Identification of amygdala-expressed genes associated with autism spectrum disorder

Autor: Maria Jesus Herrero, Dmitry Velmeshev, David Hernandez-Pineda, Saarthak Sethi, Shawn Sorrells, Payal Banerjee, Catherine Sullivan, Abha R. Gupta, Arnold R. Kriegstein, Joshua G. Corbin

Publikováno v: Molecular Autism, Vol 11, Iss 1, Pp 1-14 (2020)

Abstract Background Studies of individuals with autism spectrum disorder (ASD) have revealed a strong multigenic basis with the identification of hundreds of ASD susceptibility genes. ASD is characterized by social deficits and a range of other pheno

Externí odkaz: https://doaj.org/article/4156d40f162a400b9104025a043197f0

Identification of amygdala-expressed genes associated with autism spectrum disorder

Autor: Arnold R. Kriegstein, Maria Jesus Herrero, Catherine Sullivan, David Hernandez-Pineda, Shawn F. Sorrells, Payal Banerjee, Saarthak Sethi, Dmitry Velmeshev, Abha R. Gupta, Joshua G. Corbin

Publikováno v: Molecular Autism, Vol 11, Iss 1, Pp 1-14 (2020)
Molecular Autism
Molecular autism, vol 11, iss 1

Background Studies of individuals with autism spectrum disorder (ASD) have revealed a strong multigenic basis with the identification of hundreds of ASD susceptibility genes. ASD is characterized by social deficits and a range of other phenotypes, im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601d82bc9f55ad2b359d2dd3346db390
http://link.springer.com/article/10.1186/s13229-020-00346-1

Identifying disease genes using machine learning and gene functional similarities, assessed through Gene Ontology

Autor: Asif, M., Martiniano, H.F.M.C.M., Vicente, A.M., Couto, F.M.

Identifying disease genes from a vast amount of genetic data is one of the most challenging tasks in the post-genomic era. Also, complex diseases present highly heterogeneous genotype, which difficult biological marker identification. Machine learnin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2016::615447a09dcfc339ad7112ae1925a98d
https://hdl.handle.net/10400.18/5930

Morphometric Analysis of Recognized Genes for Autism Spectrum Disorders and Obesity in Relationship to the Distribution of Protein-Coding Genes on Human Chromosomes

Autor: Ann M. Manzardo, Syed K. Rafi, Merlin G. Butler, Austen McGuire

Publikováno v: International Journal of Molecular Sciences; Volume 17; Issue 5; Pages: 673
International Journal of Molecular Sciences, Vol 17, Iss 5, p 673 (2016)
International Journal of Molecular Sciences

Mammalian chromosomes are comprised of complex chromatin architecture with the specific assembly and configuration of each chromosome influencing gene expression and function in yet undefined ways by varying degrees of heterochromatinization that res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc604d428cdb2bf954076d615b1d4c77

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