Zobrazeno 1 - 10
of 360
pro vyhledávání: '"ASMs"'
Autor:
Zachary A. Gurard-Levin, Brian McMillan, Douglas A. Whittington, Brian Doyon, Michael D. Scholle, Jacques Ermolieff, Madhavi Bandi, Mu-Sen Liu, Alvaro Amor, William D. Mallender
Publikováno v:
SLAS Technology, Vol 29, Iss 5, Pp 100173- (2024)
Polymerase β (POLB), with dual functionality as a lyase and polymerase, plays a critical role in the base excision repair (BER) pathway to maintain genomic stability. POLB knockout and rescue studies in BRCA1/2-mutant cancer cell lines revealed that
Externí odkaz:
https://doaj.org/article/2814a1a1f9b140339aad8d4a13a4a653
Autor:
Ilaria Sammarra, Maria Eugenia Caligiuri, Maria Celeste Bonacci, Gianfranco Di Gennaro, Francesco Fortunato, Iolanda Martino, Alessia Giugno, Angelo Labate, Antonio Gambardella
Publikováno v:
Epilepsia Open, Vol 9, Iss 3, Pp 1076-1082 (2024)
Abstract Mild mesial temporal lobe epilepsy (MTLE) patients may remain untreated for a considerable time after disease onset or achieve seizure control with a single anti‐seizures medication (ASM). Thus, they represent an optimal population to inve
Externí odkaz:
https://doaj.org/article/9d8c78bd3d3f4c7e8baa1550975e8495
Autor:
Oriano Mecarelli
Publikováno v:
Global & Regional Health Technology Assessment, Vol 11, Iss Suppl. 1 (2024)
Epilepsy is a widespread social disease that affects people of all ages and often involves both diagnostic and therapeutic difficulties. Beyond seizure control, it is necessary to ensure people with epilepsy a good quality of life and respect for hum
Externí odkaz:
https://doaj.org/article/e8a5725fb1ae45c180b65b662832f3d2
Autor:
Michael Magdy Fahmy Girgis, Gergely Farkasinszky, Klára Fekete, István Fekete, Miklós Vecsernyés, Ildikó Bácskay, László Horváth
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Epilepsy is a widespread disease requiring long-term drug treatment. The aim of this study was to collect information on reported suspected adverse drug reactions (sADRs) of antiseizure medications (ASMs) and study their seriousness and
Externí odkaz:
https://doaj.org/article/d0b5af69826646cf8a139b47e84ef414
Publikováno v:
Medicina, Vol 60, Iss 8, p 1299 (2024)
Background and Objectives: Oxidative stress resulting from a disturbance of the endogenous redox system is suspected in numerous diseases of the central nervous system, including epilepsy. In addition, antiseizure medications (ASMs), especially those
Externí odkaz:
https://doaj.org/article/e12b4dc903914efb8f0758ed18d81b43
Publikováno v:
Journal of Medical and Scientific Research, Vol 11, Iss 4, Pp 329-335 (2023)
Long-term therapy with antiseizure medications (ASMs) has been associated with metabolic consequences that lead to an increase in the risk of atherosclerosis in patients with epilepsy. This study was conducted to assess the effects of ASMs on vascula
Externí odkaz:
https://doaj.org/article/5a15f020c47147ff8f03463ecf5d57c0
Autor:
Maenia Scarpino, Antonello Grippo, Silvia Campagnini, Bahia Hakiki, Antonio Maiorelli, Alessandro Sodero, Erika Guolo, Andrea Mannini, Claudio Macchi, Francesca Cecchi
Publikováno v:
Epilepsy & Behavior Reports, Vol 28, Iss , Pp 100713- (2024)
In stroke survivors, persistent seizure activity could be associated with poor functional outcomes. At the same time, antiepileptic over-treatment could hamper post-stroke recovery. We systematically investigated the occurrence of seizures, the preva
Externí odkaz:
https://doaj.org/article/1e45063377b943d1a7b6a9f03d40c5ff
Autor:
Ya Zeng, Xintong Wu
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
PurposeTo investigate whether there exists a statistically significant distinction between the effectiveness and tolerance of perampanel (PER) and the number of antiseizure medications (ASMs) that were tried prior to administering PER.MethodA prospec
Externí odkaz:
https://doaj.org/article/04678557b2d946a692e38eb089820bb8
Autor:
Cheng‐Yen Kuo, Chang‐Fu Kuo, Lai‐Chu See, Meng‐Jiung Chiou, Po‐Cheng Hung, Jainn‐Jim Lin, Kuang‐Lin Lin, Huei‐Shyong Wang, I‐Jun Chou
Publikováno v:
Brain and Behavior, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Purpose Our objective was to assess the adverse outcomes during pregnancy, as well as for the fetus and neonates, in women with epilepsy, both with and without the use of antiseizure medications (ASMs). Methods A cohort of singleton pregnanc
Externí odkaz:
https://doaj.org/article/72f7da08bc8d44e0b534ca1438581d1c
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