Prognosis biomarker and potential therapeutic target CRIP2 associated with radiosensitivity in NSCLC cells

Autor: Wei-Qiang Chen, Xiaodong Jin, Liu Yan, Feifei Li, Fei Ye, Zhitong Bing, Lan Ding

Publikováno v: Biochemical and Biophysical Research Communications. 584:73-79

Radiotherapy plays a major role in non-small cell lung cancer (NSCLC) treatment. The curative efficacy of advanced NSCLC is unsatisfactory because of its radioresistance to conventional radiotherapy. The biomarkers which can be used to diagnose radio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1b0a67e8b01786cea76686edf09916
https://doi.org/10.1016/j.bbrc.2021.11.002

KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1

Autor: Shouzhen Chen, Jianfeng Cui, Lipeng Chen, Yangyang Xia, Benkang Shi, Lei Liu, Yong Wang, Yongxin Zou, Shuna Sun, Xiaochen Liu, Yajing Zhao

Publikováno v: Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Molecular Cancer

Background KDM6A, a histone demethylase, is frequently mutated in bladder cancer (BCa). However, the role and detailed molecular mechanism of KDM6A involved in bladder cancer progression remains unknown. Methods Tissue specimens were used to determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a5dc1272723340a7b860dd80a16d7e
https://doaj.org/article/cb1c6feaaf5b4ad19930e456bf63cf46

Systematic investigation of biomarker-like role of ARHGDIB in breast cancer

Autor: Xing Huang, Xiao-Min Bi, Xiaonan Wang, Bijun Wang, Qianying Guo, Zhengsheng Wu

Publikováno v: Cancer Biomarkers. 28:101-110

Background ARHGDIB, a Rho GDP dissociation inhibitor protein, has been reported playing critical roles in regulation of multiple biological responses. However, whether ARHGDIB serves as a valuable biomarker in cancer is little known so far, especiall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a45d0e28a0a1527a5ebd7caf2bc22d4
https://doi.org/10.3233/cbm-190562

ARHGDIB Plays a Novel Role in the Braak Stages of Alzheimer's Diseases via the Immune Response Mediated by Microglia

Autor: Huitao Tang, Keping Chai, Daojiang Shen, Jiwei Liang, Xiaolin Zhang, Panlong Cao, Weiping Ye, Shufang Chen, Huaqian Gu, Jingjing Liu, Gang Logan Liu, Feng Wan

Background: Aberrant neurofibrillary tangles (NFT) deposits is a mainly character of Alzheimer's diseases (AD). A lot of evidence shows that at different stages of AD, the distribution region of NFT in the brain is also different. For example, the en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aed8d91c726907afb269b32bf6fe3dd5
https://doi.org/10.21203/rs.3.rs-474315/v1

Antibodies against ARHGDIB are associated with long-term kidney graft loss

Autor: Karlijn A M I van der Pant, Michiel G. H. Betjes, Elena G. Kamburova, Irma Joosten, Jan-Stephan F. Sanders, Laura Bungener, Henny G. Otten, Bram W. Wisse, Adriaan C.A.D. Drop, Elly M. van Duijnhoven, Franka E. van Reekum, Maartje L Gruijters, Mariëlle A C J Gelens, Maarten H. L. Christiaans, Wendy Swelsen, Marc A. Seelen, Sebastiaan Heidt, Johan W. de Fijter, Cornelis E. Hack, Shaikh A. Nurmohamed, Michiel L. Bots, Loes Plaisier, Frederike J. Bemelman, Annechien J. A. Lambeck, Luuk B. Hilbrands, Bouke G. Hepkema, Arjan D. van Zuilen, Frans J. van Ittersum, Andries J. Hoitsma, Neelke C. van der Weerd, Marianne C. Verhaar, Frans H.J. Claas, Eric Spierings, N M Lardy, Paul J M van der Boog, Marije C. Baas, Arnold van der Meer, Tineke Kardol-Hoefnagel, Ineke J. M. ten Berge, Dave L. Roelen, Marcel G.J. Tilanus, Wil A. Allebes, Lotte Wieten, Rowena C A Melchers, Caroline Roozendaal, Christina E.M. Voorter

Publikováno v: American Journal of Transplantation
American Journal of Transplantation, 19(12), 3335. Blackwell Publishing Asia Pty Ltd
American Journal of Transplantation, 19(12), 3335-3344. Wiley-Blackwell
Kamburova, E G, Gruijters, M L, Kardol-Hoefnagel, T, Wisse, B W, Joosten, I, Allebes, W A, van der Meer, A, Hilbrands, L B, Baas, M C, Spierings, E, Hack, C E, van Reekum, F E, van Zuilen, A D, Verhaar, M C, Bots, M L, Drop, A C A D, Plaisier, L, Melchers, R C A, Seelen, M A J, Sanders, J S, Hepkema, B G, Lambeck, A J A, Bungener, L B, Roozendaal, C, Tilanus, M G J, Voorter, C E, Wieten, L, van Duijnhoven, E M, Gelens, M A C J, Christiaans, M H L, van Ittersum, F J, Nurmohamed, S A, Lardy, N M, Swelsen, W, van der Pant, K A M I, van der Weerd, N C, ten Berge, I J M, Hoitsma, A, van der Boog, P J M, de Fijter, J W, Betjes, M G H, Heidt, S, Roelen, D L, Claas, F H, Bemelman, F J & Otten, H G 2019, ' Antibodies against ARHGDIB are associated with long-term kidney graft loss ', American Journal of Transplantation, vol. 19, no. 12, pp. 3335-3344 . https://doi.org/10.1111/ajt.15493
American Journal of Transplantation, 19, 12, pp. 3335-3344
American journal of transplantation, 19(12), 3335-3344. Wiley-Blackwell
American Journal of Transplantation. Wiley
American Journal of Transplantation, 19(12), 3335-3344. Wiley
American Journal of Transplantation. Wiley-Blackwell Publishing Ltd
American Journal of Transplantation, 19(12), 3335-3344
American Journal of Transplantation, 19, 3335-3344

The clinical significance of non‐HLA antibodies on renal allograft survival is a matter of debate, due to differences in reported results and lack of large‐scale studies incorporating analysis of multiple non‐HLA antibodies simultaneously. We d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2e8eaf33d5c28fbce044c2f8087531
https://dspace.library.uu.nl/handle/1874/391689