Zobrazeno 1 - 10
of 37
pro vyhledávání: '"ASM Iskander"'
CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma
Autor:
Kartik Angara, Thaiz F. Borin, Mohammad H. Rashid, Iryna Lebedyeva, Roxan Ara, Ping-Chang Lin, ASM Iskander, Roni J. Bollag, Bhagelu R. Achyut, Ali S. Arbab
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 10, Pp 1070-1082 (2018)
BACKGROUND: Glioblastoma (GBM) was shown to relapse faster and displayed therapeutic resistance to antiangiogenic therapies (AATs) through an alternative tumor cell-driven mechanism of neovascularization called vascular mimicry (VM). We identified hi
Externí odkaz:
https://doaj.org/article/41d3f116adab4179ab365cd6ef978c71
Autor:
Vidyavathi Reddy, Asm Iskander, Clara Hwang, George Divine, Mani Menon, Evelyn R Barrack, G Prem-Veer Reddy, Sahn-Ho Kim
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0211090 (2019)
Telomere stability is important for cell viability, as cells with telomere DNA damage that is not repaired do not survive. We reported previously that androgen receptor (AR) antagonist induces telomere DNA damage in androgen-sensitive LNCaP prostate
Externí odkaz:
https://doaj.org/article/607ad49b375c445eb2d9bad612ef676d
Autor:
Thaiz F Borin, Adarsh Shankar, Kartik Angara, Mohammad H Rashid, Meenu Jain, Asm Iskander, Roxan Ara, Iryna Lebedyeva, Hasan Korkaya, Bhagelu R Achyut, Ali S Arbab
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178830 (2017)
Distant metastasis is the primary cause of death in the majority of the cancer types. Recently, much importance has been given to tumor microenvironment (TME) in the development of invasive malignant tumors, as well as the metastasis potential. The a
Externí odkaz:
https://doaj.org/article/e56cd515e4124672bc67342fa6a0f07b
Publikováno v:
Journal of Stem Cells and Regenerative Medicine, Vol 7, Iss 1, Pp 41-53 (2011)
Key words:Cord blood stem cells (AC133+), Lentiviral vectors, Promoters and Green fluorescent protein (GFP). AbstractHuman hematopoietic stem cells (hHSCs) have enormous potential for clinical use in cell-based therapies, especially as a gene deliver
Externí odkaz:
https://doaj.org/article/93528a570ae2446aa7bca0f834adbe25
Publikováno v:
BioTechniques, Vol 43, Iss 5, Pp 627-636 (2007)
Cell labeling with superparamagnetic iron oxides (SPIO) is becoming a routine procedure in cellular magnetic resonance imaging (MRI). Quantifying the intracellular iron in labeled cells is a prerequisite for determining the number of accumulated cell
Externí odkaz:
https://doaj.org/article/ffe1369c4a704d25a9da2fcea82601c7
Autor:
Evelyn R. Barrack, Asm Iskander, Clara Hwang, Sahn-Ho Kim, Mani Menon, George Divine, Vidyavathi Reddy, G. Prem Veer Reddy
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0211090 (2019)
BASE-Bielefeld Academic Search Engine
PLoS ONE
BASE-Bielefeld Academic Search Engine
PLoS ONE
Telomere stability is important for cell viability, as cells with telomere DNA damage that is not repaired do not survive. We reported previously that androgen receptor (AR) antagonist induces telomere DNA damage in androgen-sensitive LNCaP prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6096cd53cd106414bc6c74b341f1613f
https://doaj.org/article/607ad49b375c445eb2d9bad612ef676d
https://doaj.org/article/607ad49b375c445eb2d9bad612ef676d
Autor:
Meshal Alsulami, Thaiz F. Borin, Bhagelu R. Achyut, Austin M. Guo, Meenu Jain, Roxan Ara, Wilson B. Chwang, Asm Iskander, Adarsh Shankar, Iryna Lebedyeva, Mohammad H. Rashid, Hassan Bagher-Ebadian, Ali S. Arbab, Zhi Wenbo, Meser M. Ali, Kartik Angara, Nipuni Dhanesha H Gamage
Publikováno v:
Scientific Reports
Glioblastoma (GBM) is a hypervascular primary brain tumor with poor prognosis. HET0016 is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth. Therefore, to explore novel treatments, we have generated an improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89669dcff9e47f7f4e908efe8c93e84f
https://doi.org/10.1038/srep41809
https://doi.org/10.1038/srep41809
Autor:
Kartik, Angara, Mohammad H, Rashid, Adarsh, Shankar, Roxan, Ara, Asm, Iskander, Thaiz F, Borin, Meenu, Jain, Bhagelu R, Achyut, Ali S, Arbab
Publikováno v:
Histology and histopathology. 32(9)
Glioblastoma (GBM) is one hypervascular and hypoxic tumor known among solid tumors. Antiangiogenic therapeutics (AATs) have been tested as an adjuvant to normalize blood vessels and control abnormal vasculature. Evidence of relapse exemplified in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4e6ed9cdcdd6faae60fdb3ef5564bac
https://pubmed.ncbi.nlm.nih.gov/27990624
https://pubmed.ncbi.nlm.nih.gov/27990624
Autor:
Ali S. Arbab, Bhagelu R. Achyut, Asm Iskander, Meenu Jain, Kartik Angara, Mohammad H. Rashid, Thaiz F. Borin, Roxan Ara, Adarsh Shankar
Publikováno v:
Cancer Research. 77:1043-1043
Exosomes are small vesicle cellular products originating from the endocytic pathway abundantly secreted by tumor cells. These exosomes have the ability to alter their immediate microenvironment (ME) through cell-cell interaction by fusion with plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::785cef142ca557627d9076327a907962
https://doi.org/10.1158/1538-7445.am2017-1043
https://doi.org/10.1158/1538-7445.am2017-1043
Autor:
Roxan Ara, Ali S. Arbab, S Shaaban, Asm Iskander, Adarsh Shankar, Kartik Angara, M Alsulami, Hassan Bagher-Ebadian, Meenu Jain, Bhagelu R. Achyut, S A Arbab
Publikováno v:
International journal of cancer research. 12(2)
Antiangiogenic agents caused paradoxical increase in pro-growth and pro-angiogenic factors and caused tumor growth in glioblastoma (GBM). It is hypothesized that paradoxical increase in pro-angiogenic factors would mobilize Bone Marrow Derived Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69c974aaf4621fb930ede0d7bc80398
https://pubmed.ncbi.nlm.nih.gov/27429653
https://pubmed.ncbi.nlm.nih.gov/27429653