Zobrazeno 1 - 10
of 113
pro vyhledávání: '"ARNOLD J. BERK"'
Autor:
Hideki Ando, Tomomi Sato, Takumi Ito, Junichi Yamamoto, Satoshi Sakamoto, Nobuhiro Nitta, Tomoko Asatsuma-Okumura, Nobuyuki Shimizu, Ryota Mizushima, Ichio Aoki, Takeshi Imai, Yuki Yamaguchi, Arnold J. Berk, Hiroshi Handa
Publikováno v:
iScience, Vol 15, Iss , Pp 95-108 (2019)
Summary: Thalidomide is a teratogen that causes multiple malformations in the developing baby through its interaction with cereblon (CRBN), a substrate receptor subunit of the CRL4 E3 ubiquitin ligase complex. CRBN was originally reported as a gene a
Externí odkaz:
https://doaj.org/article/60af45cc9cbd4bfbaae5aca5b107477a
Publikováno v:
eLife, Vol 10 (2021)
Regulation of RNA polymerase II (Pol2) elongation in the promoter-proximal region is an important and ubiquitous control point for gene expression in metazoans. We report that transcription of the adenovirus 5 E4 region is regulated during the releas
Externí odkaz:
https://doaj.org/article/3b7ab3a331a741e2a3d39d4b70dd79c1
Autor:
Tomoko Asatsuma-Okumura, Ichio Aoki, Ryota Mizushima, Junichi Yamamoto, Takumi Ito, Arnold J. Berk, Satoshi Sakamoto, Tomomi Sato, Takeshi Imai, Nobuhiro Nitta, Hideki Ando, Nobuyuki Shimizu, Yuki Yamaguchi, Hiroshi Handa
Publikováno v:
iScience, Vol 15, Iss, Pp 95-108 (2019)
iScience
iScience
Summary Thalidomide is a teratogen that causes multiple malformations in the developing baby through its interaction with cereblon (CRBN), a substrate receptor subunit of the CRL4 E3 ubiquitin ligase complex. CRBN was originally reported as a gene as
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Regulation of RNA polymerase II (Pol2) elongation in the promoter-proximal region is an important and ubiquitous control point for gene expression in metazoans. We report that transcription of the adenovirus 5 E4 region is regulated during the releas
SummaryRegulation of RNA Polymerase II (Pol2) elongation in the promoter proximal region is an important and ubiquitous control point for gene expression in metazoan cells. We report that transcription of the adenovirus 5 E4 region is regulated durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c1ea47300d12398ac42b28c4a643dc3
https://doi.org/10.1101/2020.09.26.315002
https://doi.org/10.1101/2020.09.26.315002
Publikováno v:
Genesdevelopment. 33(13-14)
Adenovirus transformed cells have a dedifferentiated phenotype. Eliminating E1A in transformed human embryonic kidney cells derepressed ∼2600 genes, generating a gene expression profile closely resembling mesenchymal stem cells (MSCs). This was ass
Publikováno v:
Journal of virology, vol 92, iss 18
How histone acetylation promotes transcription is not clearly understood. Here, we confirm an interaction between p300 and the adenovirus 2 large E1A activation domain (AD) and map the interacting regions in E1A by observing colocalization at an inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dffc20edb5efbda50fd00276396f54b
https://escholarship.org/uc/item/2js2d5dd
https://escholarship.org/uc/item/2js2d5dd
Autor:
Reza Kalhor, Frank Alber, Trent Su, Haochen Li, Lin Chen, Arnold J. Berk, Siavash K. Kurdistani, Bing Li
Viruses have evolved a variety of mechanisms to interact with host cells for their adaptive benefits, including subverting host immune responses and hijacking host DNA replication/transcription machineries [1–3]. Although interactions between viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d9f6a62816f0e270884e4bb432b009
https://doi.org/10.1101/142604
https://doi.org/10.1101/142604
Autor:
Arnold J. Berk, Matteo Pellegrini, Siavash K. Kurdistani, Sarah A. Johnson, Trent Su, Miguel Nava, Nathan R. Zemke, Gauri W. Jawdekar, Roberto Ferrari, Ahmed F. Yousef, Dawei Gou
Publikováno v:
Cell host & microbe, vol 16, iss 5
Summary Oncogenic transformation by adenovirus small e1a depends on simultaneous interactions with the host lysine acetylases p300/CBP and the tumor suppressor RB. How these interactions influence cellular gene expression remains unclear. We find tha