Zobrazeno 1 - 10
of 6 522
pro vyhledávání: '"AR binding"'
Publikováno v:
Journal of Clinical Oncology; 2024 Supplement 4, Vol. 42, p42-42, 235p
Autor:
Nash, Claire, Boufaied, Nadia, Mills, Ian G., Franco, Omar E., Hayward, Simon W., Thomson, Axel A.
Publikováno v:
In Molecular and Cellular Endocrinology 15 August 2018 471:1-14
Autor:
Baylee A. Porter, Xiang Li, Neeru Arya, Fan Zhang, Sonia H.Y. Kung, Ladan Fazli, Htoo Zarni Oo, Yinan Li, Kenneth Marincin, Konsta Kukkonen, Henna Urhonen, Maria A. Ortiz, Allysa P. Kemraj, Eva Corey, Xuesen Dong, Vladimir A. Kuznetsov, Matti Nykter, Martin E. Gleave, Gennady Bratslavsky, Alfonso Urbanucci, Dominique Frueh, Alaji Bah, Leszek Kotula
Transcription regulates key functions of living organisms in normal and disease states, including cell growth and development, embryonic and adult tissue organization, and tumor progression. Here we identify a novel mechanism of transcriptional regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a432621e95cbfe991ae0315337679352
https://doi.org/10.1101/2023.05.26.542350
https://doi.org/10.1101/2023.05.26.542350
Akademický článek
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Autor:
Guo, Ju1 (AUTHOR), Wei, Zhao2 (AUTHOR), Jia, Tianwei3,4,5 (AUTHOR), Wang, Liyang6,7 (AUTHOR), Nama, Nuosu6,8 (AUTHOR), Liang, Jiaqian9 (AUTHOR), Liao, Xinghua10 (AUTHOR), Liu, Xiaming11 (AUTHOR), Gao, Yanfei12 (AUTHOR), Liu, Xiaoqiang1 (AUTHOR), Wang, Keshan6,13,14 (AUTHOR) wks4869@hust.edu.cn, Fu, Bin1 (AUTHOR) urofbin@163.com, Chen, Shaoyong Shawn1,6 (AUTHOR) shaoyong_chen@hotmail.com
Publikováno v:
Journal of Translational Medicine. 10/12/2023, Vol. 21 Issue 1, p1-17. 17p.
Publikováno v:
SAR and QSAR in Environmental Research. 27:303-316
A fundamental element when deriving a robust and predictive in silico model is not only the statistical quality of the model in question but, equally important, the estimate of its predictive boundaries. This work presents a new method, conformal pre
Autor:
Ju Guo, Zhao Wei, Tianwei Jia, Liyang Wang, Nuosu Nama, Jiaqian Liang, Xinghua Liao, Xiaming Liu, Yanfei Gao, Xiaoqiang Liu, Keshan Wang, Bin Fu, Shaoyong Shawn Chen
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Androgen receptor (AR) activation and repression dual-functionality only became known recently and still remains intriguing in prostate cancer (PCa). MYC is a prominent oncogene that functionally entangles with AR signaling in PCa
Externí odkaz:
https://doaj.org/article/b8dc90534bbf4665ae410b4fe0f9222d
Akademický článek
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Autor:
Deli Liu, Ashley S. Doane, Olivier Elemento, Andrea Sboner, Lesa D. Deonarine, Andries M. Bergman, Elissa W.P. Wong, Noah Dephoure, Mark A. Rubin, Michael A. Augello, Dennis Huang, Mirjam Blattner, Himisha Beltran, Brian D. Robinson, Suzan Stelloo, Christopher E. Barbieri, Wilbert Zwart, Yu Chen
Publikováno v:
Cancer Cell, 35(4), 603-617.e8. Cell Press
Deletion of the gene encoding the chromatin remodeler CHD1 is among the most common alterations in prostate cancer (PCa); however, the tumor-suppressive functions of CHD1 and reasons for its tissue-specific loss remain undefined. We demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03e71ea8583cd3049584b23988b251a
Publikováno v:
Nash, C, Boufaied, N, Mills, I G, Franco, O E, Hayward, S W & Thomson, A A 2017, ' Genome-wide analysis of AR binding and comparison with transcript expression in primary human fetal prostate fibroblasts and cancer associated fibroblasts ', Molecular and Cellular Endocrinology . https://doi.org/10.1016/j.mce.2017.05.006
The androgen receptor (AR) is a transcription factor, and key regulator of prostate development and cancer, which has discrete functions in stromal versus epithelial cells. AR expressed in mesenchyme is necessary and sufficient for prostate developme