Zobrazeno 1 - 10
of 2 539
pro vyhledávání: '"ATAC-Seq"'
Autor:
Zhe Zhang, Lebin Chang, Bingjie Wang, Yilin Wei, Xinjian Li, Xiuling Li, Yongqian Zhang, Kejun Wang, Ruimin Qiao, Feng Yang, Tong Yu, Xuelei Han
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Backfat serves as a vital fat reservoir in pigs, and its excessive accumulation will adversely impact pig growth performance, farming efficiency, and pork quality. The aim of this research is to integrate assay for transposase-acc
Externí odkaz:
https://doaj.org/article/62d3c28196894e0589f73492dde66fa5
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2911-2923 (2024)
Inflammatory bowel diseases (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), are complex chronic inflammatory intestinal conditions with a multifaceted pathology, influenced by immune dysregulation and genetic susceptibility. The c
Externí odkaz:
https://doaj.org/article/72cd5ca13d2c48e89dc495b1b916fb89
Autor:
Leonor Schubert Santana, Alejandro Reyes, Sebastian Hoersch, Enrico Ferrero, Christian Kolter, Swann Gaulis, Sebastian Steinhauser
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2190-2199 (2024)
Spatiotemporal regulation of gene expression is controlled by transcription factor (TF) binding to regulatory elements, resulting in a plethora of cell types and cell states from the same genetic information. Due to the importance of regulatory eleme
Externí odkaz:
https://doaj.org/article/b389b0582e8748f19a3f095d7b02a90d
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Broilers stand out as one of the fastest-growing livestock globally, making a substantial contribution to animal meat production. However, the molecular and epigenetic mechanisms underlying the rapid growth and development of broi
Externí odkaz:
https://doaj.org/article/fdd03299e56b4a61b12bab9f667b0cd7
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5291-5306 (2024)
Advancements in single-cell sequencing have transformed the genomics field by allowing researchers to delve into the intricate cellular heterogeneity within tissues at greater resolution. While single-cell omics are more widely applied in model organ
Externí odkaz:
https://doaj.org/article/b19ad2b80f8343f68fb08815f029f1fc
Autor:
Arash Yaghoobi, Seyed Amir Malekpour
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Alzheimer's disease (AD) is a heritable neurodegenerative disease whose long asymptomatic phase makes the early diagnosis of it pivotal. Blood U-p53 has recently emerged as a superior predictive biomarker for AD in the early stage
Externí odkaz:
https://doaj.org/article/6e273edf43e04966a6cc62cf72b3fb88
Autor:
Chen Xu, Yiwei Zhang, Jian Zhou, Jiangnan Zhang, Hui Dong, Xiangmei Chen, Yi Tian, Yuzhang Wu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
RationaleKidney inflammation plays a crucial role in the pathogenesis of IgA nephropathy (IgAN), yet the specific phenotypes of immune cells involved in disease progression remain incompletely understood. Utilizing joint profiling through longitudina
Externí odkaz:
https://doaj.org/article/f4216f365c6f4be6a539a8678c5692ea
Publikováno v:
eLife, Vol 13 (2024)
Assay for Transposase-Accessible Chromatin sequencing (ATAC-Seq) is a widely used technique to explore gene regulatory mechanisms. For most ATAC-Seq data from healthy and diseased tissues such as tumors, chromatin accessibility measurement represents
Externí odkaz:
https://doaj.org/article/9712827c651948438aa338f2d4dd65f8
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Objective: This study was aimed at exploring a specific open region of chromatin in the peripheral blood mononuclear cells (PBMCs) of patients with breast cancer and evaluating its feasibility as a biomarker for diagnosing and predicting breast cance
Externí odkaz:
https://doaj.org/article/93a3b82fbde7460eafc5fd8463637eb7
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Relapse remains a determinant of treatment failure and contributes significantly to mortality in acute myeloid leukemia (AML) patients. Despite efforts to understand AML progression and relapse mechanisms, findings on acquired gene mutations in relap
Externí odkaz:
https://doaj.org/article/10a40f2bfea443fd9af733d3c638f59f