Zobrazeno 1 - 10
of 856
pro vyhledávání: '"ATOH1"'
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32952- (2024)
Sensorineural hearing loss (SNHL) is a prevalent condition in otolaryngology. A key obstacle is finding effective strategies for regenerating damaged cochlear hair cells in adult animals. A practical and reliable approach has been developed to create
Externí odkaz:
https://doaj.org/article/adbab27e2dd34c4a8afcb0bdee9d2470
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
In the early cerebellar primordium, there are two progenitor zones, the ventricular zone (VZ) residing atop the IVth ventricle and the rhombic lip (RL) at the lateral edges of the developing cerebellum. These zones give rise to the several cell types
Externí odkaz:
https://doaj.org/article/52539f317ad54371922c8965a6f165ab
Autor:
Qing Zhong, Hua‐Gen Wang, Ji‐Hong Yang, Ru‐Hong Tu, An‐Yao Li, Gui‐Rong Zeng, Qiao‐Ling Zheng, Zhi‐ Yu Liu, Zhi‐Xin Shang‐Guan, Xiao‐ Bo Huang, Qiang Huang, Yi‐Fan Li, Hua‐Long Zheng, Guang‐Tan Lin, Ze‐Ning Huang, Kai‐Xiang Xu, Wen‐Wu Qiu, Mei‐Chen Jiang, Ya‐Jun Zhao, Jian‐Xian Lin, Zhi‐Hong Huang, Jing‐Min Huang, Ping Li, Jian‐Wei Xie, Chao‐Hui Zheng, Qi‐Yue Chen, Chang‐Ming Huang
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract Gastric cancer stem cells (GCSCs) are self‐renewing tumor cells that govern chemoresistance in gastric adenocarcinoma (GAC), whereas their regulatory mechanisms remain elusive. Here, the study aims to elucidate the role of ATOH1 in the mai
Externí odkaz:
https://doaj.org/article/d5c450371d7249f382f7578885a3dc87
Autor:
Serena M. Vilasi, Jannett Nguyen, Catherine J. Wang, Lingling Miao, Kenneth Daily, Mary Eid, Joon Seon Song, Hong Jiang, Kris Ylaya, Klaus J. Busam, Maria R. Gaiser, Stephen M. Hewitt, Isaac Brownell
Publikováno v:
Cancers, Vol 16, Iss 4, p 788 (2024)
Merkel cell carcinoma (MCC) and small cell lung cancer (SCLC) can be histologically similar. Immunohistochemistry (IHC) for cytokeratin 20 (CK20) and thyroid transcription factor 1 (TTF-1) are commonly used to differentiate MCC from SCLC; however, th
Externí odkaz:
https://doaj.org/article/41c2cd9c8ce748ab8d24b45c7745c8fc
Autor:
Weiming Mou, Lingxuan Zhu, Tao Yang, Anqi Lin, Qiong Lyu, Linlang Guo, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Colon adenocarcinoma (COAD) is one of the major varieties of malignant tumors threatening human health today. Immune checkpoint inhibitors (ICIs) have recently begun to emerge as an effective option for the treatment of COAD patie
Externí odkaz:
https://doaj.org/article/d96ae038a375463f8fea51c74c36e91d
Autor:
Jipeng Wang, Jianwei Zheng, Haiyan Wang, Haoying He, Shuang Li, Ya Zhang, You Wang, Xiaoxiang Xu, Shuyi Wang
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Sensorineural hearing loss is typically caused by damage to the cochlear hair cells (HCs) due to external stimuli or because of one’s genetic factors and the inability to convert sound mechanical energy into nerve impulses. Adult mammalian cochlear
Externí odkaz:
https://doaj.org/article/7c299d63d5b84a9ca3a960c24d7f88c3
Akademický článek
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Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Although the lineage-determining ability of transcription factors is often modulated according to cellular context, the mechanisms by which such switching occurs are not well known. Using a transcriptional programming model, we found that Atoh1 is re
Externí odkaz:
https://doaj.org/article/2d04b234bab94133a482554eadc0ac79
Autor:
Joshua Po Han Wu, Joanna Yeung, Maryam Rahimi-Balaei, Sih-Rong Wu, Huda Zoghbi, Dan Goldowitz
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The cerebellar nuclear (CN) neurons are a molecularly heterogeneous population whose specification into the different cerebellar nuclei is defined by the expression of varying sets of transcription factors. Here, we present a novel molecular marker,
Externí odkaz:
https://doaj.org/article/b0e9376f5ee24160aa323b4d14d924cb
Akademický článek
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