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pro vyhledávání: '"ATM, ataxia telagectasia mutant"'
Autor:
David J. Adams, Louise van der Weyden
Publikováno v:
Biochimica et Biophysica Acta
Ras proteins play a direct causal role in human cancer with activating mutations in Ras occurring in approximately 30% of tumours. Ras effectors also contribute to cancer, as mutations occur in Ras effectors, notably B-Raf and PI3-K, and drugs blocki