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Autor:
JONATHAN Q. PURNELL, ASHLEY N. GREGOR, DONGSEOK CHOI, ERIC BAETSCHER, WILLIAM ROONEY, CARY O. HARDING, MELANIE B. GILLINGHAM
Publikováno v:
Diabetes. 71
Mitochondrial handling of excess lipid substrate may be an important determinant of insulin resistance. Animal models support insulin signaling defects resulting from both defective fatty acid oxidation (FAO) with subsequent intra-cellular lipid accu