Raashid, David A. Parry, Martin McKibbin, Chris F. Inglehearn, Kamron N. Khan, Moin Mohamed, Zakia Abdelhamed, James A. Poulter, Ian M. Carr
Publikováno v:
Human Molecular Genetics
The atonal homolog 7 (ATOH7) gene encodes a transcription factor involved in determining the fate of retinal progenitor cells and is particularly required for optic nerve and ganglion cell development. Using a combination of autozygosity mapping and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44839b054654ed20f0fb79dcff1a6cbb
https://doi.org/10.1093/hmg/ddr509
https://doi.org/10.1093/hmg/ddr509
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Akademický článek
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