Zobrazeno 1 - 10
of 4 684
pro vyhledávání: '"ATG5"'
Publikováno v:
Neurospine, Vol 21, Iss 3, Pp 925-941 (2024)
Objective The study aimed to investigate the role of N6-methyladenosine (m6A) modification in spinal cord injury (SCI) and its underlying mechanism, focusing on the interplay between m6A methyltransferase-like 3 (METTL3), miR-30c, and autophagy-relat
Externí odkaz:
https://doaj.org/article/2e9b6b00672748dfa8e959dca557f587
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 637-53 (2024)
Intensive care unit-acquired weakness (ICU-AW) is prevalent in critical care, with limited treatment options. Certain microRNAs, like miR-542, are highly expressed in ICU-AW patients. This study investigates the regulatory role and mechanisms of miR-
Externí odkaz:
https://doaj.org/article/66d5bc5a804242149518bda38c6b14d5
Autor:
Hsiao‐Sheng Liu, Yin‐Ping Wang, Pei‐Wen Lin, Man‐Ling Chu, Sheng‐Hui Lan, Shan‐Ying Wu, Ying‐Ray Lee, Hong‐Yi Chang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 7, Pp 631-641 (2024)
Abstract Autophagy is a self‐recycling machinery to maintain cellular homeostasis by degrading harmful materials in the cell. Autophagy‐related gene 5 (Atg5) is required for autophagosome maturation. However, the role of Atg5 in tumorigenesis und
Externí odkaz:
https://doaj.org/article/f842293ee22c4ac499453b39c2812390
Publikováno v:
Tobacco Induced Diseases, Vol 22, Iss April, Pp 1-9 (2024)
Introduction Macrophages play an important role in chronic obstructive pulmonary disease (COPD). Cigarette smoke (CS) impairs autophagy in alveolar macrophages from COPD patients, and autophagic impairment leads to reduced clearance of protein aggreg
Externí odkaz:
https://doaj.org/article/62898d7d3a6a4e9c95d1710777ad1ec5
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Angiotensin (Ang)-(1–7) can reduce airway inflammation and airway remodeling in allergic asthma. Autophagy-related 5 (ATG5) has attracted wide attentions in asthma. However, the effects of Ang-(1–7) on ATG5-mediated autophagy
Externí odkaz:
https://doaj.org/article/0266366ec0054e1ba3adae370e79ca04
Autor:
Inés Ripa, Sabina Andreu, Fernando Josa-Prado, Beatriz Fernández Gómez, Fernando de Castro, María Arribas, Raquel Bello-Morales, José Antonio López-Guerrero
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Herpes Simplex Virus type 1 (HSV-1) 1 is a neurotropic virus that has been associated with neurodegenerative disorders. The dysregulation of autophagy by HSV-1 has been proposed as a potential cause of neurodegeneration. While studies have extensivel
Externí odkaz:
https://doaj.org/article/91b99802dbc049d0872e1e4f2ca445a8
Autor:
Farnaz Seifi, Mojdeh Khajehlandi
Publikováno v:
Jorjani Biomedicine Journal, Vol 11, Iss 4, Pp 19-23 (2023)
Background: The use of complementary medicine in healthcare is increasing rapidly. Therefore, the aim of the current study was to investigate the effect of eight weeks of high-intensity interval training and moderate-intensity continuous training wit
Externí odkaz:
https://doaj.org/article/4c2e082048f24852a197ab1934b0f5f0
Autor:
Parastoo Yousefi, Alireza Tabibzadeh, Abdulhussain Kadhim Jawaziri, Mohsen Mehrjoo, Mandana Akhavan, Leila Allahqoli, Hamid Salehiniya
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 2, Pp n/a-n/a (2024)
Abstract Background Chronic hepatitis B (CHB) virus is the most common risk factor for developing liver malignancy. Autophagy is an essential element in human cell maintenance. Several studies have demonstrated that autophagy plays a vital role in li
Externí odkaz:
https://doaj.org/article/a9a2442a46f34bc1bb3d9237d8817e30
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe molecular mechanisms of hepatic fibrosis (HF), closely related to autophagy, remain unclear. This study aimed to investigate autophagy characteristics in HF.MethodsGene expression profiles (GSE6764, GSE49541 and GSE84044) were downloade
Externí odkaz:
https://doaj.org/article/73b51a414f9649a1bdb21a7ecf44e2fe
Autor:
Bingxin Zheng, Xiangchen Sun, Li Zhang, Guojian Qu, Chongmin Ren, Peng Yan, Chuanli Zhou, Bin Yue
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 57 (2024)
Abstract The cure rates for osteosarcoma have remained unchanged in the past three decades, especially for patients with pulmonary metastasis. Thus, a new and effective treatment for metastatic osteosarcoma is urgently needed. Anlotinib has been repo
Externí odkaz:
https://doaj.org/article/1dc757032990401db2371c149708be37