Zobrazeno 1 - 10
of 35
pro vyhledávání: '"ASHOK KUMAR JANAKIRAMAN"'
Autor:
Zenli Cheng, Ashok Kumar Janakiraman, Baskaran Gunasekaran, Crystale Lim Siew Ying, Ezanee Azlina Binti Mohamad Hanif, Hanish Singh Jayasingh Chellammal, Sinouvassane Djearamane
Publikováno v:
Pharmaceutical Sciences, Vol 30, Iss 4, Pp 398-422 (2024)
Zinc oxide nanoparticles (ZnO-NPs) in their many formulations have prompted an immense interest in nanomedicine and drug development. Numerous ZnO-NPs bioactive formulations demonstrate remarkable broad applications in deciphering their therapeutic e
Externí odkaz:
https://doaj.org/article/005edda7012c413fba64098d377e9e58
Autor:
Siti Zaidathul Iman Zolkiffly, Mizaton Hazizul Hasan, Siti Azma Jusoh, Ashok Kumar Janakiraman, Sathesh Kumar Sukumaran, Noreen Husain, Yuslina Zakaria, Hanish Singh Jayasingh Chellammal
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 13, Iss , Pp 100547- (2024)
Background: Amyloid beta (Aβ) plaques on the extracellular matrix and intracellular neurofibrillary tangles comprise the key indicative pathology of Alzheimer's disease (AD). Fisetin, an antioxidant bioactive compound having pharmacotherapeutic effe
Externí odkaz:
https://doaj.org/article/3bcfbf5aaf67469da4350c8471d913db
Autor:
Arunkumar Subramanian, T. Tamilanban, Vetriselvan Subramaniyan, Mahendran Sekar, Vipin Kumar, Ashok Kumar Janakiraman, Saminathan Kayarohanam
Publikováno v:
Toxicology Reports, Vol 13, Iss , Pp 101715- (2024)
Alzheimer’s disease (AD) is a major cause of disability and one of the top causes of mortality globally. AD remains a major public health challenge due to its prevalence, impact on patients and caregivers, and the current lack of a cure. In recent
Externí odkaz:
https://doaj.org/article/04f0b74a32cc4864a307d66dcd51e774
Autor:
Melbha Starlin Chellathurai, Syed Mahmood, Zarif Mohamed Sofian, Cheng Wan Hee, Ramkanth Sundarapandian, Haja Nazeer Ahamed, C. S. Kandasamy, Ayah R. Hilles, Najihah Mohd Hashim, Ashok Kumar Janakiraman
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
AbstractMicroneedle (MN) delivery devices are more accepted by people than regular traditional needle injections (e.g. vaccination) due to their simplicity and adaptability. Thus, patients of chronic diseases like diabetes look for alternative pain-f
Externí odkaz:
https://doaj.org/article/acfcb137b4d541a2864aa3f8fe89eb09
Autor:
Zenli Cheng, Zi Yin Wong, S. Ramkanth, Cheng Wan Hee, Mohamed Saleem TS, Saminathan Kayarohanam, M Yasmin Begum, Kushagra Khanna, Abhishek Kumar, Ashok Kumar Janakiraman
Publikováno v:
OpenNano, Vol 18, Iss , Pp 100210- (2024)
This research descibes a pioneering approach aimed at preparing zinc oxide nanoparticles (ZnO-NPs) with colchicine as the reducing and capping agent. Colchicine-loaded ZnO-NPs (CHZnO-NPs) were prepared by adding colchicine to the zinc sulfate heptahy
Externí odkaz:
https://doaj.org/article/29240f883420457f946247a2b55c224c
Autor:
Saiqa Afroze, Ashok Kumar Janakiraman, Baskaran Gunasekaran, Sinouvassane Djearamane, Ling Shing Wong
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 12, Iss 1, Pp 120-145 (2024)
Context: Eicosapentaenoic acid, docosahexaenoic acid, and docosapentaenoic acid are the significant members of the ω-3 fatty acid group. Their beneficial pharmacological effects open new paths for therapeutics. Aims: To provide an updated overvie
Externí odkaz:
https://doaj.org/article/bbddfe7566e14b8da74444e8d01fdcdb
Autor:
Lobna Shakir Abed Al-Suwayyid, Ashok Kumar Janakiraman, Sharmanee Thiagarajah, Baskaran Gunasekaran, Kushagra Khanna, Abhishek Kumar, Jamal Moideen Muthu Mohamed, Ling Shing Wong
Publikováno v:
Journal of Advanced Pharmaceutical Technology & Research, Vol 14, Iss 4, Pp 325-331 (2023)
Zinc oxide nanoparticles (ZnO-NPs) were synthesized using ginger (Zingiber officinale) extracts in a green synthesis approach and evaluated their in vitro cytotoxicity effect on the MDA-MB 231 breast cancer cell line. The bottom-up approach was emplo
Externí odkaz:
https://doaj.org/article/cbbd7205ab8e48698a6687616140eb4b
Publikováno v:
Beni-Suef University Journal of Basic and Applied Sciences, Vol 11, Iss 1, Pp 1-13 (2022)
Abstract Background Vorinostat is a histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) with anticancer properties. However, it is plagued by low water solubility, low permeability (BCS class IV drug), and suboptimal pharmacokinetics
Externí odkaz:
https://doaj.org/article/d379294370be4339b9a8511b8fc77045
Autor:
Neelakandan Tamilarasan, Begum M. Yasmin, Posina Anitha, Hani Umme, Wan Hee Cheng, Sellapan Mohan, Sundarapandian Ramkanth, Ashok Kumar Janakiraman
Publikováno v:
Nanomaterials, Vol 12, Iss 17, p 2954 (2022)
Transferosomes are one of the vesicular carriers that have received extensive research and attention recently because of their capacity to get beyond the barriers posed by the stratum corneum to penetration. The intent of the current study is to opti
Externí odkaz:
https://doaj.org/article/c0c4453ed126486ab2318337cfa97ddc
Autor:
Jamal Moideen Muthu Mohamed, Ali Alqahtani, Farid Menaa, Saminathan Kayarohanam, Adel Al Fatease, Taha Alqahtani, Ali Alamri, Mohamed El-Sherbiny, Sundarapandian Ramkanth, Ashok Kumar Janakiraman
Publikováno v:
Crystals, Vol 12, Iss 7, p 988 (2022)
The major goal of this investigation was to prepare carvedilol nanocrystals (CRL-NCs) for better solubility, stability, and bioavailability. Using polyvinyl pyrolidine K-30 (PVP) and sodium dodecyl sulphate (SDS) as stabilisers, CRL-NCs were effectiv
Externí odkaz:
https://doaj.org/article/26a89d8123bd4ada8d121e6cf3a488d8