Analysis of the intronic single nucleotide polymorphism rs#466452 of the nephrin gene in patients with diabetic nephropathy

Autor: RODRIGO GONZÁLEZ, ARES TIRADO, LUIS A ROJAS, FRANCISCO J OSSANDÓN, MIRIAM ALVO, CARLOS WOLFF, DANIELA SEELENFREUND, PILAR DURRUTY, SERGIO LOBOS

Publikováno v: Biological Research, Vol 42, Iss 2, Pp 189-198 (2009)

We present the analysis of an intronic polymorphism of the nephrin gene and its relationship to the development of diabetic nephropathy in a study of diabetes type 1 and type 2 patients. The frequency of the single nucleotide polymorphism rs#466452 i

Externí odkaz: https://doaj.org/article/089f7307ee504c1fa84d7fc07188e568

A pilot study on genetic variation in purine-rich elements in the nephrin gene promoter in type 2 diabetic patients

Autor: Miriam Alvo, Ares Tirado, Monserrat Balanda, Sergio Lobos, Durruty P, Rodrigo González, Inés Barquín, Daniela Seelenfreund

Publikováno v: Biological Research, Vol 40, Iss 3, Pp 357-364 (2007)
Biological Research v.40 n.3 2007
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Volume: 40, Issue: 3, Pages: 357-364, Published: 2007

Diabetic nephropathy (DN) is one of the major complications of type 2 diabetes and is associated with coronary disease. Nephrin, a protein mainly expressed in glomeruli, is decreased in DN and other kidney diseases. Since insulin levels are misregula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efab125f3f43e19b1e221097b7acf4d7
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000400010