Zobrazeno 1 - 10
of 96
pro vyhledávání: '"ARID5A"'
Publikováno v:
Translational Oncology, Vol 42, Iss , Pp 101900- (2024)
Resistance to chimeric antigen receptor (CAR) T-cell therapy remains a significant challenge in the treatment of solid tumors. This resistance is attributed to various factors, including antigen loss, immunosuppressive tumor microenvironment, and upr
Externí odkaz:
https://doaj.org/article/e607f019b1264fb99f832218a1d11324
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Currently, there is lack of marker to accurately assess the prognosis of patients diagnosed with pancreatic ductal adenocarcinoma (PDAC). This study aims to establish a hypoxia-related risk scoring model that can effectively predi
Externí odkaz:
https://doaj.org/article/8cee42d46b014909bbe3ad1e5f714ab3
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 813-824 (2023)
AT-rich interactive domain 5a (Arid5a) is a member of the arid family of proteins, which contain a helix-turn-helix domain and an ability to bind to nucleic acids. Current evidence suggests that Arid5a performs dual functions as a transcription facto
Externí odkaz:
https://doaj.org/article/5d1f6696fd754b558fee342cc438dba6
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 9, Pp 2056-2066 (2023)
The key regulators and regeneration-associated genes involved in axonal regeneration of neurons after injury have not been clarified. In high-throughput sequencing, various factors influence the final sequencing results, including the number and size
Externí odkaz:
https://doaj.org/article/40bf515bad41451cb91fe2f72a3fb285
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Background The microarray data analysis predicted that Rbpjl is poorly expressed in acute pancreatitis (AP). Activated IL-6/STAT3 signaling is further known to contribute to the progression of AP through immune regulation, and both IL-6 and
Externí odkaz:
https://doaj.org/article/2dea36fae0fe4cbbb9f0bd99c7f57224
Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is the most fatal cancer in humans, due to its difficulty of early detection and its high metastatic ability. The occurrence of epithelial to mesenchymal transition in preinvasive pancreatic lesions has been im
Externí odkaz:
https://doaj.org/article/7c66e1587aea44468a0cbcfe38fcfa61
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Abdullah Alzahrani, Hamza Hanieh
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 12, Pp 1605-1615 (2020)
Multiple sclerosis (MS) is an autoimmune disease that involves demyelination of axons in the central nervous system (CNS) and affects patients worldwide. It has been demonstrated that ligand-activated aryl hydrocarbon receptor (Ahr) ameliorates exper
Externí odkaz:
https://doaj.org/article/7aa05ecec8164bbf89efde430a27625a
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
AT-rich interactive domain 5a (Arid5a) is a nucleic acid binding protein. In this review, we highlight recent advances in the association of Arid5a with inflammation and human diseases. Arid5a is known as a protein that performs dual functions. In in
Externí odkaz:
https://doaj.org/article/fb1e7a0364eb488dbb38bcfc6f47c664