Zobrazeno 1 - 10
of 24
pro vyhledávání: '"AR Noort"'
Publikováno v:
Annals of the Rheumatic Diseases. 75:137.2-137
Background The nuclear factor (NF)-κB family of transcription factors has a key role in the regulation of inflammation. We have previously demonstrated that activation of noncanonical NF-κB signalling in dendritic cells (DC) via CD40 stimulation is
Publikováno v:
Annals of the Rheumatic Diseases. 75:A18.2-A18
Background The nuclear factor (NF)-κB family of transcription factors has a key role in the regulation of inflammation. We have previously demonstrated that activation of noncanonical NF-κB signalling in dendritic cells (DC) via CD40 stimulation is
Autor:
Sander W. Tas, Leonie F. A. Huitema, Louis Boon, M C Lebre, Franciscus Kroese, AR Noort, Boy Helder
Publikováno v:
Annals of the Rheumatic Diseases. 74:423.3-423
Background The nuclear factor (NF)-κB family of transcription factors has a key role in the regulation of inflammation. Ligation of CD40 on dendritic cells can induce early production of inflammatory mediators via the canonical NF-κB pathway, as we
Publikováno v:
Annals of the Rheumatic Diseases. 74:654.2-654
Background Angiogenesis is a crucial mediator in rheumatoid arthritis (RA) pathogenesis and blocking this process is thought to have therapeutic potential in ameliorating the disease. Current in vitro models of angiogenesis focus solely on endothelia
Publikováno v:
Annals of the Rheumatic Diseases. 74:A63.1-A63
Background Angiogenesis is a crucial mediator in rheumatoid arthritis (RA) pathogenesis. Current in vitro models of angiogenesis focus solely on endothelial cells (EC), however, RA fibroblast like synoviocytes (FLS) also contribute to this process. T
Autor:
P.P. Tak, C van der Leij, Kpm van Zoest, M. Maas, Mjh de Hair, IY Choi, Sander W. Tas, AR Noort, KI Maijer, Danielle M. Gerlag
Publikováno v:
Annals of the Rheumatic Diseases. 74:A64.1-A64
Background and objectives The NF-κB family of transcription factors is strongly involved in synovial inflammation. We have previously shown that NF-κB-inducing kinase (NIK) is a key regulator of inflammation-induced angiogenesis in rheumatoid arthr
Publikováno v:
Annals of the Rheumatic Diseases. 74:A22.2-A22
Publikováno v:
Annals of the Rheumatic Diseases. 73:842.1-842
Background Angiogenesis plays a crucial role in the progression of rheumatoid arthritis (RA) and is considered a switch from acute to chronic inflammation. Previously, we have demonstrated that NF-κB inducing kinase (NIK) mediated activation of the
Autor:
Natalie Papazian, AR Noort, K P M van Zoest, Paul P. Tak, L G M van Baarsen, Tom Cupedo, Sander W. Tas
Publikováno v:
Annals of the Rheumatic Diseases. 73:A34.2-A35
Background and Objectives Tertiary lymphoid structures (TLS) can be observed in rheumatoid arthritis (RA) synovial tissue, and often contain high endothelial venules (HEV) and follicular dendritic cells (FDC). Endothelial cell (EC)-specific lymphotox
Publikováno v:
Annals of the Rheumatic Diseases. 73:A21.2-A21
Background Autoimmune Regulator (AIRE) is a transcription factor that is involved in the negative selection of self-reactive thymocytes in the thymus and therefore is pivotal in the establishment of central tolerance. Recently, AIRE has also been det