Influence of family history on penetrance of hereditary cancers in a population setting

Autor: L Jackson, MN Weedon, JW Harrison, AR Wood, KS Ruth, J Tyrrell, CF Wright

BackgroundWe sought to investigate how penetrance of familial cancer syndromes varies with family history using a population-based cohort.MethodsWe analysed 454,712 UK Biobank participants with exome sequence and clinical data. We identified particip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5942e3479cbb3e09bb4bb2f1e138256
https://doi.org/10.1101/2022.07.08.22277415

Isolation of Acholeplasma oculi from calves

Autor: AR Wood, GE Jones, AG Rae

Publikováno v: Veterinary Record. 120:144-144

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81113ad8ae5aaa839e987dd903311f37
https://doi.org/10.1136/vr.120.6.144

Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height.

Autor: Hawkes G; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK. g.hawkes2@exeter.ac.uk., Beaumont RN; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Li Z; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Mandla R; Department of Medicine, Harvard Medical School, Broad Institute, Boston, Massachusetts, USA., Li X; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Albert CM; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Arnett DK; Provost Office, University of South Carolina, Columbia, SC, USA., Ashley-Koch AE; Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA., Ashrani AA; Division of Hematology, Department of Medicine, Mayo Clinic Rochester, Rochester, MN, USA., Barnes KC; Department of Medicine, School of Medicine, University of Colorado, Aurora, CO, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Carson AP; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Chami N; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Chung MK; Department of Cardiovascular Medicine, Heart, Vascular & Thoracic Institute, Cleveland, OH, USA., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, The University of Texas Rio Grande Valley, Brownsville, TX, USA., Darbar D; Division of Cardiology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA., Ellinor PT; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Fornage M; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Gordeuk VR; Department of Medicine, School of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA., Hwu CM; Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan., Kalyani RR; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kaplan R; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lubitz SA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Minster RL; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA., Naseri T; Naseri & Associates Public Health Consultancy Firm and Family Health Clinic, Apia, Samoa.; International Health Institute, Brown University, Providence, Rhode Island, US., Viali S; Oceania University of Medicine, Apia, Samoa.; School of Medicine, National University of Samoa, Apia, Samoa.; Dept of Chronic Disease Epidemiology, Yale University, New Haven, Connecticut, US., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Murabito JM; Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Palmer ND; Department of Biochemistry, Wake Forest University School of Medicine, Winston-, Salem, NC, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Departments of Medicine, Epidemiology, and Health Systems and Population Health, University of Washington, Seattle, WA, USA., Redline S; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Shoemaker MB; Department of Medicine, Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Silverman EK; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Telen MJ; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Yanek LR; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zhou H; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Liu CT; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Justice AE; Population Health Sciences, Geisinger, Danville, PA, USA., Locke JM; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Owens N; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Murray A; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Patel K; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Frayling TM; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Wright CF; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Wood AR; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Lin X; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Statistics, Harvard University, Cambridge, MA, USA., Manning A; Department of Medicine, Harvard Medical School, Broad Institute, Boston, Massachusetts, USA., Weedon MN; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK. m.n.weedon@exeter.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2024 Oct 03; Vol. 15 (1), pp. 8549. Date of Electronic Publication: 2024 Oct 03.

COVID-19 Implications on Worksite Wellness Programming.

Autor: Underwood RA; Southeastern Louisiana University, Hammond, LA, USA., Wood AR; Southeastern Louisiana University, Hammond, LA, USA., Wood RJ; Southeastern Louisiana University, Hammond, LA, USA., Broussard RB; Southeastern Louisiana University, Hammond, LA, USA., Broyles ST; Pennington Biomedical Research Center and Louisiana State University Health Sciences Center, Baton Rouge, LA, USA.

Publikováno v: Health promotion practice [Health Promot Pract] 2024 Sep; Vol. 25 (5), pp. 774-778. Date of Electronic Publication: 2024 May 14.

The role of accelerometer-derived sleep traits on glycated haemoglobin and glucose levels: a Mendelian randomization study.

Autor: Liu J; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. ieu_james.liu@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. ieu_james.liu@bristol.ac.uk.; Nuffield Department of Population Health, Oxford Population Health, University of Oxford, Oxford, UK. ieu_james.liu@bristol.ac.uk., Richmond RC; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Anderson EL; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Division of Psychiatry, University College of London, London, UK., Bowden J; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; College of Medicine and Health, The University of Exeter, Exeter, UK., Barry CS; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Dashti HS; Centre for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA., Daghlas IS; Centre for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA., Lane JM; Centre for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA., Kyle SD; Sir Jules Thorn Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Vetter C; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA., Morrison CL; Department of Psychology & Neuroscience and Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA., Jones SE; Institute for Molecular Medicine Finland, University of Helsinki, Uusimaa, Finland., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, Exeter, UK., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, Exeter, UK., Wright AK; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Carr MJ; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.; National Institute for Health Research (NIHR) Greater Manchester Patient Safety Translational Research Centre, University of Manchester, Manchester, UK., Anderson SG; George Alleyne Chronic Disease Research Centre, Caribbean Institute of Health Research, University of the West Indies, Kingston, Jamaica.; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Emsley RA; Department of Biostatistics and Health Informatics, King's College London, London, UK., Ray DW; Oxford Centre for Diabetes, Endocrinology and Metabolism, and Oxford Kavli Centre for Nanoscience Discovery, University of Oxford, Oxford, UK.; NIHR Oxford Health Biomedical Research Centre, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK., Weedon MN; Genetics of Complex Traits, University of Exeter Medical School, Exeter, UK., Saxena R; Centre for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Rutter MK; NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.; Diabetes, Endocrinology and Metabolism Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, NIHR Manchester Biomedical Research Centre, Manchester, UK.; Division of Diabetes, Endocrinology and Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Lawlor DA; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and The University of Bristol, Bristol, UK.

Publikováno v: Scientific reports [Sci Rep] 2024 Jun 28; Vol. 14 (1), pp. 14962. Date of Electronic Publication: 2024 Jun 28.