Zobrazeno 1 - 10
of 1 247
pro vyhledávání: '"ARMS-PCR"'
Genotyping single point mutations in rd1 and rd8 mice using melting curve analysis of qPCR fragments
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract PCR is tolerant to single nucleotide mismatches. Therefore, genotyping of point mutations by PCR requires special conditions for the amplification of allele-specific PCR fragments. MS-PCR (mutagenically separated PCR) is an improved version
Externí odkaz:
https://doaj.org/article/7f5088d57eff44bcbd82ac0d94c6c0fa
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract The parallel rise in obesity and male infertility in modern societies necessitates the identification of susceptibility genes underlying these interconnected health issues. In our study, we conducted a comprehensive search in the OMIM databa
Externí odkaz:
https://doaj.org/article/f42e578b13ba459383b6026b4cd2541b
Publikováno v:
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 32, Iss 1, Pp 7416-7427 (2024)
Introduction: The TP53 gene on the short arm of chromosome 17p, which is known as a tumor suppressor gene, encodes the transcription factor p53, and this factor controls cell cycle progression. This study was done to assess the association of TP53 (r
Externí odkaz:
https://doaj.org/article/d908d435b5664ab98c7f078dbe8488c0
Autor:
Atiyeh Mellati, Samaneh Soltani, Tohid Kazemi, Nooshin Ahmadzadeh, Maryam Akhtari, Elham Madreseh, Ahmadreza Jamshidi, Elham Farhadi, Mahdi Mahmoudi
Publikováno v:
BMC Rheumatology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract Background Through investigating genetic variations, it has been demonstrated that single nucleotide polymorphisms (SNPs) in the IL-23 receptor (IL23R) gene have a critical role in the pathophysiology of ankylosing spondylitis (AS). Here, we
Externí odkaz:
https://doaj.org/article/69ae0f6a2f744b5b9b19ca07f71c5bd0
Autor:
Saeied Malekzadeh, Sara Ghaffarian
Publikováno v:
Iranian South Medical Journal, Vol 26, Iss 3, Pp 155-166 (2024)
Background: The MisMatch Repair (MMR) system is a conserved system with a key role in genetic stability and replication integrity. The MLH1 gene is one of the four main components of the MMR complex. This study was conducted to assess the association
Externí odkaz:
https://doaj.org/article/efe4cc4cda9a4a569f11a48ff57a7a24
Autor:
Maryam Nawab, Syeda Kiran Riaz, Eiman Ismail, Alfar Ahamed, Aaysha Tariq, Muhammad Faraz Arshad Malik, Naeem F. Qusty, Farkad Bantun, Petr Slama, Massab Umair, Shafiul Haque, D. Katterine Bonilla-Aldana, Alfonso J. Rodriguez-Morales
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Global impact of COVID-19 pandemic has heightened the urgency for efficient virus detection and identification of variants such as the Q57H mutation. Early and efficient detection of SARS-CoV-2 among densely populated developing countries is
Externí odkaz:
https://doaj.org/article/a250d108a6de473faed6707169a9f910
Autor:
Mohammad Reza Mirinezhad, Maliheh Aghsizadeh, Hamideh Ghazizadeh, Sahar Ghoflchi, Mohammad Zamiri Bidary, Alireza Naghipour, Gordon A. Ferns, Tayebeh Hamzehloei, Alireza Pasdar, Majid Ghayour-Mobarhan
Publikováno v:
BMC Women's Health, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background and aim premature ovarian insufficiency (POI) is defined as the menopause before 40 years of age, and its prevalence is reported to be two-fold higher in Iranian women than the average for woman globally. POI is associated with se
Externí odkaz:
https://doaj.org/article/b21b66d8fd694a58b9785684314e4265
Autor:
Atefeh Rahimi, Nastaran Moridi, Amin Golestani, Gholamreza Anani-Sarab, Fatemeh Salmani, Gholamhossein Yaqubi, Behzad Mesbahzadeh, Mohammad Ali Jalalifar, Mohammad Malekaneh, Seyed Mehdi Sajjadi
Publikováno v:
Caspian Journal of Internal Medicine, Vol 15, Iss 1, Pp 101-108 (2024)
Background: Diabetic retinopathy (DR) is expanding to epidemic levels globally due to the progressing prevalence of diabetes mellitus (DM). In this study, the association between factor V Leiden (FVL), MTHFRC677T, and FXIIIVal34Leu polymorphisms and
Externí odkaz:
https://doaj.org/article/f0de77313f9f4698ba6fe794edf10b8f
Autor:
Duong Bich Tram, Ho Quoc Chuong, Huynh Anh Phuong, Nguyen The Nguyen Phung, Mai-Lan Nguyen, Hoang Anh Vu
Publikováno v:
Journal of Laboratory Physicians, Vol 15, Iss 04, Pp 567-572 (2023)
Objective The NUDT15 variants impact thiopurine dose selection in acute lymphoblastic leukemia patients. The ability to rapidly detect variants is important in clinical practice. This study aims to develop a simple polymerase chain reaction (PCR) pro
Externí odkaz:
https://doaj.org/article/a6578879660648f3b479227d51b244ed
Autor:
P. J. Wijekumar, N. D.K. Ranadeva, A. R. Jayamaha, H. M.N.D.M. Herath, N. Noorden, S. S.N. Fernando
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Objectives A SNV is a single nucleotide change that can occur at any point in the genome. SNVs are the most common genetic variants that occur in the human genome, and a number of SNVs have been found to be associated with human traits and d
Externí odkaz:
https://doaj.org/article/8ca79d466f254f8cb71a594a002e6e5a