Zobrazeno 1 - 10
of 301
pro vyhledávání: '"AQP9"'
Autor:
Katharina Rump, Michael Adamzik
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Aquaporins (AQPs), a family of membrane proteins that facilitate the transport of water and small solutes, have garnered increasing attention for their role in sepsis, not only in fluid balance but also in immune modulation and metabolic regulation.
Externí odkaz:
https://doaj.org/article/bddf24b72b914314875706ea3952a65a
Autor:
Minhao Yu, Yuan Shi, Yuan Gao, Yang Luo, Yihua Jin, Xiaoyi Liang, Zhuoran Tao, Guojun Zhu, Haiping Lin, Hao Li, Jun Qin, Zhijun Cao, Ming Zhong
Publikováno v:
Pharmacological Research, Vol 203, Iss , Pp 107172- (2024)
Although anti-TNF antibodies are extensively used to treat Crohn's disease (CD), a significant proportion of patients, up to 40%, exhibit an inadequate response to this therapy. Our objective was to identify potential targets that could improve the e
Externí odkaz:
https://doaj.org/article/5afee8dc5a4e4a10bb2a3c49cff27946
Autor:
Yu Wu, Qiuhua Li, Junxi Cao, Fenling Fan, Lishe Gan, Rihui Wu, Jingwei Jin, Ruohong Chen, Lingli Sun, Zhenbiao Zhang, Xingfei Lai, Wing-Leung Wong, Shili Sun, Dongli Li
Publikováno v:
Food & Nutrition Research, Vol 67, Pp 1-12 (2023)
Background: Black tea is fully fermented tea with abundant functional components that benefit the gastrointestinal tract. But whether black tea extract relieves constipation is unknown. Therefore, we used loperamide to induce constipation in mice to
Externí odkaz:
https://doaj.org/article/223fdd1e7f054400a88225df7243ecca
Autor:
Lin Zhang, Yue Liu, Kaiyue Wang, Xiangqin Ou, Jiashun Zhou, Houliang Zhang, Min Huang, Zhenfang Du, Sheng Qiang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Acute myocardial infarction (AMI) has two clinical characteristics: high missed diagnosis and dysfunction of leukocytes. Transcriptional RNA on leukocytes is closely related to the course evolution of AMI patients. We hypothesized
Externí odkaz:
https://doaj.org/article/75fa243346e44b6cb2b02767e1dc1f58
Autor:
Wojciech Czyżewski, Jakub Litak, Jan Sobstyl, Tomasz Mandat, Kamil Torres, Grzegorz Staśkiewicz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6553 (2024)
Aquaporins (AQPs), particularly AQP4, play a crucial role in regulating fluid dynamics in the brain, impacting the development and resolution of edema following traumatic brain injury (TBI). This review examines the alterations in AQP expression and
Externí odkaz:
https://doaj.org/article/7609a1fcd70c499c96dae3a42a04a6a8
Autor:
Patrick Thon, Tim Rahmel, Dominik Ziehe, Lars Palmowski, Britta Marko, Hartmuth Nowak, Alexander Wolf, Andrea Witowski, Jennifer Orlowski, Björn Ellger, Frank Wappler, Elke Schwier, Dietrich Henzler, Thomas Köhler, Alexander Zarbock, Stefan Felix Ehrentraut, Christian Putensen, Ulrich Hermann Frey, Moritz Anft, Nina Babel, Barbara Sitek, Michael Adamzik, Lars Bergmann, Matthias Unterberg, Björn Koos, Katharina Rump
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1209 (2024)
Sepsis involves an immunological systemic response to a microbial pathogenic insult, leading to a cascade of interconnected biochemical, cellular, and organ–organ interaction networks. Potential drug targets can depict aquaporins, as they are invol
Externí odkaz:
https://doaj.org/article/951ca4e8f50f4c998996a3ed93dc1ee1
Akademický článek
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Autor:
Wanbin Fu, Gelan Zhu, Lan Xu, Jia Liu, Xiaofeng Han, Junying Wang, Xinpeng Wang, Jian Hou, Huanbin Zhao, Hua Zhong
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Arsenic trioxide (ATO) is highly effective in acute promyelocytic leukemia (APL) patients, but it fails to show satisfactory efficacy in other acute myeloid leukemia (AML) patients with non-APL subtypes. Different from the APL cel
Externí odkaz:
https://doaj.org/article/0ff84b10704849a0a9d84dfb2c1d627f
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Laryngeal cancer represents a common malignancy that originates from the larynx, with unfavorable prognosis. Herein, this study systematically analyzed the immune signatures of laryngeal cancer and to evaluate their roles on tumor
Externí odkaz:
https://doaj.org/article/fcf0898ab74b45c4a3f64c2b2cbe76b8
Publikováno v:
Biochemistry and Biophysics Reports, Vol 31, Iss , Pp 101317- (2022)
Macrophages play a major role in the immune defense against pathogenic factors; however, they can lead to tumor exacerbation and metastasis, as the tumor microenvironment (TME) polarizes tumor-associated macrophages (TAMs) into the M2 subtype. Lactat
Externí odkaz:
https://doaj.org/article/91e68da2779b42c9a59bd916306781af