Zobrazeno 1 - 10
of 19
pro vyhledávání: '"ARIANE MORA"'
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-26 (2024)
Abstract Background Clear cell renal cell carcinoma (ccRCC) tumours develop and progress via complex remodelling of the kidney epigenome, transcriptome, proteome and metabolome. Given the subsequent tumour and inter-patient heterogeneity, drug-based
Externí odkaz:
https://doaj.org/article/c0ffeed62cb74c2e87e0394d0b82398f
Autor:
Connor Rogerson, Marco Sciacovelli, Lucas A. Maddalena, Andromachi Pouikli, Marc Segarra-Mondejar, Lorea Valcarcel-Jimenez, Christina Schmidt, Ming Yang, Elena Ivanova, Joshua Kent, Ariane Mora, Danya Cheeseman, Jason S. Carroll, Gavin Kelsey, Christian Frezza
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112751- (2023)
Summary: Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a cancer syndrome caused by inactivating germline mutations in fumarate hydratase (FH) and subsequent accumulation of fumarate. Fumarate accumulation leads to profound epigenetic cha
Externí odkaz:
https://doaj.org/article/4a018807958940d294037e2083e5da34
Autor:
Gabriel Foley, Ariane Mora, Connie M Ross, Scott Bottoms, Leander Sützl, Marnie L Lamprecht, Julian Zaugg, Alexandra Essebier, Brad Balderson, Rhys Newell, Raine E S Thomson, Bostjan Kobe, Ross T Barnard, Luke Guddat, Gerhard Schenk, Jörg Carsten, Yosephine Gumulya, Burkhard Rost, Dietmar Haltrich, Volker Sieber, Elizabeth M J Gillam, Mikael Bodén
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 10, p e1010633 (2022)
Ancestral sequence reconstruction is a technique that is gaining widespread use in molecular evolution studies and protein engineering. Accurate reconstruction requires the ability to handle appropriately large numbers of sequences, as well as insert
Externí odkaz:
https://doaj.org/article/6706c45e0af54c36a70246e9e790f19a
Autor:
Lorea Valcarcel-Jimenez, Connor Rogerson, Cissy Yong, Christina Schmidt, Ming Yang, Monica Cremades-Rodelgo, Victoria Harle, Victoria Offord, Kim Wong, Ariane Mora, Alyson Speed, Veronica Caraffini, Maxine Gia Binh Tran, Eamonn R. Maher, Grant D. Stewart, Sakari Vanharanta, David J. Adams, Christian Frezza
Publikováno v:
Science Advances. 8
Fumarate hydratase (FH) is a mitochondrial enzyme that catalyzes the reversible hydration of fumarate to malate in the tricarboxylic acid (TCA) cycle. Germline mutations of FH lead to hereditary leiomyomatosis and renal cell carcinoma (HLRCC), a canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e25b92f275d4c9db74028e103d2d9b90
https://doi.org/10.1126/sciadv.abq8297
https://doi.org/10.1126/sciadv.abq8297
Autor:
Connor Rogerson, Marco Sciacovelli, Lucas A Maddalena, Lorea Valcarcel-Jimenez, Christina Schmidt, Ming Yang, Elena Ivanova, Joshua Kent, Ariane Mora, Danya Cheeseman, Jason S Carroll, Gavin Kelsey, Christian Frezza
Hereditary Leiomyomatosis and renal cell cancer (HLRCC) is a cancer syndrome caused by inactivating germline mutations in fumarate hydratase (FH) and subsequent accumulation of fumarate. Fumarate accumulation leads to the activation of an anti-oxidan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d597dfc3cdcb4747096b4dc97bc774c6
https://doi.org/10.1101/2022.07.04.498412
https://doi.org/10.1101/2022.07.04.498412
Publikováno v:
Briefings in bioinformatics. 23(6)
Accurately identifying cell-populations is paramount to the quality of downstream analyses and overall interpretations of single-cell RNA-seq (scRNA-seq) datasets but remains a challenge. The quality of single-cell clustering depends on the proximity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad29367d8c3e76175ec549f705010ae
https://pubmed.ncbi.nlm.nih.gov/36151725
https://pubmed.ncbi.nlm.nih.gov/36151725
Accurately identifying cell populations is paramount to the quality of downstream analyses and overall interpretations of single-cell RNA-seq (scRNA-seq) datasets but remains a challenge. The quality of single-cell clustering depends on the proximity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::139f39a3ace94c411198cf57475122c9
https://doi.org/10.1101/2022.04.21.489121
https://doi.org/10.1101/2022.04.21.489121
Autor:
Ariane Mora, Jonathan Rakar, Ignacio Monedero Cobeta, Behzad Yaghmaeian Salmani, Annika Starkenberg, Stefan Thor, Mikael Bodén
A prominent aspect of most, if not all, central nervous systems (CNSs) is that anterior regions (brain) are larger than posterior ones (spinal cord). Studies in Drosophila and mouse have revealed that Polycomb Repressor Complex 2 (PRC2), a protein co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f91e1c7d2a3b8bb2661a8f81df6046e
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-183915
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-183915
Autor:
Scott Bottoms, Marnie L. Lamprecht, Luke W. Guddat, Jörg Carsten, Volker Sieber, Ariane Mora, Alexandra Essebier, Bostjan Kobe, Brad Balderson, Connie M. Ross, Raine E. S. Thomson, Elizabeth M. J. Gillam, Leander Sützl, Rhys Newell, Burkhard Rost, G. Foley, Julian Zaugg, Ross Barnard, Dietmar Haltrich, Mikael Bodén, Gerhard Schenk, Yosephine Gumulya
Ancestral sequence reconstruction is a technique that is gaining widespread use in molecular evolution studies and protein engineering. Accurate reconstruction requires the ability to handle appropriately large numbers of sequences, as well as insert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::201cef017b0beb84465a5ba6f740229a
https://doi.org/10.1101/2019.12.30.891457
https://doi.org/10.1101/2019.12.30.891457
Autor:
Mosbergen, Rowland, ISHA NAGPAL, Korn, Othmar, ARIANE MORA, TYRONE CHEN, CHRIS PACHECO RIVERA, CHRISTINE WELLS
http://dx.doi.org/10.6084/m9.figshare.10099412Stemformatics [1] (www.stemformatics.org) is primarily a web-based pocket dictionary for stem cells biologists running on the NeCTAR cloud [2]. Part of the stem cell community for over 6 years, it allows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e4ed9451d464efd0306fba83fb0871